Product image of Neurobixin (Benfotiamine, Pyridoxine Hydrochloride) supplied by GNH India

Neurobixin

Active Ingredient:
Benfotiamine, Pyridoxine Hydrochloride
Origin:
EU

Neurobixin (Benfotiamine, Pyridoxine Hydrochloride)

Benfotiamine and Pyridoxine Hydrochloride, the active ingredients in Neurobixin, are nutritional supplements presented as an oral formulation for dietary support use. They help maintain normal glucose metabolism and nerve health in adults.

GNH India supplies Neurobixin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

G.L. Pharma Gmbh

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Indications & Clinical Uses

Neurobixin combines benfotiamine and pyridoxine to address conditions related to nerve function and vitamin B metabolism.

  • Diabetic peripheral neuropathy: supports nerve function and may reduce oxidative stress associated with high blood glucose.
  • Vitamin B6 deficiency: restores normal pyridoxine levels and assists in amino‑acid metabolism.
  • General metabolic support: contributes to carbohydrate metabolism and overall nutritional balance.

How It Works

  • Benfotiamine, a lipid‑soluble thiamine derivative, is converted to thiamine diphosphate, enhancing transketolase activity and reducing formation of advanced glycation end‑products. Pyridoxine hydrochloride is converted to pyridoxal‑5′‑phosphate, a co‑enzyme essential for amino‑acid transamination, neurotransmitter synthesis, and glycogenolysis, thereby supporting nerve health and metabolic processes.

Side Effects

Neurobixin is generally well tolerated, but some users may experience mild reactions.

Common Side Effects

  • Nausea: occasional stomach upset.
  • Headache: mild, transient.
  • Skin rash: mild erythema or itching.
  • Dizziness: brief light‑headedness.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, breathing difficulty.
  • Anaphylaxis: rapid onset of systemic symptoms.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Peripheral neuropathy worsening: rare exacerbation of existing nerve symptoms.

Precautions & Warnings

Before using Neurobixin, consider the following safety points.

  • Assess renal function: adjust use if kidney impairment is present.
  • Monitor for allergic reactions: discontinue if rash or swelling occurs.
  • Use with caution in pregnancy: safety not fully established.
  • Do not exceed recommended dose: follow prescriber guidance.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Neurobixin may interact with certain medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Alcohol: can exacerbate neuropathy and diminish supplement benefit.
  • High‑dose thiamine preparations: may lead to thiamine excess.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., phenobarbital): may increase pyridoxine metabolism, reducing effectiveness.
  • Isoniazid therapy: can heighten risk of peripheral neuropathy if pyridoxine is not supplemented.
  • Certain chemotherapy agents: may alter vitamin metabolism, requiring monitoring.

Frequently Asked Questions

Neurobixin is an oral nutritional supplement that combines benfotiamine and pyridoxine hydrochloride. It is used to support nerve health, assist in normal glucose metabolism, and address vitamin B6 deficiency, particularly in adults with metabolic or neuropathic concerns.

Benfotiamine is a lipid‑soluble form of thiamine that raises intracellular thiamine diphosphate levels. This enhances the activity of the enzyme transketolase, helping to divert harmful glucose metabolites away from pathways that generate advanced glycation end‑products, thereby protecting nerves and supporting metabolic balance.

The appropriate dose of Neurobixin is determined by the prescribing healthcare professional based on the individual’s condition, age, and overall health. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Neurobixin in pregnancy and lactation are limited. It should be used only if the prescriber judges that the potential benefit outweighs any possible risk to the fetus or infant. Women who are pregnant or breastfeeding should discuss use with their healthcare provider.

To order Neurobixin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neurobixin uniquely combines benfotiamine, a thiamine derivative with strong evidence for reducing advanced glycation end‑products, and pyridoxine, a vitamin B6 source essential for neurotransmitter synthesis. Many other supplements contain only one of these vitamins, so Neurobixin offers a broader metabolic and neuroprotective profile.

Neurobixin should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Neurobixin is taken orally, usually with water. The tablet or capsule should be swallowed whole and not chewed or crushed unless the prescriber advises otherwise. It can be taken with or without food, depending on individual tolerance.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, significant skin eruptions, and possible liver enzyme elevations. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, rash, or unexplained jaundice.

Neurobixin should be avoided by individuals with known hypersensitivity to benfotiamine, pyridoxine, or any excipients in the formulation. It is also not recommended for patients with severe renal impairment unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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