Product image of Natriumklorid Fresenius Kabi (Sodium Chloride) supplied by GNH India

Natriumklorid Fresenius Kabi

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid Fresenius Kabi (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumklorid Fresenius Kabi, is an electrolyte presented as an isotonic saline injection solution for intravenous use. It is employed to restore extracellular fluid volume and sodium balance in patients with dehydration, hypovolemia, or electrolyte loss. It is commonly used in surgical patients and those in intensive care.

GNH India supplies Natriumklorid Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to stringent quality standards and provides reliable logistics for clinical settings.

Manufacturer / TM Owner

Fresenius Kabi Ab

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Indications & Clinical Uses

Sodium Chloride injection is used to address fluid and electrolyte disturbances.

  • Dehydration: restores intravascular volume and corrects sodium deficit.
  • Hypovolemia: expands circulating blood volume to maintain perfusion.
  • Electrolyte imbalance: provides isotonic chloride to normalize serum electrolyte concentrations.
  • Perioperative fluid management: supplies necessary fluid replacement during surgery to support hemodynamic stability.

How It Works

  • The isotonic saline solution delivers sodium (Na⁺) and chloride (Cl⁻) ions directly into the bloodstream, increasing extracellular fluid osmolarity. This draws water into the vascular compartment, expanding plasma volume and correcting sodium‑chloride deficits. The resulting osmotic shift re‑establishes normal fluid balance without altering intracellular concentrations.

Side Effects

Adverse reactions may occur with any intravenous solution.

Common Side Effects

  • Hypernatremia: elevated serum sodium levels.
  • Fluid overload: signs of edema or pulmonary congestion.
  • Injection site discomfort: pain, erythema, or phlebitis.

Serious or Rare Side Effects

  • Anaphylactoid reaction: severe hypersensitivity requiring immediate intervention.
  • Pulmonary edema: life‑threatening accumulation of fluid in the lungs.
  • Cardiac arrhythmia: abnormal heart rhythm due to electrolyte shifts.
  • Sepsis from contaminated solution: systemic infection requiring urgent treatment.

Precautions & Warnings

When using Natriumklorid Injection, clinicians should observe several safety measures.

  • Assess fluid status: evaluate the patient’s volume status before administration.
  • Monitor electrolytes: check serum sodium and chloride levels during therapy.
  • Use aseptic technique: ensure sterile handling to prevent contamination.
  • Adjust infusion rate: tailor the rate to the clinical condition to avoid overload.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Sodium Chloride injection can interact with other intravenous therapies.

Major Interactions (Avoid)

  • Concurrent hypertonic saline solutions: risk of severe hypernatremia.
  • Calcium‑containing IV solutions: may precipitate when mixed.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: potential alteration of renal sodium handling.
  • NSAIDs: may affect renal clearance of sodium.
  • Corticosteroids: can enhance sodium retention, requiring electrolyte monitoring.

Frequently Asked Questions

Natriumklorid Fresenius Kabi is an intravenous sodium chloride solution used to replace lost fluids and electrolytes. It is indicated for conditions such as dehydration, hypovolemia, and electrolyte imbalance, helping to restore normal plasma volume and sodium‑chloride balance in hospitalized patients.

The product provides isotonic sodium (Na⁺) and chloride (Cl⁻) ions directly into the bloodstream. These ions increase extracellular osmolarity, drawing water into the vascular space, expanding plasma volume, and correcting sodium‑chloride deficits without shifting intracellular fluid.

The prescribed dose is determined by the treating physician based on the patient’s clinical condition, fluid losses, and electrolyte status. Dosing is individualized and may be adjusted according to ongoing monitoring of vital signs and laboratory values.

Safety data for this specific formulation in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Natriumklorid is an isotonic saline solution that provides only sodium and chloride, making it a simple electrolyte replacement. Compared with balanced solutions that contain additional ions (e.g., potassium, calcium, lactate), it is useful when only NaCl correction is needed, but it may lack the buffering capacity of balanced crystalloids.

The product must be stored at 2‑8 °C, protected from light, and should not be frozen or shaken. Keep the vial in its original packaging until use and discard any solution that appears cloudy, discolored, or contains particles.

Natriumklorid is administered intravenously, typically via a peripheral or central vein. The infusion rate is set by the prescriber and may be adjusted according to the patient’s hemodynamic response and laboratory results. Administration should follow aseptic technique and standard IV infusion protocols.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema, and rare anaphylactoid reactions. Continuous monitoring of fluid balance, vital signs, and serum electrolytes is essential to detect and manage these complications promptly.

Patients with known hypersensitivity to sodium chloride solutions, those with uncontrolled hypernatremia, or individuals for whom fluid overload would be dangerous (e.g., severe heart failure) should not receive this product unless a careful risk‑benefit assessment is performed by a qualified clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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