Product image of Neurol Sr (Alprazolam) supplied by GNH India

Neurol Sr

Active Ingredient:
Alprazolam
Origin:
EU

Neurol Sr (Alprazolam)

Alprazolam, the active ingredient in Neurol Sr, is a benzodiazepine presented as an oral tablet for oral use. It treats anxiety disorders, panic disorder and generalized anxiety disorder in adult patients.
GNH India supplies Neurol Sr as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zentiva, K.S.

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Indications & Clinical Uses

Alprazolam acts on the central nervous system to relieve symptoms of anxiety‑related conditions.

  • Anxiety disorders: reduces excessive worry and tension.
  • Panic disorder: alleviates sudden episodes of intense fear.
  • Generalized anxiety disorder: controls chronic, pervasive anxiety.

How It Works

  • Alprazolam binds to a specific site on the GABA‑A receptor complex, acting as a positive allosteric modulator. This enhances the inhibitory effect of the neurotransmitter GABA, increasing chloride ion influx and producing neuronal hyperpolarisation, which results in anxiolytic, sedative and muscle‑relaxant effects.

Side Effects

Alprazolam may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Drowsiness
  • Dizziness
  • Fatigue
  • Impaired coordination

Serious or Rare Side Effects

  • Respiratory depression
  • Dependence or addiction
  • Severe withdrawal symptoms
  • Allergic reactions such as rash or angioedema

Precautions & Warnings

When prescribing alprazolam, clinicians should consider several safety measures.

  • Assess risk of dependence: evaluate patient history before initiating therapy.
  • Avoid abrupt discontinuation: taper dose under medical supervision.
  • Monitor for respiratory depression: especially in patients with pulmonary disease.
  • Caution in elderly: increased sensitivity to sedation and falls.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Alprazolam interacts with several drug classes that may alter its safety or efficacy.

Major Interactions (Avoid)

  • CNS depressants: may cause profound sedation.
  • Opioids: increased risk of respiratory depression.
  • Alcohol: enhances sedative effects.
  • Azole antifungals (e.g., ketoconazole): may raise alprazolam plasma levels.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inhibitors (e.g., erythromycin): may increase plasma concentrations.
  • CYP3A4 inducers (e.g., rifampin): may reduce therapeutic effect.
  • Antidepressants (e.g., SSRIs): may augment sedation.

Frequently Asked Questions

Neurol Sr contains alprazolam, a benzodiazepine prescribed to manage anxiety disorders, panic disorder and generalized anxiety disorder. It helps reduce excessive worry, sudden panic attacks and chronic anxiety symptoms in adult patients.

Alprazolam acts as a positive allosteric modulator at the GABA‑A receptor. By enhancing GABA’s inhibitory action, it increases chloride influx into neurons, leading to reduced neuronal excitability and producing anxiolytic, sedative and muscle‑relaxant effects.

The appropriate dose of Neurol Sr is determined individually by a qualified prescriber based on the patient’s condition, response and clinical factors. No standard regimen is provided here; the prescribing clinician sets the exact dosage.

Safety data for alprazolam in pregnancy and lactation are limited, and the drug is generally avoided unless clearly needed. Women who are pregnant, planning pregnancy or breastfeeding should discuss risks and alternatives with their healthcare provider.

To request Neurol Sr, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neurol Sr (alprazolam) is a short‑acting benzodiazepine with rapid onset, making it effective for acute anxiety and panic attacks. Compared with longer‑acting agents such as diazepam, alprazolam may require more careful tapering to avoid withdrawal but offers quicker symptom relief.

Neurol Sr should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the tablets away from moisture, direct sunlight and heat sources to maintain potency throughout its shelf life.

Neurol Sr is supplied as oral tablets. Patients should swallow the tablet whole with a glass of water, unless otherwise directed by a healthcare professional. It is taken by mouth as prescribed, typically with or without food.

The most serious risks include the potential for physical dependence, severe withdrawal symptoms upon abrupt discontinuation, respiratory depression especially when combined with other depressants, and rare allergic reactions such as rash or angioedema. Close medical supervision is essential.

Neurol Sr should be avoided in patients with severe respiratory insufficiency, acute narrow‑angle glaucoma, known hypersensitivity to alprazolam or other benzodiazepines, and in individuals who are currently abusing alcohol or other CNS depressants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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