Product image of Neo-Botacreme (Ciclopirox Olamine) supplied by GNH India

Neo-Botacreme

Active Ingredient:
Ciclopirox Olamine
Origin:
EU

Neo-Botacreme (Ciclopirox Olamine)

Ciclopirox olamine, the active ingredient in Neo-Botacreme, is an antifungal presented as a topical cream for skin application. The formulation is designed for easy topical use and conforms to EU regulatory standards, treating fungal infections such as athlete’s foot, ringworm and yeast infections in adults and children.

GNH India supplies Neo-Botacreme as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Target Pharma Single Member Private Ltd

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Indications & Clinical Uses

Neo‑Botacreme (ciclopirox olamine) is used to treat superficial fungal infections of the skin and nails.

  • Tinea pedis: reduces itching and clears infection of the feet.
  • Tinea corporis: eliminates ring‑shaped lesions on the body.
  • Tinea cruris: resolves fungal infection of the groin area.
  • Candidiasis: treats yeast‑related skin irritation.
  • Dermatophytosis: eradicates a broad range of dermatophyte infections.

How It Works

  • Ciclopirox olamine interferes with fungal sterol synthesis, disrupting the integrity of the cell membrane and inhibiting essential enzymatic processes. This dual action impairs fungal metabolism and leads to cell death, providing broad‑spectrum activity against dermatophytes, yeasts and some molds when applied topically.

Side Effects

Adverse reactions are generally limited to the site of application.

Common Side Effects

  • Application site irritation: mild redness or discomfort.
  • Burning sensation: transient heat feeling after application.
  • Pruritus: occasional itching at the treated area.
  • Dryness: skin may become less moist.
  • Erythema: mild redness of the skin.
  • Scaling: slight flaking of the surface.

Serious or Rare Side Effects

  • Severe allergic reaction: angioedema or anaphylaxis.
  • Contact dermatitis: intense rash or swelling.
  • Systemic hypersensitivity: rare systemic immune response.
  • Bullous formation: blistering of the skin.
  • Ulceration: development of open sores at the site.

Precautions & Warnings

Before using Neo‑Botacreme, consider the following safety measures.

  • Avoid use on broken skin: limit application to intact epidermis.
  • Do not apply to eyes or mucous membranes: risk of irritation.
  • Discontinue if severe irritation occurs: seek medical advice.
  • Consult a healthcare professional before use in children under 2 years: safety not established.
  • Avoid concurrent use with other topical antifungals unless directed: may increase irritation.
  • Store below 25°C: keep in the original container, protect from moisture and heat.

Avoid Interactions

Neo‑Botacreme may interact with other topical agents.

Major Interactions (Avoid)

  • Concurrent use with other topical antifungal agents: may increase local irritation.
  • Use with corticosteroid creams: can mask signs of infection.
  • Combination with systemic antifungal therapy: potential additive toxicity (rare).

Moderate Interactions (Monitor Closely)

  • Alcohol‑based skin products: may affect drug absorption.
  • Occlusive dressings: increase local drug concentration.
  • Concomitant chemotherapeutic agents affecting skin integrity: monitor for heightened irritation.

Frequently Asked Questions

Neo‑Botacreme is a topical antifungal cream indicated for the treatment of superficial fungal skin infections such as athlete’s foot (tinea pedis), body ringworm (tinea corporis), groin infection (tinea cruris), candidal skin infections and other dermatophytoses. It is applied directly to the affected area to relieve symptoms and eradicate the fungus.

Ciclopirox olamine acts by inhibiting fungal sterol synthesis and disrupting cell‑membrane function. This dual mechanism interferes with essential enzymatic pathways, leading to loss of membrane integrity and ultimately causing fungal cell death. The effect is localized to the skin where the cream is applied.

The specific dosing regimen is determined by the prescribing healthcare professional based on the infection type, severity and patient age. Typically, a thin layer is applied to the clean, dry affected skin once or twice daily for the period recommended by the prescriber.

Safety data for ciclopirox olamine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Neo‑Botacreme.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The sales team will then respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Neo‑Botacreme (ciclopirox olamine) offers a broad spectrum of activity against dermatophytes and yeasts and is applied topically, unlike oral agents such as terbinafine or itraconazole which require systemic exposure. It is often chosen for localized infections where systemic therapy is unnecessary, providing a favorable safety profile with minimal systemic absorption.

Store Neo‑Botacreme below 25 °C in its original packaging, protecting it from moisture, direct sunlight and excessive heat. Keep the container tightly closed when not in use and avoid exposing the cream to temperatures above the recommended range to maintain product stability.

Clean and dry the affected skin area before use. Apply a thin layer of Neo‑Botacreme to the lesion and gently rub it in until it disappears. Follow the prescriber’s instructions regarding frequency and duration of treatment, and wash hands after application unless the hands are the treatment site.

While generally well tolerated, serious adverse reactions can include severe allergic responses such as angioedema, extensive contact dermatitis, or systemic hypersensitivity. If any signs of a severe reaction—such as swelling of the face, difficulty breathing, or widespread rash—appear, discontinue use and seek immediate medical attention.

Neo‑Botacreme should not be used by individuals with known hypersensitivity to ciclopirox olamine or any of the cream’s excipients. It is also contraindicated on broken skin, mucous membranes, or the eyes. Patients with severe skin disorders or those taking conflicting topical medications should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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