Product image of Neiraxin B (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride) supplied by GNH India

Neiraxin B

Active Ingredient:
Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride
Origin:
EU

Neiraxin B (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride)

Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, and Lidocaine Hydrochloride, the active ingredients in Neiraxin B, are a vitamin B complex and local anesthetic presented as an intramuscular injection for intramuscular use. It addresses vitamin B deficiencies and provides local anesthesia for the injection site.

GNH India supplies Neiraxin B as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Kalceks

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Indications & Clinical Uses

Neiraxin B is used to correct vitamin B complex deficiencies and to provide local anesthesia during intramuscular administration.

  • Vitamin B1 deficiency (Thiamine deficiency): restores thiamine levels and supports carbohydrate metabolism.
  • Vitamin B6 deficiency (Pyridoxine deficiency): corrects pyridoxine shortage and aids neurotransmitter synthesis.
  • Vitamin B12 deficiency (Cyanocobalamin deficiency): replenishes cobalamin stores and assists red blood cell formation.
  • Procedural pain control: lidocaine provides temporary numbness at the injection site.

How It Works

  • Thiamine acts as a co‑factor for enzymes involved in carbohydrate metabolism, pyridoxine serves as a co‑factor for amino‑acid and neurotransmitter synthesis, and cyanocobalamin participates in methylmalonyl‑CoA mutase activity and DNA synthesis. Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, inhibiting impulse propagation and producing local anesthesia. Together, the vitamins correct specific deficiencies while lidocaine ensures a painless intramuscular delivery.

Side Effects

Common Side Effects

  • Injection site pain or tenderness.
  • Mild erythema or swelling at the site.
  • Transient headache.
  • Nausea or mild gastrointestinal upset.
  • Dizziness or light‑headedness.
  • Tingling or paraesthesia near the injection area.

Serious or Rare Side Effects

  • Allergic reaction including rash, pruritus, or angioedema.
  • Anaphylaxis requiring emergency treatment.
  • Severe hypotension or cardiovascular collapse.
  • Cardiac arrhythmias linked to lidocaine toxicity.
  • Methemoglobinemia.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before administration, consider the following precautions:

  • Assess vitamin B status: ensure deficiency exists before supplementation.
  • Monitor for hypersensitivity: discontinue if allergic signs appear.
  • Avoid in patients with known lidocaine allergy.
  • Use with caution in hepatic or renal impairment due to altered metabolism.
  • Do not exceed recommended vitamin doses to prevent neuropathy.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Neiraxin B may interact with other medicines as follows:

Major Interactions (Avoid)

  • Concurrent use of other local anesthetics: increased risk of systemic toxicity.
  • High‑dose vitamin B supplements: may precipitate peripheral neuropathy.
  • MAO inhibitors combined with lidocaine: heightened central nervous system toxicity.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: may increase bleeding at the injection site.
  • Diuretics: can affect electrolyte balance when combined with pyridoxine.
  • Alcohol consumption: may exacerbate hepatic load from high vitamin doses.

Frequently Asked Questions

Neiraxin B is an injectable combination of thiamine, cyanocobalamin, pyridoxine and lidocaine. It is employed to correct deficiencies of vitamins B1, B6 and B12 and to provide local anesthesia during the intramuscular injection, helping manage deficiency‑related conditions and procedural discomfort.

Each vitamin acts as a co‑factor for essential metabolic pathways: thiamine supports carbohydrate metabolism, pyridoxine assists amino‑acid and neurotransmitter synthesis, and cyanocobalamin is required for DNA synthesis and red‑cell formation. Lidocaine blocks sodium channels, preventing nerve impulse transmission and producing temporary numbness at the injection site.

The dosage of Neiraxin B is determined by the prescribing healthcare professional based on the patient’s clinical condition, vitamin status and procedural requirements. Only a qualified prescriber should set the appropriate dose and administration schedule.

Safety data for Neiraxin B in pregnancy and lactation are limited. The benefits and risks should be evaluated by the treating physician. Generally, vitamin B supplementation may be indicated, but lidocaine exposure should be considered carefully, especially in the first trimester.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and the necessary import documentation.

Neiraxin B combines three B‑vitamins with a local anesthetic in a single intramuscular formulation, offering both deficiency correction and immediate pain control. Other vitamin B injections may contain only one or two vitamins and lack an anesthetic, requiring separate analgesia for painful administrations.

Neiraxin B should be stored at ambient temperature, protected from direct sunlight, moisture and extreme heat. Keep the vial in its original packaging until use and avoid freezing. Inspect the product for particulate matter before administration.

Neiraxin B is given by intramuscular injection into a suitable muscle group, typically the deltoid or gluteal region. The injection should be performed by a qualified healthcare professional using aseptic technique and appropriate needle size.

Serious risks include severe allergic reactions such as anaphylaxis, cardiovascular collapse or arrhythmias from lidocaine toxicity, and rare hematologic disorders like methemoglobinemia. Immediate medical attention is required if any of these symptoms occur.

Neiraxin B is contraindicated in individuals with known hypersensitivity to any of its components, especially lidocaine, or in patients with severe hepatic or renal impairment where vitamin metabolism is compromised. It should also be avoided in patients with certain cardiac conduction disorders when high doses of lidocaine are used.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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