Product image of Nazar (Naphazoline Nitrate) supplied by GNH India

Nazar

Active Ingredient:
Naphazoline Nitrate
Origin:
EU

Nazar (Naphazoline Nitrate)

Naphazoline nitrate, the active ingredient in Nazar, is an alpha‑adrenergic agonist (imidazoline derivative) presented as a nasal formulation for nasal use. It relieves nasal congestion associated with the common cold, allergic rhinitis and sinusitis in adults and children.

GNH India supplies Nazar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pietrasanta Pharma S.P.A.

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Indications & Clinical Uses

Nazar acts as a topical nasal decongestant to reduce swelling of the nasal mucosa.

  • Nasal congestion due to common cold: provides rapid relief of blocked nose and improves airflow.
  • Allergic rhinitis: diminishes swelling caused by allergens, easing breathing and reducing nasal discharge.
  • Sinusitis: helps clear sinus passages by decreasing mucosal edema, supporting drainage and comfort.

How It Works

  • Naphazoline nitrate selectively stimulates alpha‑adrenergic receptors on the smooth muscle of nasal mucosal blood vessels. This activation causes vasoconstriction, which reduces blood flow, limits edema, and opens the nasal airway, thereby alleviating congestion.

Side Effects

Nazar may cause local and systemic reactions after nasal administration.

Common Side Effects

  • Burning or stinging sensation in the nose.
  • Nasal dryness or irritation.
  • Sneezing shortly after use.
  • Mild headache.

Serious or Rare Side Effects

  • Rebound congestion (rhinitis medicamentosa) with prolonged use.
  • Elevated blood pressure or tachycardia.
  • Cardiac arrhythmias in susceptible individuals.

Precautions & Warnings

Before using Nazar, consider the following safety measures.

  • Prolonged use: limit to no more than three consecutive days to avoid rebound congestion.
  • Hypertension: use with caution and monitor blood pressure.
  • Glaucoma: avoid if you have narrow‑angle glaucoma.
  • Pregnancy and breastfeeding: safety not established; consult a healthcare professional.
  • Children under 6 years: not recommended without medical advice.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Nazar can interact with other sympathomimetic agents and certain systemic medications.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may potentiate hypertensive effects.
  • Non‑selective beta‑blockers: can blunt the vasoconstrictive response and increase cardiovascular risk.

Moderate Interactions (Monitor Closely):\n- Other nasal decongestants or oral sympathomimetics: may increase systemic adrenergic activity.

  • Antihypertensive drugs: monitor blood pressure for additive effects.
  • Alcohol: may enhance dizziness or hypotensive episodes.

Frequently Asked Questions

Nazar is an over‑the‑counter nasal spray containing naphazoline nitrate. It is used to temporarily relieve nasal congestion caused by the common cold, allergic rhinitis, or sinusitis by shrinking swollen blood vessels in the nasal passages.

Naphazoline nitrate acts as a selective alpha‑adrenergic agonist. When applied to the nasal mucosa, it triggers vasoconstriction of the small blood vessels, reducing swelling and allowing air to flow more freely through the nose.

The appropriate dose of Nazar is determined by the prescribing healthcare professional. Typically, a few sprays per nostril are used, but the exact number and frequency should follow the prescriber’s instructions and the product label.

Safety data for naphazoline nitrate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Nazar to weigh potential benefits against risks.

To order Nazar, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nazar’s active ingredient, naphazoline nitrate, provides rapid vasoconstriction similar to other imidazoline decongestants like oxymetazoline. Compared with phenylephrine‑based sprays, naphazoline often offers a slightly longer duration of action but shares the same caution regarding limited‑duration use to prevent rebound congestion.

Store Nazar at room temperature, ideally below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Nazar is applied topically to each nostril using the spray pump. The user should tilt the head slightly forward, insert the tip into the nostril, and press the pump to deliver the recommended number of sprays, avoiding direct contact with the nasal mucosa.

Serious risks include rebound nasal congestion (rhinitis medicamentosa) after prolonged use, elevated blood pressure, tachycardia, and rare cardiac arrhythmias. Patients with cardiovascular disease, hypertension, or glaucoma should use Nazar only under medical supervision.

Nazar should not be used by individuals with known hypersensitivity to naphazoline nitrate or any formulation components, patients with severe hypertension, narrow‑angle glaucoma, or those who have used other nasal decongestants for more than three consecutive days without medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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