Product image of Neiraxin (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride) supplied by GNH India

Neiraxin

Active Ingredient:
Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride
Origin:
EU

Neiraxin (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, Lidocaine Hydrochloride)

Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride, and Lidocaine Hydrochloride, the active ingredients in Neiraxin, are a multivitamin and local‑anesthetic combination presented as a sterile injectable solution for intramuscular use. It is employed to correct B‑vitamin deficiencies and to provide temporary analgesia during procedures.
GNH India supplies Neiraxin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Kalceks

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Indications & Clinical Uses

Neiraxin is used as a multicomponent injection that addresses vitamin deficiencies and provides local analgesia.

  • Vitamin B1 (thiamine) deficiency: restores carbohydrate metabolism in patients with thiamine shortage.
  • Vitamin B12 (cyanocobalamin) deficiency: supports hematologic and neurologic function in deficient individuals.
  • Vitamin B6 (pyridoxine) deficiency: aids amino‑acid metabolism and reduces related neuropathic symptoms.
  • Procedural pain relief: lidocaine component delivers short‑term local anesthesia for intramuscular interventions.

How It Works

  • Thiamine acts as a co‑factor for enzymes in carbohydrate metabolism, cyanocobalamin participates in DNA synthesis and neurologic maintenance, and pyridoxine is essential for neurotransmitter synthesis and amino‑acid metabolism. Lidocaine blocks voltage‑gated sodium channels in neuronal membranes, preventing depolarisation and producing reversible local anaesthesia. Together the components correct metabolic deficits while providing analgesia at the injection site.

Side Effects

Neiraxin may cause a range of adverse reactions following intramuscular administration.

Common Side Effects

  • Injection site pain or erythema
  • Mild nausea or vomiting
  • Headache or dizziness
  • Transient hypotension
  • Localised swelling or bruising
  • Mild pruritus

Serious or Rare Side Effects

  • Anaphylactic reaction or severe hypersensitivity
  • Cardiovascular collapse or severe arrhythmia
  • Persistent neurological deficits
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Serum vitamin toxicity (rare with high cumulative doses)
  • Severe local tissue necrosis

Precautions & Warnings

Before using Neiraxin, clinicians should consider several safety measures.

  • Assess vitamin status: confirm deficiency before administration.
  • Monitor for hypersensitivity: observe for rash, itching or respiratory distress.
  • Avoid in patients with known lidocaine allergy: substitute with an alternative anaesthetic.
  • Use caution in cardiac conduction disorders: lidocaine may affect heart rhythm.
  • Adjust for renal or hepatic impairment: consider reduced clearance of vitamins.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Neiraxin can interact with other agents, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Concurrent use of other local anaesthetics: risk of cumulative lidocaine toxicity.
  • High‑dose vitamin B supplements: may lead to hypervitaminosis.
  • MAO inhibitors: potential for hypertensive episodes when combined with lidocaine.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask lidocaine‑induced cardiovascular effects.
  • Anticoagulants: vitamin K pathway not directly involved, but monitor bleeding risk if large volumes are injected.
  • Diuretics: may alter electrolyte balance affecting lidocaine activity.

Frequently Asked Questions

Neiraxin is a sterile intramuscular injection that combines thiamine, cyanocobalamin, pyridoxine and lidocaine. It is used to correct deficiencies of the B‑vitamins thiamine (B1), cyanocobalamin (B12) and pyridoxine (B6) while providing short‑term local analgesia for procedures that require intramuscular administration.

Each vitamin component serves as a co‑factor in essential metabolic pathways: thiamine supports carbohydrate metabolism, cyanocobalamin is required for DNA synthesis and neurologic health, and pyridoxine participates in amino‑acid and neurotransmitter synthesis. Lidocaine, the anesthetic part, blocks voltage‑gated sodium channels, preventing nerve impulse transmission and producing temporary pain relief at the injection site.

The specific dose and frequency of Neiraxin are determined by the prescribing clinician based on the patient’s vitamin status, clinical condition and procedural needs. Healthcare professionals should follow local prescribing guidelines and adjust the regimen according to individual therapeutic response and safety considerations.

Safety data for Neiraxin in pregnancy and lactation are limited. The decision to use the product should be made by a qualified healthcare provider after weighing potential benefits against possible risks to the mother and fetus or infant. Generally, B‑vitamin supplementation may be indicated in deficiency, but lidocaine exposure should be evaluated carefully.

To place an order, submit an enquiry on the Neiraxin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Neiraxin uniquely combines three B‑vitamins with a local anesthetic in a single intramuscular formulation, offering both deficiency correction and procedural analgesia. Other vitamin‑B injections typically contain only one or two vitamins and lack an anesthetic component, so they do not provide the same immediate pain‑relief benefit during intramuscular procedures.

Neiraxin should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight and extreme temperature fluctuations. Do not freeze the solution, and inspect the vial for particulate matter before administration.

Neiraxin is administered by a qualified healthcare professional via intramuscular injection. The injection site should be prepared with aseptic technique, and the recommended volume is injected slowly to minimise discomfort. The exact injection site and volume depend on the clinical indication and patient characteristics.

The most serious risks include severe allergic reactions such as anaphylaxis, cardiovascular collapse or arrhythmias due to lidocaine toxicity, and rare cases of severe skin reactions like Stevens‑Johnson syndrome. Prompt recognition and emergency management are essential if any of these events occur.

Neiraxin should be avoided in individuals with a known hypersensitivity to any of its components, especially lidocaine. Patients with severe cardiac conduction disorders, uncontrolled hypotension, or those receiving high‑dose vitamin B supplementation without medical supervision should also be evaluated carefully before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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