Product image of Natriumjodid (I-123) Curiumpharma (Sodium Iodide (123 I)) supplied by GNH India

Natriumjodid (I-123) Curiumpharma

Active Ingredient:
Sodium Iodide (123 I)
Origin:
EU

Natriumjodid (I-123) Curiumpharma (Sodium Iodide (123 I))

Sodium Iodide (I-123), the active ingredient in Natriumjodid (I-123) Curiumpharma, is a radiopharmaceutical presented as a solution for intravenous use. It is used for diagnostic imaging of thyroid function in patients requiring nuclear medicine evaluation.

GNH India supplies Natriumjodid (I-123) Curiumpharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Manufacturer / TM Owner

Curium Netherlands B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Natriumjodid (I-123) is employed in nuclear medicine to assess thyroid tissue uptake and function.

  • Thyroid imaging: provides high‑resolution images of thyroid anatomy and activity.
  • Thyroid scintigraphy: evaluates functional status of the gland in hyper‑ or hypothyroidism.
  • Thyroid nodule assessment: helps differentiate benign from malignant nodules based on iodine uptake patterns.
  • Post‑therapy monitoring: tracks thyroid tissue response after radioactive iodine treatment.

How It Works

  • Sodium Iodide (I-123) is a radioactive isotope of iodine that is actively transported into thyroid follicular cells via the sodium‑iodide symporter. Once inside the gland, the isotope emits gamma photons, which are detected by a gamma camera to generate detailed images of thyroid morphology and functional activity, enabling clinicians to evaluate disorders of thyroid hormone production and tissue architecture.

Side Effects

Adverse reactions are generally mild and related to the intravenous administration of a radioactive tracer.

Common Side Effects

  • Nausea: transient feeling of queasiness after injection.
  • Mild headache: short‑lasting discomfort.
  • Warmth or flushing at the injection site.
  • Metallic taste in the mouth.
  • Transient hypotension: temporary drop in blood pressure.

Serious or Rare Side Effects

  • Allergic reaction or anaphylaxis: severe hypersensitivity requiring immediate medical attention.
  • Radiation‑induced thyroiditis: inflammation of the thyroid gland.
  • Severe hypotension or cardiovascular collapse.
  • Radiation exposure to staff: requires strict safety protocols.
  • Bone marrow suppression (very rare): may affect blood cell production.

Precautions & Warnings

Prior to administration, several safety considerations should be observed.

  • Pregnancy: avoid unless the diagnostic benefit outweighs potential fetal radiation risk.
  • Breastfeeding: discontinue nursing for an appropriate period after dosing.
  • Thyroid disease: assess baseline thyroid function to interpret results accurately.
  • Radiation safety: ensure proper shielding and limit exposure to personnel.
  • Renal function: monitor in patients with impaired clearance as iodine is renally excreted.
  • Store at 2-8°C: keep refrigerated in lead‑lined container, protect from light, do not freeze.

Avoid Interactions

Sodium Iodide (I-123) may interact with medications that influence iodine uptake or thyroid physiology.

Major Interactions (Avoid)

  • Antithyroid drugs (e.g., methimazole, propylthiouracil): markedly reduce tracer uptake.
  • Lithium therapy: decreases iodine transport into the thyroid.
  • Amiodarone: high iodine load interferes with imaging accuracy.
  • High‑dose iodinated contrast agents: compete for the sodium‑iodide symporter.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone replacement: may alter baseline uptake values.
  • Diuretics: affect renal clearance of iodine.
  • ACE inhibitors: can influence blood pressure response during injection.
  • Calcium supplements: may modestly reduce tracer accumulation.
  • Beta‑blockers: may mask symptoms of adverse cardiovascular reactions.

Frequently Asked Questions

Natriumjodid (I-123) is a radiopharmaceutical used in nuclear medicine to image the thyroid gland. It helps clinicians evaluate thyroid function, detect nodules, and assess conditions such as hyperthyroidism or hypothyroidism by providing clear gamma‑camera images of iodine uptake.

Sodium Iodide (I-123) is taken up by thyroid follicular cells via the sodium‑iodide symporter. The radioactive iodine emits gamma photons that are captured by a gamma camera, producing detailed images that reflect the gland’s functional activity and structural characteristics.

The administered activity of Natriumjodid (I-123) is determined by the prescribing physician based on the patient’s age, weight, clinical indication, and the imaging protocol. Exact dosing information is provided in the product’s prescribing information and should not be altered without medical guidance.

Use of Natriumjodid (I-123) during pregnancy or breastfeeding is generally avoided unless the diagnostic benefit clearly outweighs potential risks. The radioactive iodine can cross the placenta and enter breast milk, so clinicians must evaluate each case individually and discuss alternatives when possible.

To request Natriumjodid (I-123), submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Natriumjodid (I-123) offers a favorable half‑life and gamma‑energy profile that yields high‑quality images with lower radiation dose compared with I-131. Unlike technetium‑99m agents, I-123 provides superior thyroid specificity, making it the preferred choice for detailed functional assessment of the thyroid.

The product should be stored refrigerated at 2‑8 °C in its original lead‑shielded container. Protect it from light and avoid freezing or shaking. Ensure that the storage area complies with radiation safety regulations and that the product is handled by trained personnel using appropriate shielding.

Natriumjodid (I-123) is administered intravenously by a qualified healthcare professional. The injection is typically performed in a controlled nuclear medicine suite, and patients are monitored for any immediate reactions before proceeding with the imaging procedure.

Serious risks include allergic reactions such as anaphylaxis, radiation‑induced thyroiditis, and rare bone‑marrow suppression. Proper radiation safety measures and patient monitoring are essential to mitigate these risks, and any adverse event should be reported promptly to the treating physician.

Patients with known hypersensitivity to iodine or radiopharmaceuticals, those who are pregnant or breastfeeding without a compelling diagnostic need, and individuals who have recently received large doses of iodinated contrast agents should generally avoid Natriumjodid (I-123) unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Iodide (123 I)

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT