Product image of Neoimmun (Ciclosporin) supplied by GNH India

Neoimmun

Active Ingredient:
Ciclosporin
Origin:
EU

Neoimmun (Ciclosporin)

Ciclosporin, the active ingredient in Neoimmun, is a calcineurin inhibitor presented as an oral dosage form for oral use. It suppresses immune activity and is employed in organ transplantation, rheumatoid arthritis and psoriasis management.
GNH India supplies Neoimmun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Teva B.V

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Neoimmun, a calcineurin inhibitor, is used in conditions where immune modulation is required.
  • Organ transplantation: prevents graft rejection by inhibiting T‑cell activation.
  • Rheumatoid arthritis: reduces joint inflammation and disease progression.
  • Psoriasis: controls severe plaque psoriasis by dampening immune‑driven skin cell proliferation.

How It Works

  • Ciclosporin binds to cyclophilin, forming a complex that inhibits calcineurin phosphatase activity. This blockade prevents dephosphorylation of nuclear factor of activated T‑cells (NF‑AT), reducing interleukin‑2 transcription and subsequent T‑cell activation, leading to broad immunosuppression.

Side Effects

Ciclosporin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Hypertension: elevated blood pressure requiring monitoring.
  • Hyperlipidaemia: increased cholesterol and triglycerides.
  • Gingival hyperplasia: overgrowth of gum tissue.
  • Tremor: fine shaking of hands.
  • Hirsutism: excessive hair growth.

Serious or Rare Side Effects

  • Nephrotoxicity: impaired kidney function.
  • Severe infections: opportunistic bacterial, viral or fungal infections.
  • Hepatotoxicity: liver enzyme elevation or injury.
  • Lymphoma: increased risk of certain cancers.
  • Anaphylaxis: rare severe allergic reaction.
  • Seizures: neurological events in predisposed patients.

Precautions & Warnings

Before initiating Neoimmun, clinicians should assess baseline health and monitor ongoing parameters.

  • Renal function: check serum creatinine and glomerular filtration rate regularly.
  • Blood pressure: monitor and manage hypertension throughout therapy.
  • Lipid profile: assess cholesterol and triglycerides periodically.
  • Infection risk: avoid live vaccines and screen for latent infections.
  • Hepatic impairment: adjust dose in patients with liver dysfunction.
  • Store at ambient temperature: keep below 25 °C in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ciclosporin interacts with several drug classes; awareness of interaction severity guides clinical decisions.

Major Interactions (Avoid)

  • Ketoconazole: potent CYP3A4 inhibition markedly raises ciclosporin levels.
  • Erythromycin: macrolide antibiotic that can increase drug exposure.
  • Azole antifungals (e.g., fluconazole): elevate plasma concentrations.
  • Grapefruit juice: inhibits metabolism leading to toxicity.
  • Ritonavir: strong CYP3A4 inhibitor causing dangerous accumulation.

Moderate Interactions (Monitor Closely)

  • Calcium channel blockers (e.g., diltiazem): may increase levels, require dose adjustment.
  • Statins (e.g., simvastatin): risk of myopathy, monitor muscle symptoms.
  • NSAIDs: additive nephrotoxic potential, watch renal function.
  • Diuretics: may enhance hypertension, check blood pressure.
  • Rifampicin: enzyme inducer that can lower ciclosporin concentrations.

Frequently Asked Questions

Neoimmun, containing ciclosporin, is prescribed to prevent organ transplant rejection, manage moderate to severe rheumatoid arthritis, and treat extensive plaque psoriasis by suppressing overactive immune responses.

Ciclosporin binds to cyclophilin, forming a complex that blocks calcineurin activity. This inhibition stops the activation of nuclear factor of activated T‑cells, reducing interleukin‑2 production and consequently dampening T‑cell–mediated immune reactions.

The specific dose of Neoimmun is individualized by the prescribing clinician based on the patient’s condition, weight, renal function and other clinical factors. Dosage regimens are not standardized and must follow the prescriber’s instructions.

Safety data for ciclosporin in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the Neoimmun product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with other calcineurin inhibitors, ciclosporin offers a well‑established efficacy profile but may have a higher incidence of nephrotoxicity. Alternatives such as tacrolimus have similar mechanisms with different side‑effect spectra, so the choice depends on patient‑specific factors and physician judgment.

Neoimmun should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and excessive heat to maintain its stability and potency.

Neoimmun is taken orally, usually as a tablet or capsule, with or without food as directed by the prescriber. The exact administration schedule, including timing and whether it should be taken with meals, is determined by the treating physician.

The most serious risks include nephrotoxicity, severe infections, lymphoma or other malignancies, and hepatotoxicity. Patients should be monitored regularly for kidney and liver function, signs of infection and any unusual symptoms, and report concerns promptly to their healthcare provider.

Neoimmun is contraindicated in patients with known hypersensitivity to ciclosporin or any of its excipients, uncontrolled hypertension, active severe infections, and those receiving live vaccines. It should also be used with caution in individuals with pre‑existing kidney or liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ciclosporin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT