Product image of Nettacin (Netilmicin) supplied by GNH India

Nettacin

Active Ingredient:
Netilmicin
Origin:
EU

Nettacin (Netilmicin)

Netilmicin, the active ingredient in Nettacin, is an aminoglycoside antibiotic presented as an ophthalmic solution for ocular use. It is employed to treat bacterial conjunctivitis and other bacterial eye infections in patients requiring topical antimicrobial therapy. The drug works by inhibiting bacterial protein synthesis, leading to rapid bacterial cell death and resolution of infection.

GNH India supplies Nettacin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, eye‑care centres and clinics worldwide, with consistent quality and regulatory compliance.

Manufacturer / TM Owner

Sifi S.P.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Netilmicin is used to treat bacterial ocular infections by targeting susceptible Gram‑positive and Gram‑negative organisms.

  • Bacterial conjunctivitis: reduces bacterial load and alleviates redness, discharge and irritation.
  • Bacterial keratitis: eradicates causative pathogens to promote corneal healing.
  • Post‑operative ocular infection: prevents or treats infection following eye surgery.

How It Works

  • Netilmicin binds to the bacterial 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis. This disruption leads to rapid bacterial cell death, particularly against Gram‑negative and some Gram‑positive ocular pathogens, facilitating clearance of infection in the eye.

Side Effects

Adverse ocular reactions may occur with Nettacin use.

Common Side Effects

  • Eye irritation: mild burning or stinging upon instillation.
  • Redness: transient conjunctival hyperemia.
  • Tearing: increased lacrimation.
  • Foreign body sensation: feeling of grit in the eye.
  • Blurred vision: temporary visual disturbance after dosing.
  • Eyelid swelling: mild peri‑ocular edema.

Serious or Rare Side Effects

  • Allergic reaction: swelling, rash or severe itching of the eye.
  • Corneal ulceration: progressive loss of corneal tissue.
  • Severe eye pain: intense discomfort indicating possible toxicity.
  • Vision loss: rare but may occur with extensive corneal damage.
  • Systemic nephrotoxicity: renal impairment if significant systemic absorption.
  • Ototoxicity: hearing impairment in rare systemic exposure cases.

Precautions & Warnings

Before prescribing Nettacin, consider the following precautions.

  • Hypersensitivity assessment: verify no known allergy to aminoglycosides or Netilmicin.
  • Indication confirmation: use only for confirmed bacterial eye infections.
  • Contact lens use: advise patients to remove lenses during treatment.
  • Renal monitoring: consider renal function in prolonged therapy due to possible systemic absorption.
  • Concomitant ototoxic drugs: avoid use with other ototoxic agents if systemic exposure is possible.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Nettacin may interact with other medicines; consider the following.

Major Interactions (Avoid)

  • Systemic aminoglycosides: additive nephro‑ and ototoxicity risk.
  • Loop diuretics: increased risk of renal toxicity.
  • Neuromuscular blocking agents: enhanced neuromuscular blockade.

Moderate Interactions (Monitor Closely)

  • Topical ophthalmic steroids: may mask infection signs.
  • Non‑steroidal anti‑inflammatory eye drops: potential for increased ocular irritation.
  • Other ototoxic drugs: monitor for systemic absorption‑related toxicity.

Frequently Asked Questions

Nettacin contains Netilmicin and is indicated for the treatment of bacterial conjunctivitis and other bacterial eye infections. It is applied topically to the eye to eradicate susceptible pathogens and relieve symptoms such as redness, discharge, and irritation.

Netilmicin binds to the bacterial 30S ribosomal subunit, causing misreading of messenger RNA and blocking protein synthesis. This action leads to rapid bacterial cell death, especially against Gram‑negative organisms commonly responsible for ocular infections.

The dosing regimen for Nettacin is determined by the prescribing clinician based on the severity of the infection, patient age, and response to therapy. Healthcare professionals select the appropriate number of drops and frequency according to clinical guidelines.

Safety data for Netilmicin in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Nettacin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nettacin (Netilmicin) belongs to the aminoglycoside class, offering broad‑spectrum activity against many Gram‑negative ocular pathogens. Compared with fluoroquinolone eye drops, it may have a lower risk of developing resistance but shares similar topical efficacy; choice depends on local susceptibility patterns and patient tolerance.

Store Nettacin at room temperature, preferably below 25 °C, in its original container. Protect the product from direct light, moisture and extreme temperatures. Keep the vial tightly closed when not in use and discard any solution that appears discolored or contaminated.

Nettacin is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow distribution, and contact lenses should be removed during treatment.

Serious adverse events include allergic reactions such as severe eye swelling or rash, corneal ulceration, significant eye pain, and rare systemic toxicity like nephrotoxicity or ototoxicity if systemic absorption occurs. Immediate medical attention is required if any of these symptoms develop.

Patients with a known hypersensitivity to Netilmicin, other aminoglycosides, or any component of the formulation should avoid Nettacin. It is also contraindicated in individuals with pre‑existing severe renal impairment when systemic exposure is possible, and in those using concurrent ototoxic medications without close monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.