Product image of Neurisol (Gabapentin) supplied by GNH India

Neurisol

Active Ingredient:
Gabapentin
Origin:
EU

Neurisol (Gabapentin)

Gabapentin, the active ingredient in Neurisol, is a gabapentinoid presented as an oral formulation for oral use. It is prescribed for the management of epilepsy and neuropathic pain in adult patients.\n\nGNH India supplies Neurisol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Oresund Pharma Aps

1
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Indications & Clinical Uses

  • Gabapentin is used to treat disorders involving abnormal neuronal excitability and chronic pain pathways.\n\nEpilepsy: reduces the frequency of partial seizures and adjunctive seizure control.\nNeuropathic pain: alleviates pain associated with diabetic peripheral neuropathy.\nPostherpetic neuralgia: helps relieve persistent pain following shingles infection.

How It Works

  • Gabapentin binds selectively to the α2δ subunit of voltage‑gated calcium channels in the central nervous system. This binding decreases calcium influx into presynaptic neurons, which in turn reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine and substance P, dampening neuronal hyper‑excitability and pain signaling.

Side Effects

  • Gabapentin may cause a range of adverse reactions, from mild to severe.\n\nCommon Side Effects:\n- Dizziness\n- Somnolence or fatigue\n- Peripheral edema\n- Ataxia or unsteady gait\n- Weight gain\n- Visual disturbances\n\nSerious or Rare Side Effects:\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis\n- Suicidal thoughts or behavior\n- Severe allergic reactions (e.g., anaphylaxis)\n- Respiratory depression, especially with concomitant CNS depressants\n- Blood dyscrasias such as agranulocytosis\n- Hepatic failure or severe liver injury

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.\n\nRenal impairment: adjust dose based on creatinine clearance.\nCNS depression: avoid concurrent use with alcohol or other sedatives.\nPregnancy: use only if potential benefit justifies potential risk to the fetus.\nSuicidality: monitor for mood changes or suicidal ideation.\nConcomitant antacids: separate administration by at least 2 hours to ensure absorption.\nStore at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Gabapentin can interact with several drug classes, requiring attention to dosing and monitoring.\n\nMajor Interactions (Avoid):\n- Opioids: increased risk of respiratory depression and profound sedation.\n- CNS depressants (e.g., benzodiazepines, barbiturates): additive central nervous system depression.\n- Antacids containing aluminum or magnesium: may reduce gabapentin absorption if taken simultaneously.\n\nModerate Interactions (Monitor Closely):\n- NSAIDs: may enhance risk of peripheral edema.\n- Antihypertensives: potential additive hypotensive effect.\n- Carbamazepine or phenytoin: may lower gabapentin plasma concentrations, reducing efficacy.

Frequently Asked Questions

Neurisol contains gabapentin, which is prescribed for the treatment of epilepsy, particularly partial seizures, and for managing neuropathic pain conditions such as diabetic peripheral neuropathy and postherpetic neuralgia. It works as an adjunct therapy to help control seizure activity and to reduce chronic pain signals.

Gabapentin binds to the α2δ subunit of voltage‑gated calcium channels in the central nervous system. This binding limits calcium entry into nerve terminals, decreasing the release of excitatory neurotransmitters like glutamate and substance P, thereby reducing neuronal hyper‑excitability and pain transmission.

The appropriate dose of Neurisol is determined individually by a qualified prescriber based on the patient’s medical condition, age, renal function and response to therapy. Healthcare professionals will establish the dosing regimen and any necessary adjustments.

Safety data for gabapentin in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss risks and alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Neurisol. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with many traditional anticonvulsants, gabapentin has a distinct mechanism targeting calcium channel subunits rather than sodium channels. It is generally well tolerated, has fewer drug‑enzyme interactions, and is often chosen for patients who need adjunct seizure control or neuropathic pain relief, though efficacy varies by individual condition.

Neurisol should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Neurisol is taken orally, usually with or without food, as directed by the prescribing clinician. The tablets (or capsules) should be swallowed whole with a glass of water. Patients should follow the prescriber’s instructions regarding timing and any dose adjustments.

Serious risks include the potential for severe allergic reactions such as Stevens‑Johnson syndrome, respiratory depression when combined with other CNS depressants, suicidal thoughts or behavior, and rare blood disorders. Patients should seek immediate medical attention if they notice rash, difficulty breathing, mood changes or unexplained bruising.

Neurisol is contraindicated in patients with known hypersensitivity to gabapentin or any of its excipients. Caution is advised for individuals with severe renal impairment, uncontrolled depression, or a history of suicidal ideation. Pregnant or breastfeeding women should only use it after thorough risk‑benefit evaluation by their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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