Product image of Natriumchloride Kabipac Fresenius Kabi (Sodium Chloride) supplied by GNH India

Natriumchloride Kabipac Fresenius Kabi

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchloride Kabipac Fresenius Kabi (Sodium Chloride)

Sodium chloride, the active ingredient in Natriumchloride Kabipac, is an electrolyte presented as an injection solution for intravenous use. It is employed to restore extracellular sodium concentration and osmolarity, supporting fluid replacement, electrolyte balance and treatment of hypovolemia in hospital patients.

GNH India supplies Natriumchloride Kabipac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Nv/Sa

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Indications & Clinical Uses

Natriumchloride Kabipac is used in clinical settings to manage conditions involving fluid and electrolyte disturbances.

  • Fluid replacement: restores intravascular volume in patients with dehydration or blood loss.
  • Electrolyte balance: corrects sodium deficits and maintains osmotic equilibrium.
  • Hypovolemia: supports circulatory volume in shock or severe fluid loss.
  • Dehydration: rehydrates patients unable to maintain adequate oral intake.

How It Works

  • Sodium chloride provides chloride and sodium ions that increase extracellular sodium concentration and osmolarity, thereby drawing water into the vascular compartment and expanding plasma volume. This osmotic effect helps normalize fluid balance and supports cellular function across multiple organ systems.

Side Effects

Adverse reactions may occur with intravenous sodium chloride administration.

Common Side Effects

  • Hypernatremia: elevated serum sodium levels.
  • Infusion site irritation or phlebitis.
  • Mild peripheral edema.
  • Nausea or vomiting.
  • Headache.
  • Transient fever.

Serious or Rare Side Effects

  • Severe hypernatremia leading to neurological impairment.
  • Pulmonary edema in patients with compromised cardiac function.
  • Anaphylactic or severe allergic reactions.
  • Cardiac arrhythmias due to electrolyte imbalance.
  • Seizures associated with extreme hyperosmolarity.
  • Metabolic acidosis in rare cases.

Precautions & Warnings

When using Natriumchloride Kabipac, clinicians should observe several safety measures.

  • Assess baseline serum sodium: verify patient electrolyte status before infusion.
  • Monitor fluid balance: track input/output and weight changes during therapy.
  • Adjust infusion rate in cardiac or renal impairment: avoid fluid overload.
  • Use aseptic technique: prevent contamination of the IV line.
  • Avoid concurrent hypertonic solutions: reduce risk of hypernatremia.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Intravenous sodium chloride can interact with other medications and solutions.

Major Interactions (Avoid)

  • Co‑administration with other hypertonic sodium solutions: may cause severe hypernatremia.
  • Concurrent use of high‑dose potassium chloride: can exacerbate electrolyte disturbances.
  • Simultaneous infusion of hyperosmolar dextrose solutions: increases risk of osmotic shifts.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may amplify sodium loss, requiring careful monitoring.
  • Lithium therapy: sodium levels influence lithium clearance, risking toxicity.
  • NSAIDs or ACE inhibitors: can affect renal function and fluid balance.

Frequently Asked Questions

Natriumchloride Kabipac is an intravenous sodium chloride solution used to replace lost fluids, correct sodium deficits, and restore electrolyte balance in patients with dehydration, hypovolemia, or other conditions requiring rapid volume expansion.

Sodium chloride delivers sodium and chloride ions directly into the bloodstream, raising extracellular sodium concentration and osmolarity. This osmotic effect pulls water into the vascular space, expanding plasma volume and helping maintain normal cellular function and fluid balance.

The dose of Natriumchloride Kabipac is individualized. A qualified prescriber determines the volume and concentration based on the patient’s clinical condition, serum sodium level, and overall fluid requirements.

Safety data for intravenous sodium chloride in pregnancy and lactation are limited. Use is generally considered when the potential benefit outweighs any risk, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Natriumchloride Kabipac is a standard isotonic sodium chloride solution comparable to other 0.9% saline preparations. Its composition, sterility, and EU‑market approval make it suitable for routine fluid replacement, while specific brand formulations may differ in packaging, preservative content, or regulatory status.

The product should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the vial. Before use, inspect for particulate matter or discoloration and follow aseptic techniques when preparing the infusion.

Natriumchloride Kabipac is administered intravenously. The solution is typically diluted in compatible IV fluids or given directly via a controlled infusion pump, with the rate adjusted according to the patient’s fluid status and clinical response.

Serious risks include severe hypernatremia, pulmonary edema, cardiac arrhythmias, and rare anaphylactic reactions. These events are more likely in patients with impaired renal or cardiac function, and they require close monitoring of serum electrolytes and fluid balance.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled hypernatremia, severe congestive heart failure, or those receiving incompatible hypertonic solutions should not receive Natriumchloride Kabipac unless a clinician determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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