Product image of Natriumchloride Dirinco (Sodium Chloride) supplied by GNH India

Natriumchloride Dirinco

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchloride Dirinco (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumchloride Dirinco, is an electrolyte presented as an injection solution for intravenous use. It is employed to restore extracellular sodium and chloride levels and to expand intravascular volume in patients with hypovolemia, electrolyte imbalance, or dehydration.

GNH India supplies Natriumchloride Dirinco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches for global distribution. Customers benefit from reliable logistics and comprehensive technical support.

Manufacturer / TM Owner

Dirinco Bv

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Natriumchloride Dirinco is an intravenous electrolyte solution used in fluid and electrolyte replacement therapy.

  • Hypovolemia: restores circulating blood volume and improves tissue perfusion.
  • Electrolyte imbalance: normalizes serum sodium and chloride concentrations.
  • Dehydration: replenishes extracellular fluid losses and supports hemodynamic stability.
  • Surgical patients: supports intravascular volume during operative procedures.
  • Burn patients: replaces sodium and chloride lost through fluid shifts.

How It Works

  • Sodium chloride infusion increases extracellular sodium and chloride concentrations, which raises plasma osmolality and draws water into the intravascular compartment. This osmotic shift expands circulating volume, improves tissue perfusion, and corrects electrolyte deficits. The solution does not bind to specific receptors but acts through physicochemical principles of fluid balance and ion distribution.

Side Effects

Natriumchloride Dirinco may be associated with the following adverse reactions observed in clinical use.

Common Side Effects

  • Hypernatremia: elevated serum sodium levels.
  • Hyperchloremia: increased serum chloride concentrations.
  • Local irritation: pain or erythema at the infusion site.
  • Phlebitis: inflammation of the vein.
  • Fluid overload: signs of edema or pulmonary congestion.
  • Hypertension: transient rise in blood pressure.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate intervention.
  • Cardiac arrhythmia: caused by rapid shifts in electrolyte balance.
  • Pulmonary edema: accumulation of fluid in the lungs.
  • Severe hypervolemia: dangerous excess of intravascular fluid.
  • Metabolic acidosis: rare disturbance of acid‑base balance.

Precautions & Warnings

When using Natriumchloride Dirinco, consider the following precautions to ensure safe administration.

  • Assess fluid status: evaluate volume needs before initiating therapy.
  • Monitor serum electrolytes: check sodium and chloride levels regularly.
  • Adjust infusion rate in cardiac failure: avoid rapid volume expansion.
  • Use caution in renal impairment: reduced excretion may lead to accumulation.
  • Avoid rapid infusion in neonates: slower rates reduce risk of circulatory overload.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Natriumchloride Dirinco can interact with other agents; the interactions are grouped by clinical significance.

Major Interactions (Avoid)

  • Hypertonic saline solutions: combined use can cause severe hypernatremia.
  • Potassium chloride IV solutions: simultaneous infusion may precipitate electrolyte imbalance.
  • Certain diuretics (e.g., loop diuretics): can exacerbate sodium loss.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance risk of hyperkalemia when combined with other electrolytes.
  • Corticosteroids: can affect fluid retention and electrolyte balance.
  • Other intravenous fluids: monitor total volume to prevent overload.

Frequently Asked Questions

Natriumchloride Dirinco is an intravenous sodium chloride solution used to treat hypovolemia, electrolyte imbalance, and dehydration. It restores extracellular sodium and chloride concentrations, expands intravascular volume, and supports hemodynamic stability in patients who have lost fluid or electrolytes.

Sodium chloride infusion raises plasma sodium and chloride levels, increasing osmotic pressure. This draws water from the interstitial and intracellular spaces into the bloodstream, expanding circulating volume and correcting electrolyte deficits. The process relies on basic fluid‑balance physiology rather than receptor binding.

The prescribed dose of Natriumchloride Dirinco is individualized by the treating clinician based on the patient’s fluid status, electrolyte levels, weight, and clinical condition. Healthcare providers calculate the required volume and infusion rate to achieve safe and effective correction.

Safety data for Natriumchloride Dirinco in pregnancy and lactation are limited. The drug is generally considered compatible with physiological needs, but the prescriber must weigh potential benefits against any unknown risks and monitor maternal and fetal status closely.

To order Natriumchloride Dirinco, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Natriumchloride Dirinco is a standard isotonic sodium chloride solution, similar to normal saline (0.9% NaCl). Compared with balanced crystalloids such as Lactated Ringer’s, it contains only sodium and chloride, making it suitable when additional electrolytes are not required but may increase the risk of hyperchloremic acidosis in large volumes.

Store Natriumchloride Dirinco at 2‑8 °C, protected from light. Do not freeze or shake the container. Keep the product in its original packaging until use to maintain sterility and potency.

Natriumchloride Dirinco is administered intravenously as an injection solution. It can be given as a continuous infusion or intermittent bolus, depending on the clinical scenario and the prescriber’s instructions. Proper aseptic technique and infusion set compatibility are essential.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema, and rare anaphylactic reactions. Monitoring serum electrolytes, fluid balance, and patient vital signs during infusion helps detect and manage these complications promptly.

Patients with known hypersensitivity to sodium chloride solutions, severe hypernatremia, uncontrolled fluid overload, or those at high risk for pulmonary edema should not receive Natriumchloride Dirinco unless the benefits outweigh the risks and close monitoring is ensured.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Chloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT