Product image of Neohepatect (Human Hepatitis B Immunoglobulin) supplied by GNH India

Neohepatect

Active Ingredient:
Human Hepatitis B Immunoglobulin
Origin:
EU

Neohepatect (Human Hepatitis B Immunoglobulin)

Human Hepatitis B Immunoglobulin, the active ingredient in Neohepatect, is an immunoglobulin presented as a sterile solution for intravenous use. It provides passive immunity to individuals at risk of hepatitis B virus infection, such as newborns of hepatitis B‑positive mothers, patients undergoing liver transplantation, or those requiring post‑exposure prophylaxis.

GNH India supplies Neohepatect as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology units and pharmacies worldwide, ensuring quality and regulatory compliance across markets and reliable delivery to patients.

Manufacturer / TM Owner

Biotest Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Neohepatect, a human hepatitis B immunoglobulin, provides passive immunity against hepatitis B virus infection.

  • Prevention of mother‑to‑child transmission: administered to newborns of hepatitis B‑positive mothers to reduce the risk of early infection.
  • Post‑exposure prophylaxis: given to individuals after potential hepatitis B exposure to provide immediate passive antibodies until active immunity develops.
  • Pre‑transplant prophylaxis: used in liver transplant candidates and recipients to prevent hepatitis B infection or reactivation during the peri‑operative period.
  • Immunocompromised patient protection: administered to patients with weakened immune systems who are at heightened risk of hepatitis B infection.

How It Works

  • Human hepatitis B immunoglobulin supplies exogenous anti‑HBsAg antibodies that bind to hepatitis B virus particles, neutralizing their ability to infect hepatocytes. The antibodies also facilitate opsonization and clearance of circulating virus by the reticulo‑endothelial system, providing immediate passive immunity while the host’s own adaptive response develops. This rapid antiviral effect reduces viral load and limits hepatic injury during the critical window before active vaccination can elicit protective immunity.

Side Effects

Human hepatitis B immunoglobulin may be associated with the following adverse reactions.

Common Side Effects

  • Fever: mild to moderate temperature elevation.
  • Headache: transient headache reported.
  • Nausea: occasional nausea or upset stomach.
  • Injection site reactions: redness, swelling, or discomfort at the infusion site.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Thrombosis: rare occurrence of blood clot formation.
  • Renal dysfunction: possible acute kidney injury in susceptible patients.

Precautions & Warnings

When using Neohepatect, consider the following precautions to ensure safe administration.

  • Allergy assessment: verify no known hypersensitivity to human immunoglobulins or blood products.
  • Renal function: monitor kidney function in patients with pre‑existing renal impairment.
  • Pregnancy and lactation: weigh potential benefits against unknown risks; use only if clearly indicated.
  • Concurrent immunoglobulin therapy: avoid overlapping doses to prevent excess volume load.
  • Thrombotic risk: assess for history of clotting disorders before infusion.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Human hepatitis B immunoglobulin can interact with certain medications and vaccines.

Major Interactions (Avoid)

  • Live vaccines: concurrent administration may reduce vaccine efficacy; postpone live vaccines for at least 3 months.
  • Immunosuppressants: high‑dose immunoglobulin may augment immunosuppressive effects, increasing infection risk.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: may enhance anticoagulant effect, monitor coagulation parameters.
  • Blood pressure agents: volume load from infusion can affect blood pressure; observe patients with hypertension.
  • Other immunoglobulins: concurrent use may increase risk of hyperviscosity; monitor serum viscosity.

Frequently Asked Questions

Neohepatect is used to provide passive immunity against hepatitis B virus infection. It is indicated for preventing mother‑to‑child transmission, post‑exposure prophylaxis, and protecting patients undergoing liver transplantation or those with compromised immune systems.

Human hepatitis B immunoglobulin contains anti‑HBsAg antibodies that bind to hepatitis B virus particles, neutralizing their ability to infect liver cells. The antibodies also promote clearance of the virus by the reticulo‑endothelial system, delivering immediate protection while the patient’s own immune response develops.

The dose of Neohepatect is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and the specific indication. Dosing guidelines are provided in the product’s prescribing information and should be followed precisely.

The safety of Neohepatect during pregnancy and lactation has not been fully established. Clinicians should weigh the potential benefits against any unknown risks and use the product only when clearly indicated for the mother or infant.

To order Neohepatect, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Neohepatect provides immediate passive immunity through antibodies, whereas hepatitis B vaccines stimulate the patient’s own immune response over weeks. In situations requiring rapid protection—such as newborns of infected mothers or post‑exposure scenarios—HBIG like Neohepatect is preferred, while vaccination remains essential for long‑term immunity.

Neohepatect must be stored at 2‑8 °C (refrigerated). Keep the product in its original container, protect it from light, and avoid freezing or shaking. Inspect the solution before use and discard any product that appears discolored or contains particles.

Neohepatect is administered by intravenous infusion. The infusion rate and volume are determined by the prescribing clinician, and patients should be monitored for any adverse reactions during and after the administration.

The most serious risks include severe allergic reactions such as anaphylaxis, rare thrombotic events, and potential renal dysfunction, especially in patients with pre‑existing kidney disease. Immediate medical attention is required if any of these reactions occur.

Neohepatect should not be used in individuals with known hypersensitivity to human immunoglobulins or any of the product’s excipients. Caution is also advised for patients with severe renal impairment or a history of thrombotic disorders, and use should be avoided unless clearly justified.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Human Hepatitis B Immunoglobulin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT