Product image of Neolaque (Amorolfine Hydrochloride) supplied by GNH India

Neolaque

Active Ingredient:
Amorolfine Hydrochloride
Origin:
EU

Neolaque (Amorolfine Hydrochloride)

Amorolfine Hydrochloride, the active ingredient in Neolaque, is an antifungal presented as a topical solution for external use. It is indicated for the treatment of fungal infections of the nails and skin, such as onychomycosis and tinea infections, in adult patients.

GNH India supplies Neolaque as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharmaswiss Česká Republika S.R.O.

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Indications & Clinical Uses

Neolaque is an antifungal agent that targets dermatophyte and yeast infections of the nail and skin. It is employed in the following conditions:

  • Onychomycosis: reduces fungal invasion of the nail plate and promotes healthier nail growth.
  • Tinea pedis: alleviates foot fungal infection, relieving itching and scaling.
  • Tinea corporis: treats body ringworm, clearing lesions and preventing spread.

How It Works

  • Amorolfine inhibits ergosterol synthesis by blocking the fungal enzymes Δ14‑reductase and Δ7‑Δ8‑isomerase. This disruption prevents formation of a functional cell membrane, leading to loss of membrane integrity and ultimately inhibiting fungal growth and replication.

Side Effects

Neolaque may cause local skin reactions when applied.

Common Side Effects

  • Irritation: mild burning or stinging at the application site.
  • Redness: localized erythema.
  • Itching: pruritus around treated area.
  • Dryness: skin may become flaky.
  • Scaling: slight desquamation.
  • Contact dermatitis: mild allergic response.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or difficulty breathing.
  • Extensive contact dermatitis: widespread rash or blistering.
  • Angioedema: rapid swelling of face, lips, or tongue.
  • Systemic hypersensitivity: rare systemic symptoms such as fever.
  • Persistent ulceration: non‑healing skin breakdown at application site.
  • Anaphylaxis: life‑threatening reaction requiring immediate medical attention.

Precautions & Warnings

Before using Neolaque, consider the following safety measures:

  • Application area: apply to clean, dry skin as directed.
  • Duration of therapy: prolonged treatment may be required for nail infections.
  • Avoid contact with eyes: keep product away from ocular surfaces.
  • Concurrent skin conditions: use with caution on compromised or inflamed skin.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Neolaque may interact with other topical agents. Review the following interaction categories:

Major Interactions (Avoid)

  • Concurrent use with other topical antifungals: may increase local irritation.
  • Use with topical corticosteroids: may reduce antifungal efficacy.
  • Combination with systemic antifungal therapy: potential additive toxicity, though rare.

Moderate Interactions (Monitor Closely)

  • Alcohol‑based hand sanitizers: may affect product absorption.
  • Use with skin sensitizers: increased risk of dermatitis.
  • Application under occlusive dressings: may raise local drug concentration.
  • Co‑application with other medicated creams: monitor for overlapping side effects.

Frequently Asked Questions

Neolaque is a topical antifungal medication indicated for the treatment of onychomycosis (fungal nail infection) and various tinea infections of the skin, such as athlete's foot and ringworm. It helps to eradicate the causative fungi and improve the appearance of affected nails and skin.

Amorolfine, the active ingredient in Neolaque, blocks two key enzymes in the fungal ergosterol synthesis pathway—Δ14‑reductase and Δ7‑Δ8‑isomerase. By inhibiting these steps, the drug prevents formation of a functional cell membrane, leading to loss of membrane integrity and suppression of fungal growth.

The dosing regimen for Neolaque is determined by the prescribing healthcare professional. Typically, a thin layer is applied to the affected nail or skin once daily, but the exact frequency, amount, and duration depend on the severity of the infection and the clinician’s assessment.

Safety data for Amorolfine in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing Neolaque to pregnant or nursing individuals. Consultation with a specialist is recommended.

To order Neolaque, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Neolaque (Amorolfine) differs from alternatives such as ciclopirox or terbinafine by targeting two distinct steps in ergosterol synthesis, which can result in a broader antifungal spectrum. Clinical experience suggests comparable efficacy for nail infections, while the formulation may offer better tolerability for some patients.

Neolaque should be stored at room temperature, below 25 °C, in its original container. Protect the product from moisture, direct sunlight, and extreme temperatures. Keep the cap tightly closed when not in use to maintain stability.

Neolaque is applied topically to clean, dry skin or nail surfaces. A thin film is spread over the affected area, usually once daily, and allowed to dry. For nail infections, the medication may be applied to the nail plate and surrounding skin as directed by a clinician.

Serious adverse reactions, though rare, include severe allergic responses such as anaphylaxis, extensive contact dermatitis, angioedema, and persistent ulceration at the application site. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, or widespread rash.

Neolaque should be avoided in individuals with known hypersensitivity to Amorolfine or any component of the formulation. Caution is also advised for patients with extensive skin damage, open wounds, or those using conflicting topical medications without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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