Product image of Nebivolol Teva (Nebivolol) supplied by GNH India

Nebivolol Teva

Active Ingredient:
Nebivolol
Origin:
EU

Nebivolol Teva (Nebivolol)

Nebivolol, the active ingredient in Nebivolol Teva, is a beta‑blocker presented as an oral tablet for oral use. It treats essential hypertension and chronic heart failure in adults.

GNH India supplies Nebivolol Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Uk Limited

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Indications & Clinical Uses

  • Nebivolol acts on the cardiovascular system to lower blood pressure and improve cardiac function.
  • Essential hypertension: reduces systolic and diastolic blood pressure, helping to control primary hypertension.
  • Chronic heart failure: improves left‑ventricular ejection fraction and reduces symptoms such as dyspnea.
  • Left‑ventricular systolic dysfunction: enhances cardiac output and may lower the risk of hospitalization.

How It Works

  • Nebivolol selectively blocks β1‑adrenergic receptors in the heart, decreasing heart rate and myocardial contractility. In addition, it stimulates endothelial nitric‑oxide release, causing vasodilation and lowering peripheral vascular resistance. The combined effect results in reduced cardiac workload and lowered arterial pressure.

Side Effects

Nebivolol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache
  • Dizziness
  • Fatigue
  • Bradycardia
  • Nausea
  • Insomnia

Serious or Rare Side Effects

  • Severe bradycardia or heart block
  • Marked hypotension
  • Bronchospasm in patients with reactive airway disease
  • Allergic skin reactions or angioedema
  • Hepatic enzyme elevation
  • Acute heart failure decompensation

Precautions & Warnings

  • Nebivolol should be used with clinical vigilance in several situations.
  • Monitor blood pressure: ensure adequate control without excessive drop.
  • Assess heart rate: avoid severe bradycardia.
  • Use caution in asthma or COPD: β1‑selectivity may still affect bronchial tone.
  • Review renal and hepatic function: dose adjustment may be needed.
  • Avoid abrupt discontinuation: taper to prevent rebound hypertension.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Nebivolol can interact with other medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Concomitant use with other β‑blockers or non‑selective β‑blockers may cause excessive cardiac depression.
  • Calcium‑channel blockers such as verapamil or diltiazem can increase AV‑node conduction delay.
  • Potent CYP2D6 inhibitors (e.g., paroxetine, fluoxetine) may raise nebivolol plasma levels.

Moderate Interactions (Monitor Closely)

  • NSAIDs may blunt the antihypertensive effect.
  • Diuretics can potentiate hypotension and electrolyte disturbances.

Frequently Asked Questions

Nebivolol Teva is prescribed for adults with essential hypertension and for patients with chronic heart failure. In hypertension, it helps lower blood pressure, while in heart failure it improves cardiac output and reduces symptoms such as shortness of breath.

Nebivolol selectively blocks β1‑adrenergic receptors in the heart, decreasing heart rate and contractility. It also stimulates endothelial nitric‑oxide release, causing vasodilation. The combined actions lower peripheral resistance and arterial pressure.

The exact dose of Nebivolol Teva is determined by the prescribing clinician based on the patient’s condition, response, and any comorbidities. Dosage may be adjusted during treatment to achieve optimal blood‑pressure control or heart‑failure management.

Safety data for nebivolol in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nebivolol is a β1‑selective blocker with additional nitric‑oxide‑mediated vasodilation, which may result in fewer metabolic side effects compared with non‑selective beta‑blockers. Its dual mechanism can offer better blood‑pressure control while preserving endothelial function.

Nebivolol Teva tablets should be stored at room temperature, below 25 °C, in the original packaging. Keep the container tightly closed and protect it from moisture and direct sunlight to maintain product stability.

Nebivolol Teva is taken orally, usually once daily with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious risks include severe bradycardia, marked hypotension, heart block, bronchospasm in patients with reactive airway disease, and rare allergic reactions such as angioedema. Patients should seek immediate medical attention if they experience these symptoms.

Nebivolol is contraindicated in patients with known hypersensitivity to nebivolol or any excipients, in those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, and in patients with uncompensated heart failure. Caution is also advised for individuals with asthma or severe chronic obstructive pulmonary disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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