Product image of Nefopam Hydrochloride Tillomed Laboratories (Nefopam Hydrochloride) supplied by GNH India

Nefopam Hydrochloride Tillomed Laboratories

Active Ingredient:
Nefopam Hydrochloride
Origin:
EU

Nefopam Hydrochloride Tillomed Laboratories (Nefopam Hydrochloride)

Nefopam Hydrochloride, the active ingredient in Nefopam Hydrochloride Tillomed Laboratories, is a non‑opioid analgesic presented as an oral formulation for oral use. It is used to manage moderate acute pain, post‑operative pain and musculoskeletal pain in adult patients.

GNH India supplies Nefopam Hydrochloride Tillomed Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tillomed Laboratories Ltd

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nefopam Hydrochloride is indicated for pain conditions that involve the central nervous system pathways of serotonin, norepinephrine and dopamine.

  • Moderate acute pain: Provides analgesia for short‑term moderate intensity pain.
  • Post‑operative pain: Reduces pain following surgical procedures.
  • Musculoskeletal pain: Alleviates pain associated with muscle and joint disorders.

How It Works

  • Nefopam Hydrochloride inhibits the reuptake of serotonin, norepinephrine and dopamine while also blocking voltage‑gated sodium channels. This multimodal action reduces neuronal excitability in the central nervous system, leading to analgesic effects without engaging opioid receptors.

Side Effects

Nefopam Hydrochloride may cause a range of adverse reactions, which are classified by frequency.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Dry mouth: reduced salivation.
  • Sweating: increased perspiration.
  • Dizziness: light‑headed sensation.
  • Blurred vision: temporary visual disturbance.
  • Constipation: difficulty passing stool.

Serious or Rare Side Effects

  • Seizures: rare occurrence of convulsive episodes.
  • Severe hypotension: marked drop in blood pressure.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Anaphylaxis: life‑threatening allergic reaction.
  • Stevens‑Johnson syndrome: severe skin reaction.
  • Blood dyscrasias: abnormal blood cell counts.

Precautions & Warnings

Before prescribing Nefopam Hydrochloride, clinicians should consider several precautionary measures.

  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor blood pressure: watch for hypotensive episodes.
  • Avoid in seizure disorders: risk of provoking seizures.
  • Use caution in elderly: increased sensitivity to side effects.
  • Do not discontinue abruptly: taper if long‑term therapy is needed.
  • Store at room temperature: keep in original packaging, protect from moisture.

Avoid Interactions

Nefopam Hydrochloride can interact with other medicines, affecting its safety or efficacy.

Major Interactions (Avoid)

  • Selective serotonin reuptake inhibitors (SSRIs): risk of serotonin syndrome.
  • Monoamine oxidase inhibitors (MAOIs): increased serotonergic activity.
  • Tricyclic antidepressants: additive central nervous system effects.

Moderate Interactions (Monitor Closely)

  • Cytochrome P450 inhibitors (e.g., fluoxetine): may increase plasma levels.
  • Cytochrome P450 inducers (e.g., carbamazepine): may reduce effectiveness.
  • Antihypertensive agents: potential additive blood pressure lowering.

Frequently Asked Questions

Nefopam Hydrochloride is a non‑opioid analgesic indicated for the relief of moderate acute pain, post‑operative pain, and musculoskeletal pain. It is prescribed for adult patients when opioid therapy is not required or when a different mechanism of pain control is desired.

The drug works by inhibiting the reuptake of the neurotransmitters serotonin, norepinephrine and dopamine, and by blocking sodium channels in the central nervous system. This combined effect reduces neuronal excitability and modulates pain signaling without acting on opioid receptors.

The appropriate dose of Nefopam Hydrochloride is determined by the prescribing healthcare professional based on the individual patient's condition, severity of pain, and response to therapy. Specific dosing regimens are not provided here and should follow the prescriber’s instructions.

Safety data for Nefopam Hydrochloride in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with NSAIDs, Nefopam does not inhibit cyclo‑oxygenase enzymes and therefore carries a lower risk of gastrointestinal bleeding. Unlike opioids, it does not cause respiratory depression or dependence, but it may cause central nervous system side effects such as dizziness or seizures in susceptible individuals.

Store the product at room temperature, preferably below 25 °C. Keep it in the original container, protect it from moisture and direct sunlight, and ensure the packaging remains sealed until use.

Nefopam Hydrochloride is administered orally. It can be taken with or without food, according to the prescriber’s guidance, and should be swallowed whole with an adequate amount of water.

The most serious adverse reactions include seizures, severe hypotension, cardiac arrhythmias, and life‑threatening allergic responses such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be monitored for these events, especially when taking interacting medications.

Nefopam should be avoided in patients with a known hypersensitivity to the drug, a history of seizure disorders, uncontrolled hypertension, or those currently receiving MAO inhibitors or SSRIs without appropriate medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Nefopam Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT