Product image of Natriumchlorid Kabipac (Sodium Chloride) supplied by GNH India

Natriumchlorid Kabipac

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchlorid Kabipac (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumchlorid Kabipac, is an electrolyte presented as an injection solution for intravenous use. It restores extracellular sodium and chloride concentrations and expands intravascular volume, supporting fluid replacement in patients with hypovolemia or hyponatremia.

GNH India supplies Natriumchlorid Kabipac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, including acute care settings.

Manufacturer / TM Owner

Fresenius Kabi Nv/Sa

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Indications & Clinical Uses

Natriumchlorid Kabipac, an intravenous sodium chloride solution, is used in fluid and electrolyte replacement therapy.

  • Hypovolemia: restores intravascular volume and improves circulatory stability.
  • Hyponatremia: increases serum sodium concentration to correct electrolyte imbalance.
  • Fluid replacement during surgery or trauma: provides isotonic fluid to maintain hemodynamic parameters.
  • Electrolyte replenishment in burn patients: supplies chloride and sodium to support metabolic needs.

How It Works

  • Sodium chloride dissociates into Na+ and Cl- ions after intravenous administration, raising extracellular osmolarity. The increased osmotic pressure draws water into the vascular compartment, expanding plasma volume and correcting sodium deficits, while chloride helps maintain acid‑base balance and electrical neutrality.

Side Effects

Intravenous sodium chloride may be associated with several adverse reactions, ranging from mild to severe.

Common Side Effects

  • Injection site pain or irritation.
  • Mild hypernatremia.
  • Transient hypertension.
  • Fluid overload (edema).

Serious or Rare Side Effects

  • Severe hypernatremia leading to neurologic symptoms.
  • Pulmonary edema.
  • Allergic reaction or anaphylaxis.
  • Metabolic alkalosis.

Precautions & Warnings

Before using Natriumchlorid Kabipac, clinicians should consider several safety measures.

  • Assess volume status: evaluate patient’s fluid balance prior to infusion.
  • Monitor electrolytes: check serum sodium and chloride levels regularly.
  • Avoid rapid infusion in patients at risk of heart failure: follow recommended infusion rates.
  • Use caution in renal impairment: adjust volume as needed.
  • Pregnancy and lactation: limited data, weigh benefits against potential risks.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Natriumchlorid Kabipac can interact with other medications, requiring careful management.

Major Interactions (Avoid)

  • Concurrent use of hypertonic saline solutions: risk of severe hypernatremia.
  • Combination with diuretics that cause sodium loss: may counteract therapeutic effect.
  • Co‑administration with drugs that increase fluid retention (e.g., corticosteroids) without monitoring.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may affect renal handling of sodium.
  • Lithium therapy: sodium shifts can alter lithium levels.
  • Nephrotoxic antibiotics (e.g., aminoglycosides): monitor renal function.

Frequently Asked Questions

Natriumchlorid Kabipac is an intravenous sodium chloride solution used to replace lost fluids and electrolytes. It is indicated for conditions such as hypovolemia, hyponatremia, and for general fluid replacement during surgery, trauma, or severe burns.

After infusion, sodium chloride dissociates into sodium and chloride ions, raising extracellular osmolarity. This draws water into the vascular space, expanding plasma volume, correcting sodium deficits, and helping maintain acid‑base balance and electrical neutrality.

The dose of Natriumchlorid Kabipac is determined by the prescribing clinician based on the patient’s clinical condition, electrolyte status, and volume needs. Specific dosing regimens are individualized and should follow local medical guidelines.

Safety data for Natriumchlorid Kabipac in pregnancy and lactation are limited. Use is generally considered only when the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made by the treating physician.

To order Natriumchlorid Kabipac, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Natriumchlorid Kabipac is an isotonic sodium chloride injection comparable to standard 0.9% saline. Its composition and clinical effects are similar, but product specifications, regulatory status, and supply chain logistics may differ, making it a suitable alternative for institutions seeking EU‑compliant sources.

Store Natriumchlorid Kabipac at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from direct light, moisture, and extreme temperature fluctuations to maintain product integrity.

Natriumchlorid Kabipac is administered intravenously. The solution is typically infused through a peripheral or central line, following the infusion rate recommended by the prescriber and adjusted according to the patient’s fluid status and clinical response.

Serious risks include severe hypernatremia, which can cause neurologic symptoms, pulmonary edema from fluid overload, and rare allergic reactions such as anaphylaxis. Continuous monitoring of electrolytes and fluid balance helps mitigate these risks.

Patients with known hypersensitivity to sodium chloride solutions, those with uncontrolled heart failure or severe renal impairment where fluid overload is a concern, and individuals for whom alternative fluid management strategies are clinically preferred should avoid using Natriumchlorid Kabipac.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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