Product image of Natriumklorid Braun (Sodium Chloride) supplied by GNH India

Natriumklorid Braun

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid Braun (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumklorid Braun, is a Electrolyte presented as a solution for injection for intramuscular, intravenous and subcutaneous use. It restores extracellular fluid volume and sodium chloride balance in patients who require fluid and electrolyte replenishment.
GNH India supplies Natriumklorid Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
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Indications & Clinical Uses

Natriumklorid Braun is used to address conditions that involve loss of body fluids and electrolytes.

  • Dehydration: restores fluid volume and corrects electrolyte imbalance in dehydrated patients.
  • Hypovolemia: expands intravascular volume to improve circulatory stability.
  • Fluid replacement: provides isotonic saline for peri‑operative and trauma resuscitation.
  • Electrolyte replenishment: supplies sodium and chloride to maintain normal plasma concentrations.

How It Works

  • Sodium chloride solution delivers Na+ and Cl‑ ions directly into the extracellular compartment, increasing osmolarity and expanding plasma volume. The added sodium promotes water retention, while chloride helps maintain acid‑base balance. This rapid increase in intravascular volume improves tissue perfusion and corrects hyponatremia or chloride deficits, supporting normal cellular function.

Side Effects

Adverse reactions may occur with any parenteral solution.

Common Side Effects

  • Injection site pain or erythema
  • Mild hypernatremia
  • Mild hyperchloremia
  • Fluid overload in susceptible patients
  • Transient fever or chills
  • Local irritation or phlebitis

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypernatremia leading to neurological symptoms
  • Pulmonary edema due to rapid volume expansion
  • Cardiac arrhythmias from electrolyte imbalance
  • Severe thrombophlebitis or thrombosis
  • Sepsis from contaminated solution

Precautions & Warnings

Use Natriumklorid Braun with careful clinical monitoring.

  • Assess baseline electrolyte levels: verify sodium and chloride status before administration.
  • Monitor fluid balance: track input and output to avoid overload.
  • Adjust infusion rate in cardiac or renal impairment: use slower administration.
  • Use caution in hypertensive patients: excess sodium may raise blood pressure.
  • Avoid rapid bolus in neonates and infants: risk of hypernatremia.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Sodium chloride solution can interact with other agents that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Co‑administration with hypertonic saline: risk of severe hypernatremia.
  • Certain IV drug admixtures (e.g., calcium gluconate) that are incompatible.
  • Concurrent use of large‑volume dextrose solutions without electrolyte monitoring.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may cause rapid shifts in sodium and fluid status.
  • Corticosteroids: can enhance fluid retention.
  • ACE inhibitors or ARBs: monitor renal function and potassium levels.
  • NSAIDs: may impair renal handling of sodium.
  • Blood transfusions: watch for cumulative sodium load.

Frequently Asked Questions

Natriumklorid Braun is an injectable sodium chloride solution used to replace lost body fluids and electrolytes. It is indicated for fluid replacement, electrolyte replenishment, treatment of dehydration, and correction of hypovolemia in clinical settings such as surgery, trauma, or severe illness.

The solution provides sodium (Na+) and chloride (Cl‑) ions directly into the bloodstream, increasing extracellular osmolarity and expanding plasma volume. This helps restore normal sodium and chloride concentrations, improves tissue perfusion, and supports acid‑base balance, which are essential for normal cellular activity.

The prescribed dose of Natriumklorid Braun is determined by the treating clinician based on the patient’s fluid status, electrolyte levels, and clinical condition. Healthcare professionals calculate the appropriate volume and rate of infusion to achieve safe and effective fluid replacement.

Safety data for Natriumklorid Braun in pregnancy and lactation are limited. Because sodium chloride is a naturally occurring electrolyte, it may be used when clinically necessary, but the prescriber should weigh potential benefits against any theoretical risks and monitor the mother and infant closely.

To order Natriumklorid Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and required import documentation.

Natriumklorid Braun is an isotonic sodium chloride solution comparable to other 0.9% saline products. Its clinical profile is similar, offering rapid volume expansion and electrolyte replacement. Differences may lie in manufacturing standards, packaging, and regulatory compliance, with Natriumklorid Braun meeting EU quality requirements and being supplied by a GDP‑compliant source.

Store Natriumklorid Braun at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture, direct sunlight, and extreme temperature fluctuations. Do not freeze the solution, and inspect for particulate matter before use.

The product is administered by intramuscular, intravenous, or subcutaneous injection, as directed by a healthcare professional. The infusion rate and volume are adjusted according to the patient’s clinical needs, with careful monitoring of vital signs and electrolyte levels during administration.

Serious risks include severe hypernatremia, pulmonary edema from rapid volume overload, cardiac arrhythmias due to electrolyte disturbances, and rare anaphylactic reactions. Prompt recognition of symptoms such as sudden shortness of breath, chest pain, neurological changes, or allergic signs is essential for immediate medical intervention.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled heart failure, severe renal impairment, or those at risk of fluid overload should avoid Natriumklorid Braun unless a prescriber determines that benefits outweigh risks and close monitoring is ensured.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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