Product image of Natriumklorid B. Braun (Sodium Chloride) supplied by GNH India

Natriumklorid B. Braun

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid B. Braun (Sodium Chloride)

Sodium chloride, the active ingredient in Natriumklorid B. Braun, is an electrolyte solution presented as an injection solution for intravenous use. It helps restore fluid and electrolyte balance in patients experiencing hypovolemia, dehydration, or other conditions that require rapid fluid replacement.

GNH India supplies Natriumklorid B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to global quality standards and provides regulatory documentation, temperature‑controlled logistics, and after‑sales support to ensure product integrity across diverse markets globally.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Natriumklorid B. Braun is used to manage fluid and electrolyte disorders through intravenous fluid replacement.

  • Fluid replacement: restores intravascular volume and supports hemodynamic stability.
  • Electrolyte replenishment: provides sodium and chloride ions to correct hyponatremia and maintain osmotic balance.
  • Hypovolemia: increases circulating blood volume in patients with blood loss or dehydration.

How It Works

  • Sodium chloride injection delivers Na⁺ and Cl⁻ ions directly into the bloodstream, expanding the extracellular fluid compartment. The added osmoles raise plasma osmolarity, drawing water from the intracellular space into the vascular space, which increases circulating volume. This corrects sodium deficits, supports blood pressure, and facilitates the transport of nutrients and waste products. The solution’s isotonic composition mimics physiological plasma, allowing safe and rapid restoration of fluid balance.

Side Effects

Intravenous administration of sodium chloride may be associated with several adverse reactions.

Common Side Effects

  • Pain or irritation at the injection site.
  • Phlebitis or inflammation of the vein.
  • Mild hypernatremia leading to transient thirst.
  • Edema or peripheral swelling.
  • Elevated blood pressure.

Serious or Rare Side Effects

  • Fluid overload causing pulmonary edema.
  • Severe hypernatremia with neurological symptoms.
  • Cardiac arrhythmias due to electrolyte imbalance.
  • Anaphylactoid reactions or severe hypersensitivity.
  • Infection at the catheter insertion site.

Precautions & Warnings

When using Natriumklorid B. Braun, clinicians should observe several precautionary measures to ensure patient safety.

  • Assess fluid status: evaluate volume status and electrolyte levels before infusion.
  • Monitor serum electrolytes: check sodium and chloride concentrations during therapy.
  • Adjust infusion rate: reduce speed in patients with cardiac or renal impairment.
  • Use caution in hypertension: avoid rapid large-volume administration in hypertensive individuals.
  • Avoid rapid bolus in neonates: administer slowly to prevent circulatory stress.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Sodium chloride solution can interact with other medications or fluids, influencing electrolyte balance and infusion compatibility.

Major Interactions (Avoid)

  • Co‑administration with hypertonic saline: may cause severe hypernatremia.
  • Simultaneous infusion with calcium‑containing solutions: risk of precipitation.
  • Use with diuretics that cause potassium loss: can exacerbate electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • Concomitant use with nephrotoxic drugs: monitor renal function and fluid status.
  • Combination with antihypertensive agents: observe blood pressure changes.
  • Concurrent administration with blood products: ensure compatible infusion rates.

Frequently Asked Questions

Natriumklorid B. Braun is an intravenous sodium chloride solution used to replace lost fluids, replenish sodium and chloride electrolytes, and treat conditions such as hypovolemia, dehydration, and electrolyte imbalance. It is commonly administered in hospitals and clinical settings where rapid restoration of extracellular fluid volume is required.

Sodium chloride provides Na⁺ and Cl⁻ ions that expand the extracellular fluid compartment when infused intravenously. The added osmoles increase plasma osmolarity, pulling water from cells into the bloodstream, which raises circulating volume, supports blood pressure, and corrects sodium deficits, thereby restoring normal fluid and electrolyte homeostasis.

The appropriate dose is determined by the prescribing clinician based on the patient’s clinical condition, degree of fluid loss, serum electrolyte levels, and overall fluid status. Dosage calculations consider body weight, target volume replacement, and any concurrent medical conditions, and are individualized for each patient.

Limited specific data are available for this product in pregnancy or lactation. Sodium chloride is a naturally occurring electrolyte, and short‑term use may be considered when clinically indicated, but the prescriber should weigh potential benefits against any unknown risks and monitor maternal and fetal status closely.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Natriumklorid B. Braun is an isotonic sodium chloride solution comparable to other 0.9% NaCl injections on the market. Unlike balanced crystalloids such as Ringer’s lactate, it contains only sodium and chloride, making it suitable when a pure chloride load is desired. Brand‑specific manufacturing standards and regulatory compliance may differ, but the clinical effect is similar.

The product should be stored at ambient temperature, typically below 25 °C, in its original sealed container. Protect it from direct sunlight, excessive moisture, and physical shock. Do not freeze the solution, and inspect the vial for particulate matter or discoloration before use.

Natriumklorid B. Braun is administered intravenously, either as a continuous infusion or as a controlled bolus, depending on the clinical scenario. The infusion rate is set by the healthcare professional, and the solution is delivered through a sterile IV line using standard aseptic techniques.

Serious risks include fluid overload leading to pulmonary edema, severe hypernatremia that can cause neurological disturbances, cardiac arrhythmias from electrolyte imbalance, and rare anaphylactoid reactions. Patients with compromised cardiac or renal function require close monitoring to mitigate these risks.

Contraindications include patients with known hypersensitivity to sodium chloride solutions, severe hypernatremia, existing fluid overload, uncontrolled hypertension, or severe renal failure where additional volume could be harmful. Clinicians should evaluate each patient’s condition before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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