Product image of Natriumklorid B. Braun (Sodium Chloride) supplied by GNH India

Natriumklorid B. Braun

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid B. Braun (Sodium Chloride)

Sodium chloride, the active ingredient in Natriumklorid B. Braun, is an electrolyte presented as an injection solution for intravenous use. It is employed to correct fluid and electrolyte imbalances such as hypovolemia and hyponatremia in hospitalized patients.

GNH India supplies Natriumklorid B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The product is manufactured in the European Union under strict quality standards. Its compliance with EU pharmacopeia ensures consistent sterility and isotonicity for clinical use.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Natriumklorid B. Braun is an intravenous electrolyte solution used in conditions requiring fluid and sodium replacement.

  • Fluid replacement: restores intravascular volume in patients with blood loss or dehydration.
  • Electrolyte replenishment: supplies sodium and chloride to correct electrolyte deficits.
  • Hypovolemia: increases circulating blood volume to improve tissue perfusion.
  • Hyponatremia: raises serum sodium concentration to normal levels.

How It Works

  • Sodium chloride injection delivers Na+ and Cl- ions directly into the bloodstream, expanding the extracellular fluid compartment. The added sodium increases osmotic pressure, drawing water into the vascular space, while chloride helps maintain electrical neutrality. This osmotic shift restores intravascular volume and corrects serum electrolyte concentrations, supporting normal cellular function and hemodynamic stability.

Side Effects

Adverse reactions may occur with any intravenous therapy and should be monitored.

Common Side Effects

  • Injection site pain or irritation.
  • Phlebitis or mild inflammation of the vein.
  • Transient hypernatremia with rapid infusion.
  • Mild headache or nausea.

Serious or Rare Side Effects

  • Severe hypernatremia leading to neurological symptoms.
  • Fluid overload causing pulmonary edema.
  • Anaphylactic or severe allergic reaction.
  • Cardiac arrhythmia due to electrolyte imbalance.
  • Severe hypotension or shock.

Precautions & Warnings

Use of Natriumklorid B. Braun requires careful clinical assessment.

  • Assess fluid status: evaluate patient volume and hydration before administration.
  • Monitor electrolytes: check serum sodium and chloride levels regularly during therapy.
  • Adjust infusion rate: tailor to individual hemodynamic needs and cardiac function.
  • Use caution in renal impairment: risk of fluid overload and electrolyte accumulation.
  • Store at ambient temperature: keep in original packaging, protect from light and moisture.

Avoid Interactions

Sodium chloride can interact with other agents that affect fluid balance or electrolyte homeostasis.

Major Interactions (Avoid)

  • Concomitant hypertonic saline: may cause severe hypernatremia.
  • Loop diuretics: can lead to rapid shifts in sodium and fluid volume.
  • ACE inhibitors or ARBs: increased risk of hypotension when large volumes are infused.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may impair renal sodium handling.
  • Corticosteroids: can enhance sodium retention and fluid accumulation.
  • Antiepileptic drugs (e.g., phenytoin): may alter serum electrolyte levels.

Frequently Asked Questions

Natriumklorid B. Braun is an intravenous sodium chloride solution used to replace lost fluids and correct electrolyte disturbances. It is indicated for fluid replacement in hypovolemia, electrolyte replenishment in hyponatremia, and as a supportive therapy during surgery or trauma when rapid volume expansion is required.

Sodium chloride provides Na+ and Cl- ions that expand the extracellular fluid compartment. The added sodium creates an osmotic gradient that draws water into the vascular space, increasing blood volume. Chloride maintains electrical neutrality, helping to stabilize membrane potentials and supporting normal physiological functions.

The dose of Natriumklorid B. Braun is determined by the prescribing clinician based on the patient’s fluid status, electrolyte levels, and clinical condition. Dosage is individualized and may be adjusted during therapy according to ongoing monitoring of vital signs and laboratory results.

Safety data for Natriumklorid B. Braun in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order Natriumklorid B. Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Natriumklorid B. Braun is a standard isotonic sodium chloride injection comparable to other 0.9% saline products. Its EU‑origin manufacturing and strict GDP compliance may offer assurance of consistent sterility and isotonicity. Clinically, it provides the same electrolyte composition as other normal saline solutions, making it interchangeable when appropriate.

Store Natriumklorid B. Braun at ambient temperature, preferably below 25 °C, in its original container. Protect the product from direct sunlight, moisture, and physical damage. Do not freeze the solution, and inspect the vial for particulate matter before use.

The product is administered intravenously, either as a slow infusion or a rapid bolus, depending on the clinical situation. Administration should be performed by qualified healthcare personnel using aseptic technique, and the infusion rate should be adjusted according to patient response and monitoring parameters.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema, cardiac arrhythmias due to electrolyte imbalance, and rare anaphylactic reactions. Continuous monitoring of vital signs, fluid balance, and serum electrolytes helps mitigate these risks.

Patients with known hypersensitivity to sodium chloride or any component of the formulation should avoid its use. Caution is advised in individuals with severe renal impairment, uncontrolled heart failure, or conditions predisposing them to fluid overload, where alternative fluid management strategies may be preferred.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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