Product image of Navela (Levonorgestrel) supplied by GNH India

Navela

Active Ingredient:
Levonorgestrel
Origin:
EU

Navela (Levonorgestrel)

Levonorgestrel, the active ingredient in Navela, is a progestin presented as a tablet for oral use. It is used as an emergency contraceptive to prevent pregnancy after unprotected intercourse. Navela provides a rapid, non‑prescription option for post‑coital birth control.

GNH India supplies Navela as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Exeltis Czech S.R.O.

1
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Indications & Clinical Uses

Levonorgestrel is a progestin that acts within the hormonal pathway of contraception.

  • Emergency contraception: prevents pregnancy when taken shortly after unprotected sex.
  • Post‑coital contraception: offers a non‑prescription option to reduce the risk of unintended pregnancy.
  • Prevention of unintended pregnancy after contraceptive failure: provides an additional safeguard when regular methods fail.

How It Works

  • Levonorgestrel binds to progesterone receptors in the hypothalamus and ovary, inhibiting the luteinizing hormone surge and thereby preventing ovulation. It also induces changes in the endometrial lining that reduce the likelihood of implantation should fertilization occur.

Side Effects

Navela may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Abdominal pain: cramping or discomfort.
  • Fatigue: feeling unusually tired.
  • Headache: mild to moderate intensity.
  • Dizziness: brief episodes of light‑headedness.
  • Menstrual changes: spotting or altered timing.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Chest pain: unexpected discomfort in the chest area.
  • Severe abdominal pain: intense, persistent cramps.
  • Vomiting blood: sign of gastrointestinal bleeding.
  • Fainting: sudden loss of consciousness.

Precautions & Warnings

Before using Navela, consider the following safety measures.

  • Timing of administration: take as soon as possible after unprotected intercourse, preferably within 72 hours.
  • Contraindications: avoid if there is a known hypersensitivity to levonorgestrel.
  • Medical conditions: use with caution in women with active liver disease or hormone‑sensitive cancers.
  • Drug interactions: be aware of enzyme‑inducing medications that may lower effectiveness.
  • Pregnancy testing: not indicated for established pregnancy.
  • Store at ambient temperature: keep below 25°C, retain in the original pack, and protect from moisture.

Avoid Interactions

Levonorgestrel can interact with other medicines, affecting its efficacy.

Major Interactions (Avoid)

  • Enzyme inducers (e.g., rifampicin, carbamazepine): may markedly reduce effectiveness.
  • Antifungal agents (e.g., griseofulvin): may lower drug levels.
  • Antiretroviral drugs (e.g., efavirenz): may decrease efficacy.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., phenytoin): may modestly reduce effect.
  • Herbal supplements (e.g., St. John’s wort): may affect hormone levels.
  • Certain antibiotics (e.g., ampicillin): limited evidence, monitor for reduced efficacy.

Frequently Asked Questions

Navela is used as an emergency contraceptive to prevent pregnancy after unprotected sexual intercourse or contraceptive failure. It provides a rapid, non‑prescription option to reduce the risk of unintended pregnancy when taken within the recommended time frame.

Levonorgestrel works by binding to progesterone receptors, which suppresses the luteinizing hormone surge and blocks ovulation. It also alters the endometrial lining, making it less suitable for implantation should fertilization have occurred.

The specific dose of Navela is determined by the prescribing healthcare professional. Typically, an emergency contraceptive regimen involves a single oral dose taken as soon as possible after the event, but the exact amount should follow the prescriber’s instructions.

Navela is intended for use before pregnancy is established and is not a treatment for an existing pregnancy. Limited data are available for use during breastfeeding; however, occasional exposure is not expected to pose significant risk. Women should consult their healthcare provider for personalized advice.

To order Navela, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Navela contains levonorgestrel, the same active ingredient found in many other emergency contraceptive tablets. Compared with copper‑IUD insertion, it is less invasive but may have a slightly shorter window of effectiveness. Relative to newer hormonal options, levonorgestrel remains widely available, OTC in many regions, and has a well‑characterized safety profile.

Navela tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or direct sunlight.

Navela is taken orally as a tablet. The tablet should be swallowed whole with water, preferably as soon as possible after unprotected intercourse. No special preparation is required, but it is recommended to follow any additional instructions provided by the prescribing clinician.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, chest pain, and significant abdominal pain. If any of these symptoms occur, medical attention should be sought immediately. Persistent vomiting or signs of bleeding also warrant prompt evaluation.

Navela should not be used by individuals with a known hypersensitivity to levonorgestrel or any tablet excipients. Women with active liver disease, hormone‑sensitive cancers, or those who are already pregnant should avoid using it unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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