Product image of Neobrufen (Ibuprofen) supplied by GNH India

Neobrufen

Active Ingredient:
Ibuprofen
Origin:
EU

Neobrufen (Ibuprofen)

Ibuprofen, the active ingredient in Neobrufen, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, fever, and inflammatory conditions such as arthritis in adults and children when appropriate.
GNH India supplies Neobrufen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Healthcare Limited

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Indications & Clinical Uses

  • Ibuprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.
  • Mild to moderate pain: provides analgesic relief for headaches, dental pain, and musculoskeletal discomfort.
  • Fever: lowers elevated body temperature.
  • Inflammatory conditions such as arthritis: decreases joint swelling and improves mobility.

How It Works

  • Ibuprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may occur with ibuprofen use and are categorized by frequency.

Common Side Effects

  • Gastrointestinal upset (nausea, dyspepsia)
  • Headache
  • Dizziness
  • Mild rash or itching
  • Elevated liver enzymes
  • Mild increase in blood pressure

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe renal impairment
  • Cardiovascular events such as myocardial infarction
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Anaphylaxis or severe allergic reactions
  • Hepatotoxicity

Precautions & Warnings

  • Before using ibuprofen, consider the following safety measures.
  • Assess renal function: adjust use in patients with impaired kidney function.
  • Monitor gastrointestinal risk: avoid in individuals with a history of ulcer or bleeding.
  • Avoid concurrent anticoagulants: increased risk of hemorrhage.
  • Use caution in pregnancy: limited data, consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: potential for renal impairment.
  • Lithium: possible increase in serum lithium levels.

Frequently Asked Questions

Neobrufen contains ibuprofen, which is used to relieve mild to moderate pain, reduce fever, and manage inflammatory conditions such as arthritis. It works by decreasing the production of prostaglandins that cause pain and inflammation.

Ibuprofen blocks the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, preventing the conversion of arachidonic acid into prostaglandins. Lower prostaglandin levels reduce inflammation, alleviate pain, and lower body temperature during fever.

The appropriate dose of Neobrufen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of ibuprofen in pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only if clearly needed. Breastfeeding mothers should consult their doctor before using ibuprofen.

To order Neobrufen, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neobrufen (ibuprofen) offers a balance of analgesic, antipyretic, and anti‑inflammatory effects with a relatively short half‑life, allowing flexible dosing. Compared with stronger NSAIDs like diclofenac, ibuprofen generally has a lower risk of cardiovascular events but similar gastrointestinal considerations.

Neobrufen should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not store in areas with high humidity.

Neobrufen is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, severe kidney injury, cardiovascular events such as heart attack or stroke, and rare but severe skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of these conditions.

Neobrufen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulceration, severe heart failure, or those who are in the third trimester of pregnancy. Patients with significant renal or hepatic impairment should also consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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