Product image of Nephrotect (Acetylcysteine, Glycine, L-Lysine Acetate, L-Tryptophan, Glycyl-Tyrosine, L-Arginine, L-Histidine, L) supplied by GNH India

Nephrotect

Active Ingredient:
Acetylcysteine, Glycine, L-Lysine Acetate, L-Tryptophan, Glycyl-Tyrosine, L-Arginine, L-Histidine, L
Origin:
EU

Nephrotect (Acetylcysteine, Glycine, L-Lysine Acetate, L-Tryptophan, Glycyl-Tyrosine, L-Arginine, L-Histidine, L)

Acetylcysteine, the active ingredient in Nephroprotect, is a compound presented as an injectable solution for intravenous use. It is combined with glycine, L‑lysine acetate, L‑tryptophan, glycyl‑tyrosine, L‑arginine and L‑histidine and is intended to support renal function and oxidative balance in clinical settings. GNH India supplies Nephroprotect as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nephroprotect contains a blend of amino acids and acetylcysteine; currently it is not associated with specific approved therapeutic indications.

How It Works

  • The formulation provides acetylcysteine, a precursor of glutathione, which helps replenish intracellular antioxidant capacity, while the accompanying amino acids serve as substrates for protein synthesis and metabolic pathways that support renal cellular health and mitigate oxidative stress during intravenous administration.

Side Effects

Nephroprotect may be associated with adverse reactions typical of intravenous amino‑acid and acetylcysteine preparations.

Common Side Effects

  • Nausea or vomiting: mild gastrointestinal discomfort after infusion.
  • Flushing or warmth: transient sensation at the infusion site.
  • Mild hypotension: temporary drop in blood pressure during administration.
  • Rash or pruritus: skin irritation or itching.
  • Headache: occasional mild headache post‑infusion.

Serious or Rare Side Effects

  • Anaphylactoid reaction: sudden respiratory distress, wheezing or bronchospasm.
  • Severe hypotension: marked drop in blood pressure requiring intervention.
  • Angio‑edema: swelling of face, lips or throat.
  • Hepatic enzyme elevation: significant increase in liver function tests.
  • Hemolysis: rare destruction of red blood cells.
  • Acute renal dysfunction: unexpected worsening of kidney parameters.

Precautions & Warnings

Nephroprotect should be administered under medical supervision with attention to patient history and infusion parameters.

  • Allergy assessment: verify no known hypersensitivity to acetylcysteine or any amino‑acid component.
  • Cardiovascular monitoring: observe blood pressure and heart rate during infusion.
  • Respiratory status: watch for signs of bronchospasm, especially in asthmatic patients.
  • Renal function: evaluate baseline creatinine and adjust infusion if renal impairment is present.
  • Drug compatibility: ensure compatibility with other IV solutions before mixing.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Nephroprotect may interact with certain medications; monitoring is advised.

Major Interactions (Avoid)

  • Nitroglycerin: concurrent use can cause severe hypotension.
  • Warfarin or other anticoagulants: may enhance anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: potential additive effect on blood pressure.
  • Diuretics: may alter electrolyte balance when combined.
  • Other antioxidant agents: possible redundancy or altered pharmacodynamics.

Frequently Asked Questions

Nephroprotect is an intravenous formulation that combines acetylcysteine with several amino acids. It is intended to support renal function and oxidative balance in patients undergoing medical procedures or experiencing renal stress, although specific approved indications may vary by region.

Acetylcysteine serves as a precursor to glutathione, a key intracellular antioxidant. By replenishing glutathione stores, it helps reduce oxidative damage in kidney cells, while the accompanying amino acids provide substrates for protein synthesis and metabolic pathways that further support renal health.

The dosage of Nephroprotect is determined by the prescribing clinician based on the patient’s clinical condition, weight, renal function and the intended therapeutic goal. Healthcare professionals set the appropriate infusion rate and total volume.

Safety data for Nephroprotect in pregnancy or lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Nephroprotect, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Nephroprotect combines acetylcysteine with a broad spectrum of amino acids, offering both antioxidant and metabolic support. Compared with single‑ingredient agents such as plain acetylcysteine, the multi‑component blend may provide additional substrates for renal cell repair, though comparative clinical data are limited.

Nephroprotect should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and extreme temperature fluctuations to maintain stability.

Nephroprotect is given by intravenous infusion. The solution is added to a compatible IV bag or syringe and administered over a period defined by the prescriber, typically under continuous monitoring of vital signs.

Serious risks include anaphylactoid reactions, severe hypotension, angio‑edema, and acute renal dysfunction. Immediate medical attention is required if any signs of severe allergic response, sudden blood pressure drop, or worsening kidney function occur.

Nephroprotect should be avoided in patients with known hypersensitivity to acetylcysteine or any of its amino‑acid components, and in individuals who have experienced severe anaphylactoid reactions to similar intravenous formulations. Clinicians should also exercise caution in patients with unstable cardiovascular status.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.