Product image of Neuromultivit (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride) supplied by GNH India

Neuromultivit

Active Ingredient:
Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride
Origin:
EU

Neuromultivit (Thiamine Hydrochloride, Cyanocobalamin, Pyridoxine Hydrochloride)

Thiamine Hydrochloride, the active ingredient in Neuromultivit, is a Vitamin B complex supplement presented as an intramuscular formulation for injection use. It addresses deficiencies of vitamins B1, B6, and B12 in patients who require parenteral nutrition or have documented vitamin B deficiencies.

GNH India supplies Neuromultivit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

G.L. Pharma Gmbh

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Indications & Clinical Uses

Neuromultivit, a vitamin B complex supplement, supports metabolic pathways that depend on B‑vitamin cofactors.

  • Vitamin B1 deficiency: restores thiamine levels to improve carbohydrate metabolism.
  • Vitamin B6 deficiency: replenishes pyridoxine to aid amino‑acid processing and neurotransmitter synthesis.
  • Vitamin B12 deficiency: supplies cyanocobalamin to support fatty‑acid metabolism and red blood cell formation.

How It Works

  • Thiamine Hydrochloride, Pyridoxine Hydrochloride, and Cyanocobalamin act as essential enzymatic cofactors. Thiamine (B1) participates in decarboxylation reactions of carbohydrate metabolism, pyridoxine (B6) is required for transamination and neurotransmitter synthesis, and cyanocobalamin (B12) facilitates methylmalonyl‑CoA mutase and homocysteine remethylation. Together they enable proper carbohydrate, amino‑acid, and fatty‑acid metabolic pathways when administered intramuscularly.

Side Effects

Neuromultivit may be associated with a range of adverse reactions following intramuscular administration.

Common Side Effects

  • Injection site pain: mild discomfort at the site of injection.
  • Redness or swelling: transient local erythema.
  • Headache: occasional mild headache.
  • Nausea: occasional feeling of nausea.
  • Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare skin eruption with mucosal involvement.
  • Hemolytic anemia: destruction of red blood cells.
  • Severe thrombocytopenia: markedly low platelet count.

Precautions & Warnings

When using Neuromultivit, consider the following precautions to ensure safe administration.

  • Assess deficiency status: confirm laboratory evidence of B‑vitamin deficiency before initiating therapy.
  • Monitor for allergic reactions: observe patients for signs of hypersensitivity after injection.
  • Adjust dose in renal impairment: consider reduced dosing in patients with severe renal dysfunction.
  • Avoid concurrent high‑dose B‑vitamin supplements: risk of cumulative toxicity.
  • Pregnancy and lactation: use only if clearly indicated and benefits outweigh potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Neuromultivit can interact with certain medications; awareness of these interactions helps prevent reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Methotrexate: may diminish the therapeutic effect of vitamin B12.
  • Phenytoin: can increase metabolism of pyridoxine, lowering its plasma levels.
  • Tetracyclines: may chelate thiamine, reducing its absorption.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may alter pyridoxine metabolism, requiring monitoring.
  • Metformin: associated with reduced vitamin B12 absorption over long‑term use.
  • Alcohol consumption: increases thiamine requirement and may exacerbate deficiency.

Frequently Asked Questions

Neuromultivit is a vitamin B complex injectable that provides thiamine (B1), pyridoxine (B6) and cyanocobalamin (B12). It is used to correct documented deficiencies of these B‑vitamins in patients who cannot take oral supplements or who require rapid repletion, such as those receiving parenteral nutrition or with malabsorption disorders.

Thiamine hydrochloride supplies thiamine, a cofactor for enzymes involved in carbohydrate decarboxylation, such as pyruvate dehydrogenase. By restoring thiamine levels, it enables normal glucose metabolism, energy production, and nerve function. In Neuromultivit, thiamine works together with pyridoxine and cyanocobalamin to support broader metabolic pathways.

The specific dose of Neuromultivit is determined by the prescribing clinician based on the patient’s deficiency severity, body weight, renal function and clinical context. Healthcare professionals calculate the appropriate amount of each vitamin B component and the injection frequency, and the regimen is documented in the patient’s medical record.

Safety data for Neuromultivit in pregnancy and lactation are limited. It should be administered only when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under the guidance of a qualified obstetrician. Breastfeeding mothers should consult their healthcare provider before use.

To place an order, visit the product page on gnhindia.com, enter the required quantity and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Neuromultivit combines three B‑vitamins (B1, B6, B12) in a single intramuscular formulation, whereas many alternatives contain only one vitamin per vial. This multi‑vitamin approach can reduce the number of injections needed for patients with multiple deficiencies, but clinicians may prefer single‑vitamin products when only one deficiency is present or when dosing flexibility is required.

Neuromultivit should be stored at 2‑8 °C in a refrigerator. Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking the product. If temporary temperature excursions occur, discard any vial that shows signs of discoloration or particulate matter.

Neuromultivit is given by intramuscular injection, typically into the deltoid or gluteal muscle. The injection should be performed by a qualified healthcare professional using aseptic technique. The volume and injection site are selected according to the prescribed dose and patient’s muscle mass.

The most serious adverse reactions include anaphylaxis, severe hypersensitivity, Stevens‑Johnson syndrome, hemolytic anemia and severe thrombocytopenia. Patients should be monitored closely after the first injection, and any signs of systemic allergic response or unusual skin or blood abnormalities require immediate medical evaluation.

Neuromultivit is contraindicated in individuals with known hypersensitivity to any of its ingredients, including thiamine, pyridoxine or cyanocobalamin. Patients with a history of severe allergic reactions to vitamin B injections, or those receiving conflicting high‑dose vitamin B supplements without medical supervision, should avoid its use unless advised otherwise by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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