Natterman Melrosum Extra Sterk (Codeine Phosphate Hemihydrate)

After oral administration, codeine is partially metabolised to morphine, which binds to μ‑opioid receptors in the brain and spinal cord. This binding reduces neuronal excitability, decreasing the perception of pain and dampening the cough reflex in the medullary cough centre.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly.

Safety data for codeine use during pregnancy and lactation are limited. Generally, it is avoided unless the benefit outweighs the risk, as it may affect the fetus or infant. Consultation with a healthcare provider is essential before use.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Codeine is a weaker opioid compared with alternatives such as morphine or oxycodone, offering effective pain relief and cough suppression with a lower risk of severe respiratory depression when used at recommended doses. However, it still carries typical opioid risks and may be less potent for severe pain.

Store the tablets at ambient temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect from moisture, heat and direct sunlight to maintain product stability.

The medication is taken orally, usually with a full glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal upset. Follow the prescribing clinician’s instructions for frequency and timing.

The most serious risks include respiratory depression, especially in patients with compromised breathing, severe allergic reactions, and the potential for dependence, tolerance and addiction with prolonged use. Immediate medical attention is required if breathing becomes shallow or stops.

Patients with severe respiratory depression, acute asthma attacks, known hypersensitivity to codeine or other opioids, and children under 12 years (unless specifically prescribed) should avoid this medication. It is also contraindicated in individuals taking MAO inhibitors within 14 days.