Product image of Natriumklorid Fresenius Kabi (Sodium Chloride) supplied by GNH India

Natriumklorid Fresenius Kabi

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid Fresenius Kabi (Sodium Chloride)

Sodium chloride, the active ingredient in Natriumklorid Fresenius Kabi, is an electrolyte presented as an injection solution for intravenous use. It restores sodium and chloride balance and expands extracellular fluid volume, supporting fluid replacement and electrolyte replenishment in patients with hypovolemia or related conditions.

GNH India supplies Natriumklorid Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Ab

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Indications & Clinical Uses

Natriumklorid Fresenius Kabi is used in clinical settings to manage disorders of fluid and electrolyte balance.

  • Fluid replacement: restores intravascular volume in patients with dehydration or blood loss.
  • Electrolyte replenishment: corrects sodium and chloride deficits during surgery or illness.
  • Hypovolemia: supports circulatory volume to maintain blood pressure and organ perfusion.

How It Works

  • Sodium chloride injection provides exogenous sodium and chloride ions that are readily absorbed into the extracellular compartment. By increasing plasma osmolarity, it draws water into the vascular space, expanding intravascular volume. The added ions also replenish depleted electrolyte stores, helping to normalize cellular function and maintain acid‑base balance.

Side Effects

Adverse reactions may occur with any intravenous electrolyte solution. Monitoring and appropriate infusion rates reduce risk.

Common Side Effects

  • Hypernatremia: elevated serum sodium levels.
  • Hyperchloremia: increased chloride concentration.
  • Phlebitis: inflammation at the infusion site.
  • Infusion site pain or irritation.
  • Edema: peripheral fluid accumulation.
  • Transient hypertension.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response.
  • Cardiac arrhythmia: due to electrolyte imbalance.
  • Pulmonary edema: fluid overload in the lungs.
  • Severe hypernatremia leading to neurological symptoms.
  • Severe hypotension from rapid shifts in fluid balance.

Precautions & Warnings

Careful assessment and monitoring are essential when administering intravenous sodium chloride.

  • Baseline electrolytes: check serum sodium and chloride before infusion.
  • Cardiac/renal disease: adjust infusion rate and volume.
  • Fluid balance: monitor input and output closely.
  • Aseptic technique: use sterile equipment to prevent infection.
  • Neonates and infants: avoid rapid infusion to reduce risk of hypernatremia.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Sodium chloride may interact with other agents that affect fluid and electrolyte status.

Major Interactions (Avoid)

  • Hypertonic saline solutions: concurrent use can cause severe hypernatremia.
  • Potassium chloride infusions: risk of combined electrolyte overload.
  • Certain diuretics (e.g., loop diuretics) at high doses: may exacerbate electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: monitor blood pressure and renal function.
  • NSAIDs: may affect renal handling of sodium.
  • Corticosteroids: can influence fluid retention and electrolyte balance.

Frequently Asked Questions

Natriumklorid Fresenius Kabi is an intravenous sodium chloride solution used to replace lost fluids, replenish sodium and chloride electrolytes, and treat hypovolemia. It is commonly administered in hospitals during surgery, trauma care, or when patients cannot maintain adequate fluid balance orally.

Sodium chloride provides sodium and chloride ions that increase plasma osmolarity, drawing water into the vascular compartment. This expands intravascular volume and restores electrolyte concentrations, supporting blood pressure, tissue perfusion, and normal cellular functions.

The dose of Natriumklorid Fresenius Kabi is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and laboratory values. The healthcare professional calculates the appropriate volume and concentration required for safe and effective therapy.

Sodium chloride is a naturally occurring electrolyte, and limited data suggest it can be used when clinically indicated during pregnancy or lactation. However, the prescriber should evaluate the risk‑benefit profile for each individual, considering maternal and fetal health.

To order Natriumklorid Fresenius Kabi, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Natriumklorid is a simple isotonic sodium chloride solution, whereas other electrolyte products may contain additional ions such as potassium, calcium, or glucose. The choice depends on the specific electrolyte deficits and clinical goals; Natriumklorid is preferred when only sodium and chloride replacement is required.

The product should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use and inspect for particulate matter or discoloration before administration.

Natriumklorid is administered intravenously, typically via a peripheral or central line. The infusion rate is set by the clinician, often using a calibrated infusion pump, and the solution is diluted or given undiluted according to the prescribed protocol.

Serious risks include severe hypernatremia, hyperchloremia, cardiac arrhythmias, pulmonary edema, and anaphylactic reactions. Prompt monitoring of serum electrolytes, fluid balance, and patient vital signs helps mitigate these risks.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled severe hypernatremia, or conditions where rapid fluid expansion is contraindicated (e.g., severe heart failure) should not receive Natriumklorid unless a clinician determines it is essential and safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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