Product image of Nephrotrans (Sodium Hydrogen Carbonate) supplied by GNH India

Nephrotrans

Active Ingredient:
Sodium Hydrogen Carbonate
Origin:
EU

Nephrotrans (Sodium Hydrogen Carbonate)

Sodium hydrogen carbonate, the active ingredient in Nephrotrans, is an antacid presented as an oral formulation for oral use and is marketed across the European Union. It neutralizes excess gastric acid and helps correct metabolic acidosis, making it useful for patients with acid indigestion, metabolic acidosis, or renal tubular acidosis.

GNH India supplies Nephrotrans as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Medice Arzneimittel Pütter Gmbh & Co. Kg

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nephrotrans, an antacid, is employed to manage conditions where excess acid is present in the gastrointestinal tract or systemic circulation.

  • Acid indigestion: provides rapid relief of heartburn and dyspeptic discomfort by neutralizing gastric acid.
  • Metabolic acidosis: supplies bicarbonate ions that raise systemic pH, assisting correction of acid‑base imbalance.
  • Renal tubular acidosis: helps restore urinary and plasma bicarbonate levels, supporting renal acid excretion.

How It Works

  • After oral administration, sodium hydrogen carbonate dissociates into sodium and bicarbonate ions. The bicarbonate reacts with hydrogen ions in gastric secretions, forming carbonic acid that quickly decomposes to water and carbon dioxide, thereby raising gastric pH. In the systemic circulation, the added bicarbonate increases plasma buffering capacity, contributing to correction of metabolic acidosis and improving renal acid excretion.

Side Effects

Sodium hydrogen carbonate is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Nausea: mild stomach upset.
  • Belching: increased gas from carbon dioxide.
  • Abdominal discomfort: transient bloating.
  • Diarrhea: loose stools at higher doses.

Serious or Rare Side Effects

  • Metabolic alkalosis: excessive blood pH elevation.
  • Severe hypernatremia: high sodium causing neurological signs.
  • Anaphylaxis: rare severe allergic reaction.

Precautions & Warnings

When using Nephrotrans, certain precautions should be observed to minimize risks and ensure safe therapy.

  • Assess renal function: monitor serum creatinine and electrolyte levels before and during treatment.
  • Evaluate cardiac status: avoid in patients with congestive heart failure or fluid overload risk.
  • Review concomitant acid‑suppressing agents: adjust dosing if used together with proton‑pump inhibitors or H2 blockers.
  • Use caution in pregnancy: limited data; benefits must outweigh potential risks.
  • Monitor serum electrolytes: watch for hypernatremia, hypokalemia, and metabolic alkalosis.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Sodium hydrogen carbonate can alter the absorption or activity of several medicines; awareness of key interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Digoxin: increased risk of toxicity due to altered potassium balance.
  • Lithium: reduced renal clearance may lead to lithium toxicity.
  • Tetracycline antibiotics: decreased absorption and reduced efficacy.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: potential for metabolic alkalosis.
  • NSAIDs: may impair renal excretion of bicarbonate.
  • Loop diuretics: increased risk of hypokalemia.

Frequently Asked Questions

Nephrotrans is indicated for relief of acid indigestion, correction of metabolic acidosis, and management of renal tubular acidosis. In each case the product supplies bicarbonate ions that neutralize excess acid, helping to restore a normal pH balance in the stomach or systemic circulation.

Sodium hydrogen carbonate dissociates after oral intake, releasing bicarbonate ions. These ions combine with hydrogen ions in gastric juice to form carbonic acid, which quickly breaks down into water and carbon dioxide, raising gastric pH. Systemically, the added bicarbonate increases the blood’s buffering capacity, aiding correction of metabolic acidosis.

The appropriate dose of Nephrotrans is set by the prescribing healthcare professional based on the individual’s condition, severity of acid excess, renal function, and other concurrent medications. No fixed dosing regimen is provided here; patients should follow the prescriber’s instructions.

Safety data for sodium hydrogen carbonate in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers should evaluate each case and discuss potential risks with the patient.

To order Nephrotrans, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Nephrotrans (sodium hydrogen carbonate) provides rapid systemic alkalinization, whereas calcium‑based antacids mainly act locally in the stomach. Compared with potassium citrate, sodium bicarbonate supplies sodium rather than potassium, which may be preferable in patients who need to avoid potassium loading but requires monitoring of sodium balance.

Nephrotrans should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and excessive heat to maintain product stability.

Nephrotrans is taken orally. It may be swallowed whole with water or, if formulated as a powder, dissolved in a suitable liquid before ingestion. The exact method depends on the dosage form supplied by the manufacturer.

The most serious risks include metabolic alkalosis, severe hypernatremia, and rare anaphylactic reactions. These conditions can lead to neurological symptoms, cardiac arrhythmias, or life‑threatening airway compromise and require immediate medical attention.

Nephrotrans should be avoided in patients with severe renal impairment, uncontrolled congestive heart failure, known hypersensitivity to sodium bicarbonate, or existing hypernatremia. Individuals on medications that significantly alter electrolyte balance should also consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Hydrogen Carbonate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT