Product image of Neovletta 28 (Ethinylestradiol, Levonorgestrel | Lactose Monohydrate) supplied by GNH India

Neovletta 28

Active Ingredient:
Ethinylestradiol, Levonorgestrel | Lactose Monohydrate
Origin:
EU

Neovletta 28 (Ethinylestradiol, Levonorgestrel | Lactose Monohydrate)

Ethinylestradiol, the active ingredient in Neovletta 28, is a combined oral contraceptive presented as an oral tablet for oral use. It works together with levonorgestrel, a progestogenic component that enhances contraceptive efficacy, to prevent pregnancy in women of reproductive age.

GNH India supplies Neovletta 28 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality compliance with EU standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Bayer Ab

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Indications & Clinical Uses

Neovletta 28 is a combined oral contraceptive indicated for hormonal contraception and related menstrual conditions.

  • Contraception: prevention of pregnancy in women of childbearing potential.
  • Menstrual cycle regulation: helps achieve regular menstrual bleeding patterns.
  • Acne treatment: reduces androgen‑dependent skin lesions in women.

How It Works

  • Ethinylestradiol and levonorgestrel act together to suppress the hypothalamic‑pituitary‑gonadal axis, inhibiting the mid‑cycle surge of luteinising hormone and preventing ovulation. The estrogen component stabilises the endometrium, while the progestogen thickens cervical mucus and induces endometrial changes that reduce sperm penetration and implantation.

Side Effects

Neovletta 28 may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like.
  • Breast tenderness: swelling or discomfort.
  • Spotting or breakthrough bleeding: irregular bleeding between periods.
  • Weight gain: modest fluid retention.
  • Mood changes: irritability or mild depression.

Serious or Rare Side Effects

  • Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism.
  • Stroke or transient ischemic attack.
  • Myocardial infarction: heart attack in susceptible individuals.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Hepatic adenoma: benign liver tumor.
  • Hyperbilirubinemia: jaundice due to liver dysfunction.

Precautions & Warnings

Before prescribing Neovletta 28, clinicians should assess individual risk factors and contraindications.

  • Pregnancy contraindication: the product must not be used during pregnancy.
  • Smoking restriction: avoid use in women over 35 who smoke.
  • Thromboembolic history: contraindicated in patients with prior venous or arterial clotting events.
  • Hypertension: caution in uncontrolled high blood pressure.
  • Liver disease: avoid in severe hepatic impairment.
  • Migraine with aura: use only after careful evaluation.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Neovletta 28 can interact with several medicines that alter hormone metabolism or increase clotting risk.

Major Interactions (Avoid)

  • Rifampicin, carbamazepine, phenytoin: enzyme inducers that reduce contraceptive effectiveness.
  • St. John’s wort: herbal inducer that may lower plasma hormone levels.
  • Certain antifungals (ketoconazole, itraconazole): may increase hormone concentrations and risk of side effects.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): may affect bleeding patterns.
  • Antihypertensives (beta‑blockers, ACE inhibitors): monitor blood pressure control.
  • Diuretics: may increase risk of electrolyte imbalance.
  • Warfarin or other anticoagulants: observe for altered coagulation parameters.

Frequently Asked Questions

Neovletta 28 is a combined oral contraceptive indicated primarily for the prevention of pregnancy in women of reproductive age. It is also prescribed to help regulate menstrual cycles and may be used to treat mild to moderate acne that is influenced by hormonal fluctuations.

Ethinylestradiol, the estrogen component of Neovletta 28, suppresses the hypothalamic‑pituitary‑gonadal axis, reducing the surge of luteinising hormone that triggers ovulation. It also stabilises the endometrial lining, contributing to a less favorable environment for implantation while working synergistically with levonorgestrel.

The dosing regimen for Neovletta 28 is determined by the prescribing clinician. Typically, the product is taken once daily for 21 consecutive days followed by a 7‑day hormone‑free interval, but the exact schedule and any adjustments must be individualized by a qualified healthcare professional.

Neovletta 28 is contraindicated during pregnancy (Category X) and should be discontinued if pregnancy is confirmed. While limited data exist for breastfeeding, most guidelines advise caution; the benefits and risks should be evaluated by a healthcare provider before use in lactating women.

To order Neovletta 28, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neovletta 28 contains the standard dose combination of ethinylestradiol and levonorgestrel, a widely used progestogen. Compared with newer formulations that may use different progestins or lower estrogen doses, Neovletta 28 offers a well‑characterised efficacy and safety profile, making it a familiar choice for clinicians accustomed to traditional COC regimens.

Store Neovletta 28 at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack, protect them from moisture and direct sunlight, and ensure they are out of reach of children. Do not use tablets that appear discoloured or damaged.

Neovletta 28 is taken orally with water, preferably at the same time each day. A typical cycle consists of 21 active tablets followed by a 7‑day hormone‑free interval during which withdrawal bleeding occurs. Patients should not skip tablets and should follow the prescriber’s instructions for missed doses.

The most serious risks include venous thromboembolism, arterial clotting events such as stroke or myocardial infarction, and severe allergic reactions. Women with a history of clotting disorders, uncontrolled hypertension, smoking over age 35, or certain liver diseases should be closely monitored or avoid use altogether.

Neovletta 28 should not be used by women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or who are smokers over the age of 35. It is also contraindicated in patients with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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