Product image of Natriumklorid Fresenius Kabi (Sodium Chloride) supplied by GNH India

Natriumklorid Fresenius Kabi

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumklorid Fresenius Kabi (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumklorid Fresenius Kabi, is an electrolyte presented as an injection solution for intravenous use. It restores extracellular fluid volume and sodium chloride balance, and is employed in fluid replacement, electrolyte balance, and blood pressure support for patients requiring intravenous therapy.

GNH India supplies Natriumklorid Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide. The company adheres to stringent quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Fresenius Kabi Ab

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Indications & Clinical Uses

Natriumklorid is used in clinical situations that require intravenous electrolyte and volume management.

  • Fluid replacement: restores intravascular volume in dehydration or blood loss.
  • Electrolyte balance: corrects sodium chloride deficits in hypovolemia.
  • Blood pressure support: assists in maintaining hemodynamic stability during acute care.

How It Works

  • Sodium chloride in the injectable solution increases extracellular sodium concentration and osmolarity, drawing water from the intracellular and interstitial spaces into the vascular compartment. This expansion of intravascular volume restores fluid balance and corrects hyponatremia, supporting normal cellular function and circulatory stability.

Side Effects

Adverse reactions may occur with intravenous sodium chloride administration.

Common Side Effects

  • Injection site pain: discomfort at the infusion site.
  • Phlebitis: inflammation of the vein used for infusion.
  • Mild hypernatremia: transient elevation of serum sodium.
  • Rash or mild hypersensitivity: skin redness or itching.

Serious or Rare Side Effects

  • Severe hypernatremia: marked increase in serum sodium leading to neurological symptoms.
  • Fluid overload: pulmonary edema or heart failure exacerbation.
  • Anaphylactic reaction: rapid onset of airway compromise and hypotension.
  • Cardiac arrhythmia: caused by abrupt electrolyte shifts.

Precautions & Warnings

When using Natriumklorid, clinicians should consider specific safety measures.

  • Renal impairment: monitor fluid status and serum electrolytes closely.
  • Cardiac failure: avoid excessive volume administration.
  • Electrolyte disorders: verify baseline sodium levels before infusion.
  • Pediatric patients: adjust volume carefully according to weight.
  • Pregnancy: use only if clearly needed after risk assessment.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Intravenous sodium chloride may interact with other medications affecting fluid and electrolyte balance.

Major Interactions (Avoid)

  • Loop diuretics: can cause excessive sodium loss leading to imbalance.
  • Corticosteroids: may increase sodium retention and fluid overload risk.
  • ACE inhibitors combined with potassium supplements: heightened risk of electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • Hypertonic solutions: risk of severe hypernatremia if co‑administered.
  • Blood products: may alter overall electrolyte composition.
  • Other IV electrolytes: adjust dosing to prevent cumulative sodium excess.

Frequently Asked Questions

Natriumklorid Fresenius Kabi is an intravenous sodium chloride solution used to replace lost body fluids, correct sodium chloride deficits, and support blood pressure stability in patients who require rapid volume and electrolyte restoration.

When administered intravenously, sodium chloride raises extracellular sodium concentration and osmotic pressure, pulling water into the vascular space. This expands intravascular volume, restores electrolyte balance, and helps maintain normal cellular and circulatory function.

The dose of Natriumklorid is individualized. A qualified prescriber determines the volume and concentration based on the patient’s clinical condition, fluid losses, and laboratory values. No fixed regimen is provided in the product information.

Safety data for Natriumklorid in pregnancy and lactation are limited. It should be used only when clearly needed and after a careful risk‑benefit assessment by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Natriumklorid is an isotonic sodium chloride solution similar to other normal saline preparations. Compared with hypertonic or balanced electrolyte solutions, it provides a straightforward sodium and chloride load without additional ions, making it suitable for simple volume replacement and sodium correction.

The product must be stored at 2‑8 °C, kept refrigerated, protected from light, and should not be frozen or shaken. Maintain the original packaging until use to preserve sterility and solution integrity.

Natriumklorid is given by intravenous infusion. It may be administered undiluted or diluted in compatible IV fluids according to institutional protocols, with infusion rates adjusted to the patient’s fluid status and clinical response.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema or heart failure, and rare anaphylactic reactions. Monitoring serum sodium, fluid balance, and patient vital signs during infusion helps mitigate these risks.

Patients with existing hypernatremia, uncontrolled fluid overload, severe heart failure, or known hypersensitivity to sodium chloride solutions should not receive Natriumklorid unless a clinician determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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