Product image of Neladap (Adapalene, Benzoyl Peroxide) supplied by GNH India

Neladap

Active Ingredient:
Adapalene, Benzoyl Peroxide
Origin:
EU

Neladap (Adapalene, Benzoyl Peroxide)

Adapalene and benzoyl peroxide, the active ingredients in Neladap, are a retinoid and a keratolytic/antibacterial presented as a topical formulation for topical use. They are indicated for the treatment of acne vulgaris in adolescents and adults, helping to reduce comedones, inflammation and bacterial colonisation.\n\nGNH India supplies Neladap as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glenmark Pharmaceuticals S.R.O.

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Indications & Clinical Uses

  • Neladap is a topical acne medication that acts on the pilosebaceous unit to improve skin lesions.\n\nAcne vulgaris: reduces the number of inflammatory and non‑inflammatory lesions.\nMild to moderate acne: helps clear existing pimples and prevents new ones.\nComedonal acne: decreases formation of blackheads and whiteheads.

How It Works

  • Adapalene binds to retinoic acid receptors in keratinocytes, normalising differentiation and exerting anti‑inflammatory effects. Benzoyl peroxide releases free radical oxygen that oxidises bacterial proteins, providing antibacterial activity against Propionibacterium acnes and promoting keratolysis. The combined actions reduce follicular hyperkeratinisation, bacterial overgrowth and inflammation, thereby limiting comedogenesis.

Side Effects

  • Neladap may cause local skin reactions, most of which are mild and transient.\n\nCommon Side Effects:\n- Dryness or peeling of the skin\n- Redness or mild irritation\n- Burning or stinging sensation\n- Itching\n- Increased sensitivity to sunlight\n- Temporary worsening of acne during initial use\n\nSerious or Rare Side Effects:\n- Severe allergic reaction (e.g., swelling, hives)\n- Persistent or worsening irritation\n- Contact dermatitis\n- Hyperpigmentation in susceptible individuals\n- Ocular irritation if product contacts eyes\n- Unusual skin discoloration

Precautions & Warnings

  • Before using Neladap, consider the following safety measures.\n\nAvoid excessive sun exposure: use sunscreen and protective clothing.\nDo not apply to broken or inflamed skin: wait until lesions heal.\nLimit use on sensitive areas: avoid eyes, lips and mucous membranes.\nDiscontinue if severe irritation occurs: consult a healthcare professional.\nPregnancy and breastfeeding: discuss risks with a clinician before use.\nStore at ambient temperature: keep below 25°C in the original container, protect from moisture and direct light.

Avoid Interactions

  • Neladap can interact with other topical or systemic agents that affect skin integrity.\n\nMajor Interactions (Avoid):\n- Concurrent use of other retinoids (e.g., tretinoin) – may increase irritation.\n- Strong topical steroids applied to the same area – may reduce efficacy.\n\nModerate Interactions (Monitor Closely):\n- Salicylic acid or other keratolytics – may enhance dryness.\n- Antibacterial soaps or cleansers – may increase skin sensitivity.\n- Systemic isotretinoin – overlapping retinoid effects may increase adverse skin reactions.

Frequently Asked Questions

Neladap is a topical medication indicated for the treatment of acne vulgaris. It helps reduce inflammatory and non‑inflammatory lesions by combining the actions of adapalene, a retinoid, and benzoyl peroxide, an antibacterial and keratolytic agent.

Adapalene binds to retinoic acid receptors in skin cells, normalising keratinocyte differentiation and exerting anti‑inflammatory effects. This reduces follicular plugging and the formation of comedones, contributing to clearer skin.

The dosing regimen for Neladap is determined by the prescribing healthcare professional. Typically, a thin layer is applied once daily to the affected areas, but the exact amount and frequency should follow the prescriber’s instructions.

Safety of Neladap in pregnancy or while breastfeeding has not been fully established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using the product.

To order Neladap, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neladap combines a retinoid (adapalene) with benzoyl peroxide, offering both anti‑inflammatory and antibacterial actions in a single formulation. Compared with single‑agent products, this dual mechanism can provide broader efficacy while simplifying the treatment regimen.

Neladap should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Neladap is applied topically to clean, dry skin. A thin layer is spread over the affected areas, usually once daily in the evening, unless otherwise directed by a healthcare professional. Hands should be washed after application.

Serious risks, though rare, include severe allergic reactions such as swelling, hives, or difficulty breathing, and persistent or worsening skin irritation. If any of these occur, discontinue use immediately and seek medical attention.

Individuals with known hypersensitivity to adapalene, benzoyl peroxide, or any excipients in the formulation should avoid using Neladap. It is also contraindicated on broken, inflamed, or infected skin and should be used with caution in pregnancy or lactation after medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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