Natriumoxybat Accord (Sodium Oxybate)

Sodium oxybate binds to GHB and GABA_B receptors in the brain, promoting deep slow‑wave sleep and modulating neurotransmitter activity. This dual action lessens cataplexy attacks and enhances daytime alertness in people with narcolepsy.

The exact dose of sodium oxybate is individualized and set by the prescribing clinician based on the patient’s age, weight, severity of symptoms, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data are limited; sodium oxybate should be used during pregnancy or lactation only if the potential benefit outweighs the possible risk to the fetus or infant. Healthcare providers should discuss these considerations with the patient and a obstetric specialist.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The primary alternative, modafinil, is a wake‑promoting agent that does not address cataplexy. Sodium oxybate, by contrast, improves both nighttime sleep architecture and cataplexy control, offering a broader therapeutic effect for patients whose primary issue includes cataplexy.

Store Natriumoxybat Accord at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed when not in use.

The medication is taken orally, usually in divided doses at night as directed by the prescriber. It is important to follow the exact timing and dosing schedule to achieve optimal therapeutic benefit and to minimize adverse effects.

Serious risks include respiratory depression, severe hypotension, and seizures. Patients should be monitored for signs of breathing difficulty, sudden drops in blood pressure, or convulsive activity, and should seek immediate medical attention if any of these occur.

Individuals with known hypersensitivity to sodium oxybate or other GHB compounds, those with severe respiratory disorders, and patients who consume alcohol heavily should avoid this medication. It is also contraindicated in patients for whom the risks outweigh the therapeutic benefits.