Product image of Natriumklorid Braun (Sodium Chloride) supplied by GNH India

Natriumklorid Braun

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid Braun (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumklorid Braun, is a saline presented as a solution for injection for intravenous and subcutaneous use. It restores extracellular sodium and chloride concentrations and expands intravascular volume, aiding fluid replacement and electrolyte replenishment in patients with hypovolemia or dehydration.

GNH India supplies Natriumklorid Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Natriumklorid Braun is used in clinical situations that require rapid restoration of fluid and electrolyte balance.

  • Fluid replacement: restores circulating volume in patients with blood loss or fluid deficits.
  • Electrolyte replenishment: corrects low sodium and chloride levels in dehydration.
  • Hypovolemia: expands intravascular volume to improve tissue perfusion.
  • Dehydration: provides isotonic fluid to rehydrate patients safely.

How It Works

  • Sodium chloride solution provides an isotonic electrolyte load that increases extracellular sodium and chloride concentrations. The resulting osmotic gradient draws water into the vascular compartment, expanding plasma volume and correcting electrolyte imbalances. This action supports hemodynamic stability and improves tissue perfusion in patients with fluid loss or electrolyte disturbances.

Side Effects

Adverse reactions may occur with any intravenous solution. Monitoring and appropriate administration reduce risk.

Common Side Effects

  • Local irritation or pain at the injection site.
  • Mild hypernatremia or hyperchloremia.
  • Fluid overload leading to peripheral edema.
  • Transient hypertension.
  • Nausea or mild vomiting.

Serious or Rare Side Effects

  • Anaphylactic reaction.
  • Severe hypernatremia causing neurologic symptoms.
  • Pulmonary edema or acute heart failure.
  • Cardiac arrhythmia due to electrolyte imbalance.
  • Sepsis from contaminated solution.

Precautions & Warnings

Careful assessment and monitoring are essential when using Natriumklorid Braun.

  • Assess volume status: evaluate patient’s fluid balance before administration.
  • Monitor electrolytes: check serum sodium and chloride levels regularly.
  • Avoid rapid infusion: infuse at recommended rate to prevent circulatory overload.
  • Use with caution in renal or cardiac failure: increased risk of fluid overload.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Sodium chloride solution can interact with other therapies that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Hypertonic saline: concurrent use may cause severe hypernatremia.
  • Potassium chloride infusion: risk of hyperkalemia when combined with high‑dose saline.
  • Certain diuretics (e.g., loop diuretics) in high doses: may exacerbate electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor blood pressure and renal function.
  • NSAIDs: may affect renal handling of sodium.
  • Corticosteroids: can increase sodium retention.
  • Insulin therapy: monitor potassium levels when both are used.

Frequently Asked Questions

Natriumklorid Braun is a sterile sodium chloride solution used to replace lost fluids and electrolytes. It is indicated for fluid replacement, electrolyte replenishment, treatment of hypovolemia, and management of dehydration in hospital and clinical settings.

The solution provides isotonic sodium and chloride ions that increase extracellular concentrations. This creates an osmotic gradient that draws water into the vascular space, expanding plasma volume and correcting electrolyte imbalances, thereby supporting circulatory stability.

The dose of Natriumklorid Braun is determined by the prescribing clinician based on the patient’s fluid loss, electrolyte status, and clinical condition. Healthcare professionals calculate the appropriate volume and rate of infusion for each individual case.

Safety data for Natriumklorid Braun in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Natriumklorid Braun, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Natriumklorid Braun is an isotonic sodium chloride solution comparable to other normal saline products (0.9% NaCl). Its clinical performance is similar, but differences may exist in packaging, sterility assurance, and regulatory compliance, which can influence supplier selection.

The product should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Maintain the original packaging until use to preserve sterility and solution integrity.

Natriumklorid Braun is administered intravenously or subcutaneously by a qualified healthcare professional. The solution is infused through a sterile IV set or syringe, following the prescribed volume and infusion rate to avoid rapid fluid shifts.

Serious risks include severe hypernatremia, pulmonary edema, cardiac arrhythmias due to electrolyte imbalance, and rare anaphylactic reactions. Prompt monitoring of vital signs and electrolyte levels helps mitigate these risks.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled heart failure, severe renal impairment, or those at high risk of fluid overload should avoid using Natriumklorid Braun unless closely monitored by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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