Product image of Natriumklorid Braun (Sodium Chloride) supplied by GNH India

Natriumklorid Braun

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid Braun (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumklorid Braun, is an electrolyte presented as a sterile solution for injection for intramuscular, intravenous or subcutaneous use. It is employed to restore sodium and chloride concentrations and expand extracellular fluid volume in patients requiring fluid replacement, electrolyte replenishment, or treatment of hypovolemia.

GNH India supplies Natriumklorid Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to EU manufacturing standards and provides reliable logistics for global healthcare providers.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Natriumklorid Braun is used in the management of conditions involving fluid loss or electrolyte imbalance.
  • Fluid replacement: restores intravascular volume in patients with dehydration or blood loss.
  • Electrolyte replenishment: corrects sodium and chloride deficits in hypoelectrolytemia.
  • Hypovolemia: expands extracellular fluid to improve circulatory stability.

How It Works

  • Sodium chloride solution provides exogenous sodium (Na⁺) and chloride (Cl⁻) ions that directly increase plasma osmolarity. The elevated osmolarity draws water into the extracellular compartment, expanding intravascular volume. The supplied ions also replenish depleted electrolyte stores, supporting cellular function and maintaining acid‑base balance. The effect is immediate upon administration, making it suitable for rapid fluid resuscitation.

Side Effects

Sodium chloride injection may be associated with a range of adverse reactions, most of which are related to the infusion process or electrolyte shifts.

Common Side Effects

  • Injection site pain: mild discomfort at the puncture site.
  • Transient hypernatremia: temporary rise in serum sodium.
  • Mild edema: slight swelling due to fluid overload.
  • Fever or chills: reaction to the infusion.

Serious or Rare Side Effects

  • Severe hypernatremia: marked increase in serum sodium leading to neurological symptoms.
  • Pulmonary edema: fluid accumulation in lungs causing respiratory distress.
  • Anaphylactoid reaction: rare hypersensitivity with hypotension, rash, or bronchospasm.

Precautions & Warnings

  • When using Natriumklorid Braun, clinicians should observe several safety considerations to minimize risks.
  • Assess volume status: evaluate patient’s fluid balance before administration.
  • Monitor electrolytes: check serum sodium and chloride levels during therapy.
  • Avoid in fluid overload: contraindicated in patients with congestive heart failure or renal failure.
  • Adjust rate in neonates: use slower infusion rates for infants and children.
  • Store at controlled room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Sodium chloride solution can interact with other therapies, influencing fluid and electrolyte balance.

Major Interactions (Avoid)

  • Congestive heart failure: additional volume may precipitate decompensation.
  • Renal failure with oliguria: risk of severe fluid overload.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may increase sodium loss, requiring dose adjustment.
  • Corticosteroids: can cause sodium retention, enhancing volume expansion.
  • ACE inhibitors or ARBs: may alter potassium balance when combined with saline.

Frequently Asked Questions

Natriumklorid Braun is a sterile sodium chloride solution used to replace lost fluids and electrolytes. It is indicated for fluid replacement, electrolyte replenishment, and the treatment of hypovolemia in patients who have experienced dehydration, blood loss, or other conditions that reduce intravascular volume.

Sodium chloride provides sodium and chloride ions that raise plasma osmolarity. This osmotic shift draws water from the intracellular and interstitial spaces into the bloodstream, expanding the extracellular and intravascular compartments. The added ions also correct electrolyte deficits, supporting nerve, muscle, and acid‑base functions.

The dose of Natriumklorid Braun is individualized by the prescribing clinician based on the patient’s age, weight, clinical condition, and the extent of fluid loss. Healthcare professionals calculate the required volume and concentration to achieve the desired fluid and electrolyte balance.

Safety data for sodium chloride injection in pregnancy and lactation are limited. Because it is a physiologic electrolyte solution, it is generally considered compatible when clinically indicated, but the prescriber must weigh potential benefits against any unknown risks and monitor the mother and fetus closely.

To order Natriumklorid Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and any required import documentation.

Natriumklorid Braun is a standard isotonic sodium chloride solution (0.9% NaCl) similar to other commercial normal saline products. Its clinical profile is comparable, offering rapid volume expansion and electrolyte replacement. Differences may lie in manufacturing origin, packaging, and regulatory compliance, with Natriumklorid Braun meeting EU standards and GNH India’s GDP requirements.

Store Natriumklorid Braun at controlled room temperature, typically below 25 °C. Keep the vials in their original packaging, protect them from direct light, and avoid exposure to moisture. Do not freeze the solution, and ensure the container remains sealed until use.

Natriumklorid Braun is administered by a qualified healthcare professional via intramuscular, intravenous, or subcutaneous injection. The route and infusion rate are selected based on the clinical situation, with intravenous delivery being the most common for rapid fluid resuscitation. Sterile technique and appropriate infusion sets must be used.

Serious risks include severe hypernatremia, which can cause neurological symptoms, and fluid overload leading to pulmonary edema or heart failure exacerbation. Rarely, an anaphylactoid reaction may occur, presenting with hypotension, rash, or bronchospasm. Prompt monitoring of vital signs and electrolyte levels helps mitigate these risks.

Patients with known hypersensitivity to sodium chloride solutions should avoid it. It is also contraindicated in individuals with untreated fluid overload, such as uncontrolled congestive heart failure or severe renal impairment, where additional volume could worsen their condition. Clinical judgment is required for all other cases.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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