Product image of Neuramin (Thiamine) supplied by GNH India

Neuramin

Active Ingredient:
Thiamine
Origin:
EU

Neuramin (Thiamine)

Thiamine, the active ingredient in Neuramin, is a vitamin (B1) presented as an injectable solution for intramuscular and intravenous use. It addresses thiamine deficiency conditions such as beriberi and Wernicke’s encephalopathy in patients at risk of inadequate vitamin B1 levels.

GNH India supplies Neuramin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orion Corporation

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Neuramin is used to treat disorders related to thiamine deficiency and its metabolic consequences.

  • Thiamine deficiency (beriberi): restores normal carbohydrate metabolism and alleviates cardiovascular and neurological symptoms.
  • Wernicke's encephalopathy: prevents progression of acute neurological damage in at‑risk individuals.
  • At‑risk populations (e.g., chronic alcoholism, malnutrition): maintains adequate thiamine levels to support energy production and nerve function.

How It Works

  • Thiamine acts as an essential cofactor for several enzymes in carbohydrate metabolism, including pyruvate dehydrogenase, α‑ketoglutarate dehydrogenase, and transketolase. By facilitating these enzymatic reactions, it supports aerobic energy production, neuronal function, and the synthesis of nucleic acids, thereby correcting metabolic deficits caused by thiamine shortage.

Side Effects

Thiamine administered intravenously or intramuscularly may be associated with a range of adverse reactions.

Common Side Effects

  • Injection site pain or erythema
  • Nausea or vomiting
  • Headache
  • Dizziness or light‑headedness
  • Transient flushing
  • Mild fever

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypersensitivity (rash, angioedema)
  • Hypotension or cardiovascular collapse
  • Cardiac arrhythmias
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Seizures

Precautions & Warnings

Thiamine should be used with consideration of patient‑specific factors and proper handling.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: assess risk‑benefit ratio with a clinician.
  • Renal impairment: monitor for accumulation and adjust therapy if needed.
  • Hepatic impairment: use with caution and observe liver function.
  • Concomitant medications: review potential interactions before initiating therapy.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Thiamine may interact with certain drugs, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • High‑dose phenobarbital or other enzyme‑inducing anti‑epileptics: may increase thiamine metabolism and reduce effectiveness.
  • Known hypersensitivity to thiamine or formulation excipients: avoid administration.

Moderate Interactions (Monitor Closely)

  • Chronic alcohol consumption: can increase thiamine requirement and diminish response.
  • Loop diuretics (e.g., furosemide): may enhance urinary thiamine loss.
  • Metformin: potential alteration of thiamine absorption.
  • Warfarin: monitor INR as vitamin B1 may affect coagulation parameters.
  • Other B‑vitamin supplements: assess for synergistic effects and adjust dosing if necessary.

Frequently Asked Questions

Neuramin is a pharmaceutical preparation of thiamine (vitamin B1) used to treat and prevent thiamine deficiency conditions such as beriberi, Wernicke’s encephalopathy, and deficiency in patients with chronic alcoholism, malnutrition, or other risk factors that impair vitamin B1 status.

Thiamine serves as a cofactor for key enzymes in carbohydrate metabolism, including pyruvate dehydrogenase, α‑ketoglutarate dehydrogenase, and transketolase. By supporting these enzymatic steps, it enables efficient energy production, nerve function, and synthesis of nucleic acids, thereby correcting metabolic disturbances caused by deficiency.

The appropriate dose of Neuramin is determined by the prescribing healthcare professional based on the patient’s clinical condition, severity of deficiency, route of administration, and individual health factors. Dosage regimens are not standardized and should follow the prescriber’s instructions.

Safety data for thiamine in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing Neuramin to pregnant or breastfeeding individuals. Consultation with a medical professional is essential.

To place an order, submit an enquiry on the Neuramin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Neuramin is a sterile injectable form of thiamine, offering rapid systemic availability compared with oral tablets or capsules, which may be limited by gastrointestinal absorption. For acute deficiency or neurological emergencies, injectable thiamine provides faster correction, while oral formulations are suitable for maintenance therapy.

Neuramin should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability and sterility.

Neuramin is administered by a qualified healthcare professional via intramuscular or intravenous injection. The route, injection site, and infusion rate are selected according to the patient’s condition and the prescriber’s orders.

Serious adverse reactions, although rare, include anaphylaxis, severe hypersensitivity (e.g., rash, angioedema), hypotension, cardiac arrhythmias, and neurological events such as seizures. Immediate medical attention is required if any of these symptoms occur after administration.

Neuramin is contraindicated in individuals with a known hypersensitivity to thiamine or any component of the injectable formulation. Patients with uncontrolled severe cardiac disease should use it only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.