Product image of Neo Borocillina Fluidificante Tosse (Ambroxol Hydrochloride) supplied by GNH India

Neo Borocillina Fluidificante Tosse

Active Ingredient:
Ambroxol Hydrochloride
Origin:
EU

Neo Borocillina Fluidificante Tosse (Ambroxol Hydrochloride)

Ambroxol Hydrochloride, the active ingredient in Neo Borocillina Fluidificante Tosse, is a mucolytic presented as an oral formulation for oral use. It helps to loosen thick mucus in the airways, facilitating expectoration in patients with productive coughs and related respiratory conditions, and is indicated for use in adults and children.

GNH India supplies Neo Borocillina Fluidificante Tosse as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare providers worldwide.

Manufacturer / TM Owner

Alfasigma S.P.A.

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Indications & Clinical Uses

Ambroxol is a mucolytic that acts on respiratory secretions to improve clearance in several common airway conditions.

  • Productive cough: reduces mucus viscosity, aiding expectoration.
  • Acute bronchitis: facilitates mucus clearance, helping relieve cough.
  • Upper respiratory tract infections: assists in thinning secretions, supporting symptom relief.

How It Works

  • Ambroxol hydrochloride increases serous secretion from bronchial glands and depolymerizes mucopolysaccharide fibers in mucus, thereby lowering its viscosity. The resulting thinner secretions are more easily transported by ciliary action and coughing, enhancing mucociliary clearance. Its action is localized to the respiratory tract and does not involve systemic anti‑inflammatory pathways.

Side Effects

Ambroxol may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Altered taste, often described as bitter or salty.
  • Nausea or mild gastrointestinal discomfort.
  • Diarrhea or loose stools.

Serious or Rare Side Effects

  • Allergic reactions such as rash, urticaria or angioedema.
  • Severe skin reactions including Stevens‑Johnson syndrome.
  • Hepatic enzyme elevations or liver dysfunction.

Precautions & Warnings

When using Ambroxol, certain precautions should be observed to ensure safe and effective therapy.

  • Pediatric use: dosage and duration should follow prescriber guidance, especially in children under two years.
  • Hepatic impairment: consider reduced dosing or monitoring in patients with liver disease.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Asthma: monitor for bronchospasm, although rare, in patients with reactive airway disease.
  • Concomitant mucolytics: avoid simultaneous use of multiple mucolytic agents without medical advice.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and direct sunlight in the original packaging.

Avoid Interactions

Ambroxol can interact with other medicines, and the nature of the interaction determines the level of monitoring required.

Major Interactions (Avoid)

  • Combined use with other mucolytic agents (e.g., N‑acetylcysteine) may increase risk of bronchospasm.
  • Concomitant administration with known hypersensitivity‑inducing drugs in patients with a history of allergic reactions.

Moderate Interactions (Monitor Closely)

  • Antacids may reduce oral absorption of ambroxol, potentially lowering efficacy.
  • Drugs metabolized by CYP2D6 (e.g., certain antidepressants) could have altered plasma levels, requiring observation.
  • Bronchodilators (β2‑agonists) may have additive cough‑suppressing effects; monitor therapeutic response.

Frequently Asked Questions

Neo Borocillina Fluidificante Tosse contains Ambroxol Hydrochloride, a mucolytic that is used to thin and loosen thick respiratory secretions. It helps patients with productive cough, bronchitis or upper respiratory tract infections to clear mucus more effectively and relieve coughing.

Ambroxol increases the production of serous fluid in the bronchial glands and breaks down mucopolysaccharide fibers in mucus. This reduces mucus viscosity, making it easier for ciliary action and coughing to transport the secretions out of the airways, thereby improving clearance.

The appropriate dose of Ambroxol is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of symptoms and local prescribing guidelines. Patients should follow the prescriber’s instructions and the product label.

Safety data for Ambroxol in pregnancy and lactation are limited. The product should only be used if the prescriber judges that the potential benefit outweighs any possible risk to the fetus or infant. Women who are pregnant or breastfeeding should discuss use with their healthcare provider.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ambroxol differs from simple expectorants such as guaifenesin by actively stimulating serous secretion and depolymerising mucus fibers, leading to a more pronounced reduction in viscosity. It is often preferred when thick, tenacious mucus is present, whereas other agents mainly increase the volume of airway secretions.

The product should be stored at ambient temperature, preferably below 25 °C, in its original packaging. It must be kept away from moisture, direct sunlight and sources of heat to maintain stability and potency.

Neo Borocillina Fluidificante Tosse is taken orally as directed by the prescriber. The tablet or liquid is swallowed with a glass of water, typically after meals, unless otherwise instructed. Do not crush or chew tablets unless the label specifically permits it.

Serious adverse reactions are rare but may include severe allergic responses such as rash, urticaria, angioedema, or Stevens‑Johnson syndrome, as well as liver enzyme elevations indicating hepatic involvement. Any signs of hypersensitivity or liver dysfunction should prompt immediate medical evaluation.

Individuals with a known hypersensitivity to Ambroxol or any other component of the formulation should avoid the product. Patients with severe hepatic impairment should use it only under close medical supervision, and children under the age recommended by the prescriber should not be given the medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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