Product image of Nebivolol Cf (Nebivolol) supplied by GNH India

Nebivolol Cf

Active Ingredient:
Nebivolol
Origin:
EU

Nebivolol Cf (Nebivolol)

Nebivolol, the active ingredient in Nebivolol Cf, is a beta blocker presented as an oral tablet for oral use. It is used to lower high blood pressure in adult patients.

GNH India supplies Nebivolol Cf as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Centrafarm B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nebivolol is a selective β1‑adrenergic antagonist used in the management of elevated blood pressure and related cardiovascular conditions.

  • Hypertension: lowers systolic and diastolic blood pressure in adults.
  • Isolated systolic hypertension: reduces elevated systolic pressure while preserving diastolic values.
  • Essential hypertension: improves vascular tone and overall blood pressure control.

How It Works

  • Nebivolol selectively blocks β1‑adrenergic receptors in the heart, reducing heart rate and contractility, which lowers cardiac output. In addition, it stimulates endothelial nitric oxide release, causing vasodilation and further decreasing peripheral resistance, thereby contributing to blood pressure reduction.

Side Effects

Nebivolol may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Headache: mild to moderate pain in the head.
  • Dizziness: sensation of light‑headedness, especially on standing.
  • Fatigue: general tiredness or lack of energy.
  • Nasal congestion: blocked or runny nose.
  • Bradycardia: slower than normal heart rate.
  • Nausea: feeling of stomach upset.

Serious or Rare Side Effects

  • Severe bradycardia: markedly low heart rate requiring medical attention.
  • Symptomatic hypotension: significant drop in blood pressure causing faintness.
  • Atrioventricular block: impaired electrical conduction in the heart.
  • Bronchospasm: narrowing of airways, especially in patients with asthma.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Heart failure exacerbation: worsening of existing cardiac insufficiency.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Cardiovascular assessment: monitor heart rate and blood pressure regularly.
  • Renal impairment: evaluate kidney function and adjust therapy if needed.
  • Hepatic disease: use with caution in patients with liver dysfunction.
  • Concomitant beta‑blockers: avoid duplicate therapy to prevent excessive β‑blockade.
  • Pregnancy: safety not established; weigh risks and benefits.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Avoid Interactions

Nebivolol can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Other beta‑blockers: additive β‑blockade may cause severe bradycardia.
  • Calcium‑channel blockers (verapamil, diltiazem): increase risk of heart block and low heart rate.
  • Clonidine: abrupt discontinuation can cause rebound hypertension.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor for excessive hypotension.
  • Diuretics: watch for electrolyte disturbances and volume depletion.
  • SSRIs or other antidepressants: may affect heart rate and blood pressure control.

Frequently Asked Questions

Nebivolol Cf contains the beta‑blocker nebivolol and is prescribed to treat hypertension, helping to lower elevated systolic and diastolic blood pressure in adult patients.

Nebivolol selectively blocks β1‑adrenergic receptors in the heart, reducing heart rate and contractility, while also stimulating nitric‑oxide release from the endothelium, which causes vasodilation and further decreases peripheral vascular resistance.

The dose of nebivolol is individualized by the prescribing clinician based on the patient’s blood pressure, age, renal and hepatic function, and response to therapy. No fixed regimen is provided here.

Safety data for nebivolol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Nebivolol combines β1‑selective blockade with nitric‑oxide‑mediated vasodilation, offering blood‑pressure reduction with a lower incidence of metabolic side effects compared with non‑selective beta‑blockers. It is often considered when a patient needs both heart‑rate control and vasodilation.

Nebivolol Cf should be stored at ambient temperature, preferably below 25 °C, in its original container, protected from moisture and direct sunlight to maintain product stability.

Nebivolol Cf is taken orally, usually once daily, with or without food, as directed by a healthcare professional. Swallow the tablet whole with a glass of water.

Serious risks include severe bradycardia, symptomatic hypotension, atrioventricular block, bronchospasm in susceptible individuals, and rare allergic reactions. Patients should seek immediate medical attention if they experience fainting, rapid weight gain, or difficulty breathing.

Nebivolol is contraindicated in patients with known hypersensitivity to nebivolol or any component of the formulation, those with severe bradycardia, second‑ or third‑degree heart block without a pacemaker, and patients in cardiogenic shock.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Nebivolol

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT