Product image of Neurisol (Gabapentin) supplied by GNH India

Neurisol

Active Ingredient:
Gabapentin
Origin:
EU

Neurisol (Gabapentin)

Gabapentin, the active ingredient in Neurisol, is an anticonvulsant (gabapentinoid) presented as an oral tablet for oral use. It is used to manage neuropathic pain, post‑herpetic neuralgia, partial seizures and restless legs syndrome in adult patients.
GNH India supplies Neurisol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Oresund Pharma Aps

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Indications & Clinical Uses

Gabapentin acts on the nervous system to alleviate pain and control seizure activity.

  • Neuropathic pain: reduces pain intensity associated with peripheral nerve damage.
  • Post‑herpetic neuralgia: alleviates chronic pain following shingles infection.
  • Partial seizures: provides adjunctive seizure control in epilepsy.
  • Restless legs syndrome: diminishes uncomfortable sensations and urges to move the legs.

How It Works

  • Gabapentin binds selectively to the α2δ subunit of voltage‑gated calcium channels in neuronal membranes, decreasing calcium influx and consequently reducing the release of excitatory neurotransmitters such as glutamate, norepinephrine and substance P. This modulation dampens neuronal hyperexcitability that underlies pain signaling and seizure propagation.

Side Effects

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Somnolence: increased sleepiness or fatigue.
  • Peripheral edema: swelling of the lower limbs.
  • Nausea: mild stomach upset.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Stevens‑Johnson syndrome: rare skin blistering condition.
  • Suicidal thoughts: emergence of depressive or suicidal ideation.

Precautions & Warnings

Gabapentin requires careful monitoring in several clinical situations.

  • Renal function: dose adjustment may be needed in impaired kidney function.
  • CNS depression: avoid concomitant use with alcohol or other sedatives.
  • Pregnancy: safety data are limited; use only if clearly needed.
  • Elderly patients: monitor for dizziness and falls.
  • Concomitant antacids: may reduce absorption; separate dosing times.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Gabapentin can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce gabapentin absorption.
  • CNS depressants (e.g., opioids, benzodiazepines): increase risk of sedation and respiratory depression.
  • Opioid analgesics: may potentiate respiratory depression.

Moderate Interactions (Monitor Closely)

  • NSAIDs: combined use may affect renal function.
  • ACE inhibitors: monitor kidney function when used together.
  • Alcohol: may enhance central nervous system effects.

Frequently Asked Questions

Neurisol, containing gabapentin, is prescribed for neuropathic pain, post‑herpetic neuralgia, as an adjunctive treatment for partial seizures in epilepsy, and for managing restless legs syndrome in adults.

Gabapentin binds to the α2δ subunit of voltage‑gated calcium channels, decreasing calcium entry into neurons and reducing the release of excitatory neurotransmitters, which helps to calm overactive nerve signals that cause pain or seizures.

The appropriate dose of Neurisol is determined individually by a prescriber based on the patient’s condition, response, and renal function. Dosage regimens are not standardized and should follow the prescribing clinician’s instructions.

Safety data for gabapentin in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with other anticonvulsants such as pregabalin, gabapentin (Neurisol) has a similar mechanism but may differ in dosing frequency and individual tolerability. Choice of therapy depends on clinical response, side‑effect profile, cost and patient-specific factors.

Neurisol should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children.

Neurisol is taken orally, usually with or without food, as directed by a healthcare professional. Tablets should be swallowed whole with water and not crushed or chewed unless specifically instructed.

Serious risks include severe allergic reactions, Stevens‑Johnson syndrome, suicidal thoughts or behaviors, and respiratory depression, especially when combined with other central nervous system depressants. Patients should seek immediate medical attention if any of these occur.

Neurisol is contraindicated in patients with known hypersensitivity to gabapentin or any of its excipients. Caution is advised for individuals with severe renal impairment, uncontrolled depression, or those taking multiple CNS depressants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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