Product image of Naxyl (Dequalinium Chloride) supplied by GNH India

Naxyl

Active Ingredient:
Dequalinium Chloride
Origin:
EU

Naxyl (Dequalinium Chloride)

Dequalinium chloride, the active ingredient in Naxyl, is a quaternary ammonium antiseptic presented as a vaginal antiseptic preparation for intravaginal use. It is employed to manage vaginal infections, including bacterial vaginosis, by targeting a broad spectrum of microorganisms.

GNH India supplies Naxyl as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vivax Pharmaceuticals S.R.O.

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Indications & Clinical Uses

Naxyl is a vaginal antiseptic used to treat conditions affecting the vaginal microbiome.

  • Vaginal infections: reduces microbial load and alleviates symptoms such as discharge and irritation.
  • Bacterial vaginosis: helps restore normal vaginal flora by eliminating pathogenic bacteria.
  • Recurrent vaginal dysbiosis: supports maintenance of a balanced vaginal environment when used as directed.

How It Works

  • Dequalinium chloride disrupts microbial cell membranes by integrating into lipid bilayers, causing loss of cellular integrity. This leads to rapid death of a broad range of bacteria, fungi and protozoa, thereby reducing infection and restoring normal vaginal flora without systemic absorption.

Side Effects

Adverse reactions may occur with intravaginal use of Naxyl.

Common Side Effects

  • Vaginal irritation or burning sensation.
  • Itching or mild discomfort.
  • Increased vaginal discharge.
  • Unpleasant odor.
  • Local allergic reaction (redness, swelling).

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Ulceration of vaginal mucosa.
  • Persistent severe dermatitis.
  • Systemic hypersensitivity requiring medical attention.

Precautions & Warnings

Use Naxyl only as prescribed and follow the recommended duration of therapy.

  • Hypersensitivity: avoid if known allergy to dequalinium chloride or similar compounds.
  • Pregnancy: consult a healthcare professional before use; safety not established.
  • Breastfeeding: discuss with a physician as data are limited.
  • Severe vaginal inflammation: do not use until inflammation resolves.
  • Concurrent vaginal products: avoid using other antiseptics or douches simultaneously.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Dequalinium chloride may interact with other intravaginal agents.

Major Interactions (Avoid)

  • Concurrent use of other vaginal antiseptics or disinfectants.
  • Simultaneous application of spermicidal products.
  • Use with vaginal douches or cleansing solutions.

Moderate Interactions (Monitor Closely)

  • Co‑administration with hormonal contraceptives (possible irritation affecting absorption).
  • Use alongside vaginal moisturizers or lubricants.
  • Presence of intravaginal devices (e.g., diaphragms) during treatment.

Frequently Asked Questions

Naxyl is an intravaginal antiseptic containing dequalinium chloride. It is used to treat vaginal infections, including bacterial vaginosis, by reducing the number of pathogenic microorganisms and helping restore a healthy vaginal flora.

Dequalinium chloride acts by inserting into microbial cell membranes, disrupting their integrity. This leads to rapid cell death of bacteria, fungi and protozoa present in the vagina, thereby controlling infection without significant systemic absorption.

The dosage regimen for Naxyl is determined by the prescribing healthcare professional based on the specific condition and patient factors. Patients should follow the instructions provided by their clinician and the product label.

Safety data for dequalinium chloride during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the potential risks and benefits with their healthcare provider before using Naxyl.

To order Naxyl, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naxyl’s active ingredient, dequalinium chloride, offers a broad spectrum of antimicrobial activity against bacteria, fungi and protozoa. Compared with some other vaginal antiseptics, it provides a non‑antibiotic option that reduces the risk of resistance while effectively managing bacterial vaginosis and related infections.

Store Naxyl at room temperature, below 25 °C, in its original packaging. Protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged.

Naxyl is applied intravaginally as directed by a healthcare professional. The product is typically inserted into the vagina using the supplied applicator or as instructed, ensuring proper placement for optimal antimicrobial effect.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, ulceration of the vaginal mucosa, and persistent severe dermatitis. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, extensive swelling, or intense pain.

Individuals with a known hypersensitivity to dequalinium chloride or any component of the formulation should avoid Naxyl. It is also contraindicated in patients with severe vaginal inflammation until the condition resolves, and it should be used with caution in pregnancy or breastfeeding after medical consultation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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