Product image of Neocardon (Atenolol) supplied by GNH India

Neocardon

Active Ingredient:
Atenolol
Origin:
EU

Neocardon (Atenolol)

Atenolol, the active ingredient in Neocardon, is a beta blocker presented as an oral tablet for oral use. It is employed to manage high blood pressure, relieve angina, and reduce the risk of cardiovascular events after a heart attack, primarily in adult patients.

GNH India supplies Neocardon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution.

Manufacturer / TM Owner

Innovis Pharma

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Indications & Clinical Uses

Neocardon (atenolol) is indicated for several cardiovascular conditions that involve excessive sympathetic activity.

  • Hypertension: lowers systemic blood pressure by reducing heart rate and cardiac output.
  • Angina pectoris: decreases myocardial oxygen demand, relieving chest pain.
  • Post‑myocardial infarction prophylaxis: reduces the risk of recurrent ischemic events and improves survival.
  • Cardiac arrhythmias: helps control heart rate in certain supraventricular tachyarrhythmias.

How It Works

  • Atenolol selectively blocks β1‑adrenergic receptors in the heart, inhibiting the effects of endogenous catecholamines. This reduces heart rate, myocardial contractility, and cardiac output, leading to decreased blood pressure and myocardial oxygen demand. The selectivity for β1 receptors minimizes effects on β2‑mediated bronchial and vascular smooth‑muscle tone.

Side Effects

Atenolol may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Fatigue or tiredness.
  • Dizziness, especially when standing quickly.
  • Cold extremities such as hands and feet.
  • Bradycardia (slow heart rate).
  • Mild gastrointestinal upset (nausea, abdominal discomfort).

Serious or Rare Side Effects

  • Severe bradycardia or heart block.
  • Bronchospasm in patients with asthma or COPD.
  • Masking of hypoglycemia symptoms in diabetic patients.
  • Depression or mood changes.
  • Allergic reactions including rash, itching, or swelling.

Precautions & Warnings

Before initiating atenolol therapy, several safety considerations should be evaluated.

  • Renal impairment: dose may need adjustment in patients with reduced kidney function.
  • Asthma or COPD: use with caution as β1‑selectivity may not fully prevent bronchospasm.
  • Diabetes: monitor blood glucose because atenolol can mask hypoglycemia symptoms.
  • Elderly: start at low dose and titrate slowly due to increased sensitivity.
  • Pregnancy: safety not established; weigh benefits against potential risks.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Atenolol can interact with other medicines, altering its effectiveness or increasing adverse effects.

Major Interactions (Avoid)

  • Non‑selective beta blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): risk of severe AV block.
  • Clonidine: abrupt withdrawal may cause rebound hypertension.

Moderate Interactions (Monitor Closely)

  • Diuretics: enhanced hypotensive effect, monitor blood pressure.
  • Antidiabetic drugs: atenolol may mask hypoglycemia signs; adjust monitoring.
  • NSAIDs: may reduce antihypertensive efficacy of atenolol.

Frequently Asked Questions

Neocardon contains atenolol, a beta‑blocker prescribed to lower high blood pressure, relieve chest pain from angina, prevent further heart attacks after a myocardial infarction, and help control heart rate in certain cardiac arrhythmias. It is used in adult patients when a selective β1‑adrenergic antagonist is appropriate.

Atenolol works by selectively blocking β1‑adrenergic receptors in the heart. This inhibition reduces the influence of adrenaline and noradrenaline, leading to slower heart rate, decreased contractility, and lower cardiac output, which together lower blood pressure and myocardial oxygen demand.

The dose of Neocardon is individualized by the prescribing clinician based on the patient’s condition, response, and tolerability. The prescriber determines the appropriate strength, frequency, and any necessary adjustments, following current clinical guidelines and patient‑specific factors.

Safety data for atenolol during pregnancy and lactation are limited. It is generally classified as a drug to be used only if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their healthcare provider, as atenolol can be excreted in breast milk.

To order Neocardon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Atenolol is a cardio‑selective (β1‑specific) beta blocker, offering fewer respiratory side effects than non‑selective agents such as propranolol. Compared with newer agents like carvedilol, atenolol has a shorter half‑life and lacks additional α‑blocking activity, making it suitable for patients needing pure β1 antagonism.

Neocardon tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and direct sunlight. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Neocardon is taken orally, usually with or without food, as directed by the prescribing clinician. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include severe bradycardia, heart block, bronchospasm in patients with asthma or COPD, and masking of hypoglycemia symptoms in diabetic individuals. Patients should seek immediate medical attention if they experience fainting, severe shortness of breath, or signs of an allergic reaction.

Atenolol is contraindicated in patients with known hypersensitivity to the drug, those with severe bradycardia, second‑ or third‑degree atrioventricular block, and patients with uncompensated heart failure. Caution is also advised for individuals with severe asthma, chronic obstructive pulmonary disease, or significant renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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