Product image of Neodol 400 Mg Oralna Suspenzija (Ibuprofen) supplied by GNH India

Neodol 400 Mg Oralna Suspenzija

Active Ingredient:
Ibuprofen
Origin:
EU

Neodol 400 Mg Oralna Suspenzija (Ibuprofen)

Ibuprofen, the active ingredient in Neodol 400 Mg Oralna Suspenzija, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a 400 mg oral suspension for oral use. It provides analgesic, antipyretic and anti‑inflammatory effects for the relief of mild to moderate pain, fever and inflammatory conditions in both adults and children when prescribed by a healthcare professional.

GNH India supplies Neodol 400 Mg Oralna Suspenzija as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU market standards.

Manufacturer / TM Owner

Jadran-Galenski Laboratorij D.D.

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Indications & Clinical Uses

Ibuprofen, an NSAID, reduces pain, fever and inflammation by inhibiting cyclooxygenase enzymes.

  • Pain: provides relief from headaches, dental pain and musculoskeletal discomfort.
  • Fever: helps lower elevated body temperature associated with infections or other causes.
  • Inflammatory conditions: reduces swelling and discomfort in disorders such as osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen exerts its effect through reversible inhibition of the cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes the inflammatory response, lowers fever, and alleviates pain signals at peripheral and central sites.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain that may occur shortly after dosing.
  • Headache: mild to moderate head pain, often transient.
  • Dizziness: feeling light‑headed or unsteady, usually resolves without intervention.
  • Rash: mild skin irritation, itching or erythema.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage in the stomach or intestines, presenting as black stools or vomiting blood.
  • Renal impairment: reduced kidney function or acute kidney injury, indicated by decreased urine output or swelling.
  • Severe allergic reaction: anaphylaxis, angioedema or bronchospasm requiring immediate medical attention.

Precautions & Warnings

Precautions should be observed when using ibuprofen to minimize risks.

  • Assess renal function: evaluate kidney health before initiating therapy.
  • Monitor gastrointestinal risk: avoid use in patients with active ulcers or a history of gastrointestinal bleeding.
  • Avoid concomitant anticoagulants: increased bleeding risk when combined with warfarin or similar agents.
  • Use the lowest effective dose: limit exposure to reduce adverse events.
  • Pregnancy and lactation: consult a healthcare provider before use during pregnancy or breastfeeding.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with other medicines, affecting safety or efficacy.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Selective COX‑2 inhibitors (e.g., celecoxib): additive cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., enalapril): may reduce antihypertensive effect.
  • Diuretics (e.g., furosemide): potential for reduced renal perfusion.
  • Lithium: ibuprofen may increase lithium serum levels, requiring monitoring.

Frequently Asked Questions

Neodol 400 Mg Oralna Suspenzija is an ibuprofen‑based oral suspension indicated for the relief of mild to moderate pain, reduction of fever, and mitigation of inflammation associated with conditions such as musculoskeletal aches, dental discomfort, and inflammatory joint disorders. It is suitable for use in both adult and pediatric patients when prescribed by a qualified healthcare professional.

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the conversion of arachidonic acid into prostaglandins. By lowering prostaglandin production, ibuprofen reduces the inflammatory response, diminishes pain signaling, and helps lower elevated body temperature, providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Neodol 400 Mg Oralna Suspenzija is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Healthcare providers calculate the dose to achieve effective symptom control while minimizing risk, and patients should follow the specific instructions given by their prescriber.

Safety of ibuprofen‑containing products during pregnancy or lactation depends on the trimester and individual risk factors. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using Neodol 400 Mg Oralna Suspenzija, as the prescriber can assess benefits versus potential risks for both mother and child.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Neodol 400 Mg Oralna Suspenzija. GNH India supplies hospitals, pharmacies and procurement teams across international markets, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Both ibuprofen (Neodol) and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition, providing analgesic, antipyretic and anti‑inflammatory effects. Ibuprofen generally has a shorter half‑life, requiring more frequent dosing, whereas naproxen offers a longer duration of action. Choice between them depends on clinical considerations, patient tolerance, dosing convenience and physician preference.

Neodol 400 Mg Oralna Suspenzija should be stored at ambient temperature, preferably below 25 °C. Keep the suspension in its original container, protect it from moisture, direct sunlight and extreme temperature fluctuations. Do not freeze the product, and ensure the container is tightly sealed when not in use.

The suspension is intended for oral use. Before each dose, shake the bottle gently to ensure uniform distribution of the active ingredient. Measure the prescribed amount using a calibrated oral syringe or dosing spoon provided with the product, and swallow the measured dose with a glass of water. Follow the prescriber’s dosing schedule precisely.

Serious risks of ibuprofen include gastrointestinal bleeding or ulceration, especially in patients with a history of GI disorders; renal impairment or acute kidney injury, particularly in those with pre‑existing kidney disease; cardiovascular events such as heart attack or stroke in high‑risk individuals; and severe allergic reactions like anaphylaxis. Prompt medical attention is required if any of these occur.

Neodol 400 Mg Oralna Suspenzija should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and in patients who have experienced a recent cardiovascular event unless specifically directed by a physician. Pregnant women in the third trimester and patients on certain anticoagulants should also seek medical advice before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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