Product image of Neoflavon (Diosmin, Hesperidin) supplied by GNH India

Neoflavon

Active Ingredient:
Diosmin, Hesperidin
Origin:
EU

Neoflavon (Diosmin, Hesperidin)

Diosmin, the active ingredient in Neoflavon, is a flavonoid presented as an oral tablet for oral use. It treats chronic venous insufficiency, hemorrhoids and varicose veins in adult patients.
GNH India supplies Neoflavon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Extractumpharma Co.Ltd.

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Indications & Clinical Uses

  • Neoflavon, a flavonoid venotonic, is used in conditions affecting venous circulation.
  • Chronic venous insufficiency: improves venous return and reduces leg swelling.
  • Hemorrhoids: alleviates swelling and discomfort of hemorrhoidal tissue.
  • Varicose veins: reduces vein distension and associated pain.

How It Works

  • Diosmin and hesperidin act as venotonic agents by enhancing venous tone, decreasing capillary permeability, and exerting anti‑inflammatory effects. They promote lymphatic drainage and inhibit prostaglandin synthesis, leading to reduced edema and improved microcirculation in the lower extremities.

Side Effects

Neoflavon is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Nausea or mild vomiting
  • Abdominal pain or cramps
  • Headache
  • Dizziness or light‑headedness
  • Transient skin rash or pruritus

Serious or Rare Side Effects

  • Allergic reactions including anaphylaxis
  • Severe thrombocytopenia or bleeding disorders
  • Hepatic dysfunction or elevated liver enzymes
  • Acute hypotension
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Unexplained fever or systemic inflammatory response

Precautions & Warnings

Before using Neoflavon, consider the following safety measures.

  • Age restriction: use in adults only; safety in children not established.
  • Pregnancy: safety category unknown; avoid unless clearly needed.
  • Breastfeeding: caution advised; consult a healthcare professional.
  • Concomitant anticoagulant or antiplatelet therapy may increase bleeding risk.
  • Known hypersensitivity to flavonoids: discontinue use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Neoflavon may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Antiplatelet agents (e.g., clopidogrel): additive antithrombotic effect.
  • Strong CYP3A4 inhibitors: may raise plasma levels of flavonoids.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): potential for additive gastrointestinal irritation.
  • Diuretics: possible electrolyte disturbances.
  • Corticosteroids: may enhance fluid retention and edema.

Frequently Asked Questions

Neoflavon is indicated for the symptomatic management of chronic venous insufficiency, hemorrhoidal disease, and varicose veins. It helps improve venous tone, reduce swelling, and relieve discomfort associated with these vascular conditions.

Diosmin, together with hesperidin, exerts a venotonic effect by strengthening vein walls, decreasing capillary permeability, and reducing inflammatory mediators. This improves blood flow, limits fluid leakage into tissues, and supports lymphatic drainage.

The dosage of Neoflavon is determined by the prescribing healthcare professional based on the individual’s condition, severity, and response to therapy. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Safety data for Neoflavon in pregnancy and lactation are limited. It is classified as having an unknown pregnancy category, so it should only be used if the potential benefit justifies the potential risk. Breastfeeding mothers should consult their physician before use.

To place an order, submit an enquiry on the Neoflavon product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neoflavon combines two flavonoids—diosmin and hesperidin—offering a synergistic venotonic effect. Compared with single‑ingredient venotonics, the dual formulation may provide broader anti‑inflammatory activity and improved capillary protection, though clinical choice depends on individual patient factors and physician judgment.

Neoflavon should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency.

Neoflavon is taken orally, usually with a glass of water. The tablets should be swallowed whole and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, significant bleeding when combined with anticoagulants, and hepatic dysfunction. Patients should seek immediate medical attention if they experience signs of a serious reaction.

Neoflavon should not be used by individuals with known hypersensitivity to diosmin, hesperidin, or any other flavonoids. It is also contraindicated in children, and caution is advised for patients on anticoagulant therapy or with severe liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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