Product image of Nausicalm Enfants (Dimenhydrinate) supplied by GNH India

Nausicalm Enfants

Active Ingredient:
Dimenhydrinate
Origin:
EU

Nausicalm Enfants (Dimenhydrinate)

Dimenhydrinate, the active ingredient in Nausicalm Enfants, is a first‑generation antihistamine presented as an oral formulation for pediatric use. It is employed to prevent and treat motion‑induced nausea and vomiting, as well as nausea associated with vertigo, in children.

GNH India supplies Nausicalm Enfants as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Les Laboratoires Brothier Sas

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Indications & Clinical Uses

Dimenhydrinate acts on vestibular and central pathways that trigger nausea and vomiting in children.

  • Motion sickness: prevents and treats motion‑induced nausea and vomiting in pediatric patients.
  • Vertigo‑related nausea: reduces nausea and vomiting associated with vestibular disturbances.
  • General pediatric nausea: alleviates acute nausea and vomiting of various causes in children.

How It Works

  • Dimenhydrinate antagonizes peripheral H1 histamine receptors and exhibits anticholinergic activity, which dampens vestibular stimulation and interrupts the central vomiting reflex. By blocking histamine‑mediated signaling and reducing cholinergic transmission, it decreases the sensation of nausea and the motor response of vomiting.

Side Effects

Dimenhydrinate may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Drowsiness
  • Dry mouth
  • Blurred vision
  • Constipation

Serious or Rare Side Effects

  • Allergic reactions such as rash, swelling, or anaphylaxis
  • Cardiac arrhythmias
  • Severe sedation leading to accidents or respiratory depression

Precautions & Warnings

When using Dimenhydrinate in children, several safety considerations are recommended.

  • Assess age and weight: verify appropriate pediatric dosing before administration.
  • Hypersensitivity: avoid in children with known allergy to dimenhydrinate or other first‑generation antihistamines.
  • Respiratory conditions: use caution in children with asthma or chronic bronchial disease.
  • Sedation monitoring: observe for excessive drowsiness, especially if combined with other CNS depressants.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Dimenhydrinate can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Concurrent first‑generation antihistamines: increased anticholinergic load.
  • Sedatives or alcohol: profound central nervous system depression.
  • Monoamine oxidase inhibitors: risk of hypertensive crisis.

Moderate Interactions (Monitor Closely)

  • Other anticholinergic agents (e.g., atropine): additive anticholinergic effects.
  • Antipsychotics such as phenothiazines: enhanced sedation.
  • Tricyclic antidepressants: increased anticholinergic side effects.

Frequently Asked Questions

Nausicalm Enfants contains dimenhydrinate and is used to prevent and treat motion‑induced nausea and vomiting, as well as nausea associated with vertigo and other acute gastrointestinal disturbances in children.

Dimenhydrinate blocks peripheral H1 histamine receptors and has anticholinergic activity, which reduces vestibular stimulation and interrupts the central pathways that trigger the nausea and vomiting reflex.

The specific dose for each child is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. No universal dosing regimen is provided here.

Safety data for dimenhydrinate in pregnancy and lactation are limited. Use only if clearly needed and after consultation with a qualified healthcare provider, who can weigh potential benefits against possible risks.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Dimenhydrinate is a first‑generation antihistamine, offering both antihistaminic and anticholinergic effects. Compared with newer agents such as ondansetron, it may cause more sedation but is widely available OTC and effective for motion‑related nausea in children.

Store at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

The medication is taken orally, usually as a liquid or chewable tablet formulated for children. It should be given with or without food as directed by the prescriber, and the full dose should be swallowed or consumed according to instructions.

Serious risks include severe allergic reactions (rash, swelling, anaphylaxis), cardiac arrhythmias, and profound sedation that can impair breathing or lead to accidents. Immediate medical attention is required if any of these occur.

Children with known hypersensitivity to dimenhydrinate or other first‑generation antihistamines should avoid the product. It is also contraindicated in patients with certain severe cardiac or respiratory conditions unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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