Product image of Natriumchlorid Fresenius Kabi (Sodium Chloride) supplied by GNH India

Natriumchlorid Fresenius Kabi

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchlorid Fresenius Kabi (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumchlorid Fresenius Kabi, is an intravenous electrolyte solution presented as an injection solution for IV use. It restores extracellular sodium and chloride balance and provides isotonic fluid volume for patients requiring fluid replacement and electrolyte replenishment. It is manufactured in the European Union under strict pharmacopeial standards and is indicated for a broad range of clinical settings, including surgery and critical care.

GNH India supplies Natriumchlorid Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide, ensuring quality and regulatory compliance.

Manufacturer / TM Owner

Fresenius Kabi Nv/Sa

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Natriumchlorid Fresenius Kabi is used in clinical situations that require restoration of extracellular fluid volume and electrolyte balance.
  • Fluid replacement: restores intravascular volume in patients with dehydration or blood loss.
  • Electrolyte replenishment: corrects sodium and chloride deficits in hyponatremia.
  • Surgical irrigation: provides isotonic solution for intra‑operative flushing and wound care.
  • Critical care: maintains hemodynamic stability in intensive care unit patients.

How It Works

  • Sodium chloride injection delivers sodium (Na⁺) and chloride (Cl⁻) ions directly into the bloodstream, increasing extracellular osmolarity. The added ions expand the intravascular compartment, drawing water into the vascular space and raising plasma volume. This osmotic effect normalizes serum sodium and chloride concentrations, supporting cellular function and blood pressure maintenance. The solution is isotonic, matching physiological tonicity, which minimizes cellular swelling or shrinkage.

Side Effects

Intravenous sodium chloride may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Injection site pain: mild discomfort at the infusion site.
  • Phlebitis: inflammation of the vein used for administration.
  • Transient hypernatremia: temporary rise in serum sodium levels.
  • Fluid overload: excess extracellular fluid leading to mild edema.

Serious or Rare Side Effects

  • Severe hypernatremia: marked increase in serum sodium causing neurological symptoms.
  • Anaphylactoid reaction: rare hypersensitivity with rash, bronchospasm, or hypotension.
  • Electrolyte imbalance: severe shifts in potassium or calcium secondary to rapid infusion.
  • Cardiac arrhythmia: abnormal heart rhythm associated with electrolyte disturbances.

Precautions & Warnings

  • When using Natriumchlorid Fresenius Kabi, clinicians should observe specific safety measures to minimize risks.
  • Assess volume status: evaluate patient’s fluid balance before administration.
  • Monitor electrolytes: check serum sodium and chloride levels during therapy.
  • Adjust infusion rate: tailor speed to patient’s cardiac and renal function.
  • Avoid rapid large-volume bolus in heart failure: may precipitate pulmonary edema.
  • Store below 25°C: keep in original container, protect from moisture and light.

Avoid Interactions

Sodium chloride infusion can interact with other agents, influencing electrolyte balance or fluid status.

Major Interactions (Avoid)

  • Hypertonic glucose solutions: concurrent use may cause severe hypernatremia.
  • Potassium chloride IV: combined high electrolyte load can lead to cardiac arrhythmias.
  • Diuretics (loop, thiazide): may exacerbate electrolyte shifts if not monitored.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance risk of hyperkalemia when sodium balance changes.
  • Corticosteroids: can increase sodium retention, requiring careful volume assessment.
  • Blood products (packed RBCs): concurrent infusion may affect overall fluid volume.

Frequently Asked Questions

Natriumchlorid Fresenius Kabi is an intravenous sodium chloride solution used to replace lost body fluids and restore normal electrolyte concentrations. It is commonly employed in dehydration, postoperative care, trauma, and any clinical situation where isotonic fluid volume needs to be rapidly expanded.

The solution supplies sodium and chloride ions directly into the bloodstream, raising extracellular osmolarity. This draws water from the intracellular and interstitial spaces into the vascular compartment, expanding plasma volume and correcting low serum sodium or chloride levels while maintaining physiological tonicity.

The dose is individualized by the prescribing clinician based on the patient’s fluid deficit, electrolyte status, body weight, and clinical condition. Dosing calculations consider the required volume of isotonic fluid and the concentration of sodium chloride needed to achieve therapeutic goals.

Limited specific data are available for this product in pregnancy or lactation. Because isotonic saline is a standard component of fluid therapy, it may be used when clearly needed, but the prescriber should weigh potential benefits against any theoretical risks and monitor maternal and fetal status closely.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Natriumchlorid Fresenius Kabi is a 0.9% sodium chloride injection, equivalent in concentration to other standard isotonic saline solutions. Its EU manufacturing origin ensures compliance with European pharmacopeial standards. Clinically, it offers the same efficacy as other 0.9% saline brands, with selection often based on supplier reliability, packaging, and regulatory preferences.

Store the product below 25 °C in its original packaging, protecting it from moisture and direct light. Do not freeze the solution. Before use, inspect the container for leaks or particulate matter, and allow the solution to reach room temperature if it has been refrigerated during transport.

The solution is given intravenously, either as a direct infusion or diluted in compatible IV fluids. Administration rate should be adjusted to the patient’s cardiovascular and renal status, and infusion sets should be primed to avoid air embolism. Peripheral or central venous access may be used depending on the required volume.

Serious risks include severe hypernatremia, which can cause neurological disturbances, fluid overload leading to pulmonary edema, and rare anaphylactoid reactions. Rapid infusion of large volumes in patients with compromised cardiac or renal function can precipitate these complications, so careful monitoring is essential.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled heart failure, severe renal impairment, or those at high risk of fluid overload should avoid routine use. Additionally, individuals receiving incompatible IV medications that may precipitate with chloride should be evaluated before administration.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.