Product image of Neurapas (Dry Extract Of St. John's Wort (4,6-6,5:1), Extraction Solvent: Ethanol 38% M/M, Dry Extract Of Vale) supplied by GNH India

Neurapas

Active Ingredient:
Dry Extract Of St. John's Wort (4,6-6,5:1), Extraction Solvent: Ethanol 38% M/M, Dry Extract Of Vale
Origin:
EU

Neurapas (Dry Extract Of St. John's Wort (4,6-6,5:1), Extraction Solvent: Ethanol 38% M/M, Dry Extract Of Vale)

St. John's Wort dry extract, the active ingredient in Neurapas, is a herbal supplement presented as an oral dry‑extract preparation for oral use. It is traditionally used to support mood balance in adults.

GNH India supplies Neurapas as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pascoe Pharmazeutische Präparate Gmbh

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Indications & Clinical Uses

Neurapas, a St. John's Wort dry extract, is used within the mood‑regulation and mild depressive symptom pathway.

  • Mild to moderate depressive episodes: may help improve mood and emotional well‑being.
  • Seasonal affective disorder: may alleviate low mood during winter months.
  • Occasional anxiety or stress: may support emotional balance.

How It Works

  • St. John's Wort contains hypericin, hyperforin and related flavonoids that modulate neurotransmitter activity. The extract is thought to inhibit the reuptake of serotonin, dopamine and norepinephrine, and to influence intracellular signaling pathways, thereby contributing to mood‑stabilising effects.

Side Effects

St. John's Wort dry extract may be associated with several adverse reactions.

Common Side Effects

  • Gastrointestinal discomfort: nausea, stomach cramps.
  • Dry mouth: reduced salivation.
  • Dizziness or light‑headedness.
  • Fatigue or mild drowsiness.
  • Photosensitivity: increased skin sensitivity to sunlight.
  • Headache: mild to moderate.

Serious or Rare Side Effects

  • Serotonin syndrome: potentially life‑threatening when combined with serotonergic drugs.
  • Severe allergic reactions: rash, swelling, anaphylaxis.
  • Significant photosensitivity: severe sunburns.
  • Liver enzyme elevation: possible hepatic stress.
  • Induction of mania or hypomania in susceptible individuals.

Precautions & Warnings

When considering Neurapas, several safety measures are recommended.

  • Consult healthcare professional before use: especially if taking antidepressants or other serotonergic agents.
  • Avoid prolonged sun exposure: risk of photosensitivity reactions.
  • Do not use with MAO inhibitors: increased risk of serotonin syndrome.
  • Monitor for mood changes: possible induction of mania or hypomania.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

St. John's Wort dry extract can affect the activity of several medicines.

Major Interactions (Avoid)

  • Selective serotonin reuptake inhibitors (SSRIs): risk of serotonin syndrome.
  • Monoamine oxidase inhibitors (MAOIs): heightened serotonergic activity.
  • Other serotonergic agents (tramadol, linezolid): increased serotonin toxicity.
  • Oral anticoagulants (warfarin): reduced anticoagulant effect.
  • Hormonal contraceptives: decreased efficacy.

Moderate Interactions (Monitor Closely)

  • Cytochrome P450 substrates (e.g., cyclosporine, tacrolimus): possible reduced plasma levels.
  • Antiretroviral drugs (e.g., indinavir): altered drug concentrations.
  • Antihistamines (e.g., diphenhydramine): variable response.
  • Digoxin: potential decrease in serum concentration.
  • Certain antiepileptic drugs (e.g., carbamazepine): enhanced metabolism.

Frequently Asked Questions

Neurapas contains a dry extract of St. John's Wort and is used as an over‑the‑counter herbal supplement to support mood balance, help manage mild to moderate depressive symptoms, and alleviate occasional anxiety or seasonal affective changes in adults.

The active constituents, such as hypericin and hyperforin, influence neurotransmitter pathways by inhibiting the reuptake of serotonin, dopamine and norepinephrine, and by modulating intracellular signaling, which together may contribute to improved mood and emotional stability.

The appropriate dose of Neurapas is determined by a qualified healthcare professional based on individual needs, product formulation and local regulatory guidance. Patients should follow the prescriber’s instructions and the label directions.

Safety data for St. John's Wort during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using Neurapas to weigh potential risks and benefits.

To place an order, submit an enquiry on the Neurapas product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neurapas provides a standardized St. John's Wort dry extract, which differs from generic herbal blends by offering a consistent concentration of active constituents. Compared with other herbal mood‑support products, it has a well‑documented profile of serotonergic activity, but it also carries a higher potential for drug interactions.

Neurapas should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and excessive heat to maintain product stability.

Neurapas is taken orally, usually with water. The specific administration instructions, such as timing relative to meals, should follow the prescriber’s guidance and the product label.

The most serious risks include the potential for serotonin syndrome when combined with other serotonergic drugs, severe photosensitivity reactions, and possible induction of mania or hypomania in individuals with bipolar disorder. Prompt medical attention is required if these events occur.

Neurapas should be avoided by individuals taking monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, other serotonergic medications, or those with known hypersensitivity to St. John's Wort. People with bipolar disorder, severe liver disease or uncontrolled thyroid conditions should also consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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