Product image of Nebivolol Teva (Nebivolol) supplied by GNH India

Nebivolol Teva

Active Ingredient:
Nebivolol
Origin:
EU

Nebivolol Teva (Nebivolol)

Nebivolol, the active ingredient in Nebivolol Teva, is a beta blocker presented as an oral tablet for oral use. It is indicated for the management of hypertension and chronic heart failure in adult patients.

GNH India supplies Nebivolol Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Nebivolol belongs to the beta‑blocker class and is used to control cardiovascular conditions.
  • Hypertension: lowers systolic and diastolic blood pressure, reducing cardiovascular risk.
  • Chronic heart failure: improves left‑ventricular function and reduces symptoms of fluid overload.
  • Left‑ventricular systolic dysfunction (NYHA II‑III): enhances cardiac output and exercise tolerance.

How It Works

  • Nebivolol selectively antagonises β1‑adrenergic receptors, decreasing heart rate and myocardial contractility. In addition, it stimulates endothelial nitric oxide synthase, promoting nitric oxide release that causes vasodilation and lowers peripheral vascular resistance, thereby reducing blood pressure.

Side Effects

Nebivolol may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Headache
  • Dizziness
  • Fatigue
  • Bradycardia
  • Nausea

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm in susceptible patients
  • Allergic reactions such as rash or angioedema

Precautions & Warnings

  • Before prescribing Nebivolol, clinicians should consider several safety aspects.
  • Monitor blood pressure: ensure adequate control without excessive fall.
  • Assess cardiac function: avoid in patients with severe bradycardia or advanced AV‑node disease.
  • Use caution in asthma or chronic obstructive pulmonary disease: β‑blockade may exacerbate bronchospasm.
  • Review concomitant beta‑blocker therapy: additive effects can cause profound bradycardia.
  • Adjust in renal impairment: dose may need modification in severe dysfunction.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Nebivolol can interact with several drug classes; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid)

  • Other beta‑blockers: additive bradycardia and hypotension.
  • Verapamil or diltiazem: increased risk of AV‑node block.
  • Potent CYP2D6 inhibitors (e.g., paroxetine, fluoxetine): elevated nebivolol plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics: watch for electrolyte disturbances and excessive blood‑pressure reduction.
  • ACE inhibitors or ARBs: monitor for additive hypotensive effect.

Frequently Asked Questions

Nebivolol Teva is prescribed to lower high blood pressure (hypertension) and to treat chronic heart failure in adult patients, helping to improve cardiac function and reduce symptoms such as shortness of breath and swelling.

Nebivolol selectively blocks β1‑adrenergic receptors, which slows heart rate and reduces contractility. It also stimulates nitric oxide release from the endothelium, causing blood‑vessel relaxation and decreasing peripheral resistance, together lowering blood pressure.

The exact dose of Nebivolol Teva is determined by the prescribing clinician based on the patient’s condition, response, and any comorbidities. Dosage adjustments are made according to clinical guidelines and individual tolerance.

The safety of nebivolol in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nebivolol is a highly selective β1‑blocker that also enhances nitric oxide‑mediated vasodilation, which can provide better blood‑pressure control with fewer metabolic side effects compared with non‑selective beta‑blockers. Its dual action may be advantageous in patients who need both heart‑rate reduction and improved endothelial function.

Nebivolol Teva tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

Nebivolol Teva is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed by a healthcare provider.

Serious risks include marked bradycardia, severe hypotension, heart block, and bronchospasm in patients with reactive airway disease. Patients should be monitored for these events, especially when initiating therapy or adjusting doses.

Nebivolol is contraindicated in patients with severe bradycardia, second‑ or third‑degree atrioventricular block, cardiogenic shock, and in those with known hypersensitivity to nebivolol or any of its excipients. Caution is also advised for individuals with uncontrolled asthma or severe chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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