Product image of Nebivololo E Idroclorotiazide Teva Italia (Hydrochlorothiazide, Nebivolol) supplied by GNH India

Nebivololo E Idroclorotiazide Teva Italia

Active Ingredient:
Hydrochlorothiazide, Nebivolol
Origin:
EU

Nebivololo E Idroclorotiazide Teva Italia (Hydrochlorothiazide, Nebivolol)

Nebivolol, the active ingredient in Nebivololo E Idroclorotiazide Teva Italia, is a beta blocker presented as an oral tablet for oral use. It treats hypertension, often in combination with hydrochlorothiazide, and is prescribed for adult patients who need both β1‑adrenergic blockade and diuretic action.

GNH India supplies Nebivololo E Idroclorotiazide Teva Italia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nebivolol/Hydrochlorothiazide is used to manage hypertension, a condition characterized by elevated blood pressure.

  • Hypertension: lowers systolic and diastolic blood pressure to target levels.
  • Essential hypertension: improves overall cardiovascular risk profile.
  • Resistant hypertension (as adjunct therapy): assists in achieving blood‑pressure goals when monotherapy is insufficient.

How It Works

  • Nebivolol selectively blocks β1‑adrenergic receptors, reducing heart rate and myocardial contractility while also enhancing nitric‑oxide‑mediated vasodilation. Hydrochlorothiazide inhibits Na⁺/Cl⁻ reabsorption in the distal convoluted tubule, increasing urinary sodium and water excretion, which decreases plasma volume and peripheral resistance. The combined actions produce additive blood‑pressure reduction.

Side Effects

Common Side Effects

  • Dizziness: feeling light‑headed, especially after standing.
  • Headache: mild to moderate intensity.
  • Fatigue: reduced energy or tiredness.
  • Increased urination: more frequent bathroom visits.
  • Nausea: upset stomach or feeling of queasiness.
  • Erectile dysfunction: reduced sexual performance.

Serious or Rare Side Effects

  • Severe hypotension: dangerously low blood pressure.
  • Electrolyte imbalance: low potassium or sodium levels.
  • Acute kidney injury: sudden decline in renal function.
  • Pancreatitis: inflammation of the pancreas.
  • Allergic reactions: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Monitor blood pressure: ensure target levels are reached without excessive drop.
  • Assess renal function: check creatinine and eGFR periodically.
  • Check electrolytes: especially potassium and sodium levels.
  • Use caution in diabetes: diuretic may affect glucose control.
  • Avoid abrupt discontinuation: taper to prevent rebound hypertension.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Nebivolol/Hydrochlorothiazide may interact with several medicines.

Major Interactions (Avoid)

  • Other antihypertensives: additive blood‑pressure lowering effect.
  • NSAIDs: may reduce diuretic efficacy and impair renal function.
  • Lithium: increased lithium levels leading to toxicity.
  • Strong CYP2D6 inhibitors: raise nebivolol plasma concentrations.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: risk of hyperkalemia when combined with thiazide.
  • Digoxin: enhanced effect due to electrolyte shifts.
  • Antidiabetic drugs: possible hypoglycemia from diuretic‑induced glucose changes.

Frequently Asked Questions

Nebivololo E Idroclorotiazide Teva Italia is a prescription medication that combines nebivolol, a β1‑selective blocker, with hydrochlorothiazide, a thiazide diuretic. The combination is indicated for the treatment of hypertension, helping to lower elevated blood pressure in adult patients.

Nebivolol blocks β1‑adrenergic receptors in the heart, reducing heart rate and contractility. It also stimulates nitric‑oxide release, causing vasodilation. This dual action lowers cardiac output and peripheral resistance, contributing to blood‑pressure reduction.

The dosage is individualized by the prescribing clinician based on the patient’s blood‑pressure profile, renal function, and response to therapy. The prescriber determines the appropriate strength and frequency according to clinical guidelines.

Nebivolol and hydrochlorothiazide are generally not recommended during pregnancy unless the potential benefit outweighs the risk. Breastfeeding mothers should consult their healthcare provider, as the drugs may pass into milk and affect the infant.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑component agents, the nebivolol/hydrochlorothiazide combo offers both β‑blockade and diuretic effects in one tablet, simplifying regimens and potentially improving adherence. It may be preferred when a patient needs both heart‑rate control and volume reduction, whereas other classes like ACE inhibitors or calcium‑channel blockers work through different mechanisms.

Store the tablets at room temperature, below 25 °C, in the original container. Protect them from moisture and direct sunlight to maintain stability throughout the shelf life.

The medication is taken orally, usually once daily with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless instructed otherwise.

Serious risks include severe hypotension, electrolyte disturbances such as low potassium, acute kidney injury, and rare allergic reactions. Patients should seek immediate medical attention if they experience fainting, muscle weakness, irregular heartbeat, severe swelling, or signs of an allergic response.

The product is contraindicated in patients with known hypersensitivity to nebivolol, hydrochlorothiazide, or any excipients, as well as those with severe renal impairment, uncontrolled electrolyte imbalances, or a history of severe hypotension. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.