Product image of Neo Borocillina Gola Dolore (Flurbiprofen) supplied by GNH India

Neo Borocillina Gola Dolore

Active Ingredient:
Flurbiprofen
Origin:
EU

Neo Borocillina Gola Dolore (Flurbiprofen)

Flurbiprofen, the active ingredient in Neo Borocillina Gola Dolore, is a nonsteroidal anti-inflammatory drug presented as an oropharyngeal formulation for local use. It is indicated for sore throat, mild to moderate oropharyngeal pain and inflammation in adults and adolescents.

GNH India supplies Neo Borocillina Gola Dolore as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alfasigma S.P.A.

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Indications & Clinical Uses

Flurbiprofen acts on inflammatory pathways of the oropharynx, providing analgesic and anti‑inflammatory benefits.

  • Sore throat (pharyngitis): reduces pain and swelling in the throat.
  • Oropharyngeal inflammation: diminishes tissue edema and discomfort.
  • Mild to moderate oropharyngeal pain: offers rapid analgesia for discomfort caused by irritation or infection.

How It Works

  • Flurbiprofen reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis limits inflammation, pain signaling, and fever generation at the site of oropharyngeal irritation.

Side Effects

Flurbiprofen may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild stomach upset after use.
  • Dyspepsia: discomfort or burning in the upper abdomen.
  • Headache: transient tension‑type headache.
  • Local irritation: transient burning sensation in the throat.

Serious or Rare Side Effects

  • Gastrointestinal ulcer or bleeding: severe stomach or intestinal lesions.
  • Allergic reaction: rash, itching, or anaphylaxis.
  • Renal impairment: reduced kidney function in susceptible individuals.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before using Neo Borocillina Gola Dolore, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcer disease.
  • Evaluate renal function: use caution in those with impaired kidney function.
  • Review concomitant NSAID or anticoagulant therapy: increased bleeding risk.
  • Check for hypersensitivity: discontinue if allergic signs appear.
  • Use the lowest effective dose for the shortest duration needed.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Flurbiprofen can interact with several medicines; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Warfarin or other anticoagulants: heightened bleeding risk.
  • SSRIs, SNRIs, or tricyclic antidepressants: increased risk of gastrointestinal bleeding.
  • Lithium: possible rise in lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of flurbiprofen.
  • ACE inhibitors or ARBs: potential for reduced renal function.
  • Corticosteroids: additive risk of ulceration and bleeding.

Frequently Asked Questions

Neo Borocillina Gola Dolore contains flurbiprofen and is intended for the local treatment of sore throat, mild to moderate oropharyngeal pain, and inflammation. It provides analgesic and anti‑inflammatory effects directly at the site of irritation in the throat.

Flurbiprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels lead to decreased inflammation, pain, and swelling in the oropharyngeal tissues.

The exact dose and frequency are determined by the prescribing healthcare professional based on the severity of symptoms, patient age, and clinical judgment. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety in pregnancy and lactation has not been fully established for flurbiprofen used in this form. Healthcare providers should weigh potential benefits against risks and consider alternative treatments when treating pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Flurbiprofen offers a potent anti‑inflammatory effect with rapid onset when applied locally to the throat, which can be advantageous over systemic NSAIDs that may require higher systemic exposure. Its topical route limits systemic side effects but still shares class‑related risks such as gastrointestinal irritation.

Neo Borocillina Gola Dolore should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and ensure it is out of reach of children.

The product is intended for oropharyngeal use. The prescribed amount is applied directly to the affected area of the throat, typically by spraying or swabbing as directed by the healthcare professional. Patients should avoid swallowing large volumes and follow the administration instructions carefully.

Serious risks include gastrointestinal ulceration or bleeding, severe allergic reactions such as anaphylaxis, renal impairment, and rare but severe skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as vomiting blood, severe rash, or sudden kidney problems.

Individuals with known hypersensitivity to flurbiprofen or any NSAID, those with active gastrointestinal ulcer disease, severe renal or hepatic impairment, and patients taking anticoagulants or other drugs that significantly increase bleeding risk should avoid using this product unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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