Neiratax (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride)

Neiratax addresses vitamin B deficiency disorders and provides local anesthesia for minor interventions.

• Thiamine (vitamin B1) deficiency: restores normal carbohydrate metabolism and prevents neurological complications.
• Cyanocobalamin (vitamin B12) deficiency: supports red blood cell formation and neurological function.
• Pyridoxine (vitamin B6) deficiency: aids amino‑acid metabolism and hemoglobin synthesis.
• Minor procedural anesthesia: produces temporary loss of sensation for short, superficial surgeries or diagnostic procedures.

• The thiamine, cyanocobalamin and pyridoxine components act as essential co‑enzymes in carbohydrate metabolism, hematopoiesis and amino‑acid processing, facilitating energy production and red blood cell formation. Lidocaine binds to voltage‑gated sodium channels on neuronal membranes, stabilising the inactive state and preventing depolarisation, thereby blocking nerve impulse transmission and producing local anaesthesia.

Neiratax may cause a range of adverse reactions following intramuscular administration.

Common Side Effects

• Injection site pain or tenderness.
• Redness or mild swelling at the injection site.
• Transient dizziness or light‑headedness.
• Nausea or mild gastrointestinal upset.
• Headache.
• Temporary tingling or numbness near the injection area.

Serious or Rare Side Effects

• Anaphylactic or severe allergic reaction.
• Marked hypotension or cardiovascular collapse.
• Cardiac arrhythmias or conduction disturbances.
• Seizures or central nervous system depression.
• Persistent numbness or motor weakness.
• Severe skin reactions such as Stevens‑Johnson syndrome.

Before administering Neiratax, consider the following safety measures.

• Assess vitamin B status: evaluate baseline levels to avoid unnecessary supplementation.
• Monitor for hypersensitivity: observe patients for signs of allergic reaction during and after injection.
• Use with caution in cardiac conduction disorders: lidocaine may exacerbate arrhythmias.
• Avoid in patients with known lidocaine allergy: substitute with an alternative anesthetic.
• Adjust dose in renal or hepatic impairment: impaired metabolism may increase systemic exposure.
• Store at ambient temperature: keep in original container, protect from moisture and light.

Neiratax can interact with several medicines; awareness of major and moderate interactions helps minimise risk.

Major Interactions (Avoid)

• Concurrent other local anesthetics: cumulative toxicity risk.
• Monoamine oxidase inhibitors: may enhance hypotensive effect.
• Class I antiarrhythmic agents (e.g., quinidine): increase lidocaine plasma levels.
• High‑dose vitamin B supplements: potential masking of deficiency symptoms.
• Strong CYP450 inhibitors: reduce lidocaine metabolism, raising toxicity.

Moderate Interactions (Monitor Closely)

• Beta‑blockers: may potentiate bradycardia.
• Diuretics: can alter electrolyte balance affecting lidocaine action.
• Alcohol: may increase central nervous system depression.
• Anticonvulsants: may modify pyridoxine metabolism.
• NSAIDs: possible increased bleeding tendency.