Neurontin (Gabapentin)

Gabapentin binds to the α2δ subunit of voltage‑gated calcium channels in the central nervous system, limiting calcium entry into neurons. This reduces the release of excitatory neurotransmitters, thereby decreasing neuronal hyper‑excitability that contributes to seizures and neuropathic pain.

The dose of Neurontin is individualized by the prescribing clinician based on the specific indication, patient age, renal function and response. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for gabapentin in pregnancy are limited, and the product is classified as having an unknown pregnancy category. It is excreted in breast milk, so healthcare providers should weigh potential benefits against risks before use in pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with older anticonvulsants such as carbamazepine, gabapentin has a different mechanism targeting calcium channels rather than sodium channels. It is generally better tolerated for neuropathic pain but may cause more dizziness and somnolence; efficacy and safety profiles should be evaluated for each patient.

Neurontin tablets should be stored at room temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the container tightly closed and out of reach of children.

Neurontin is taken orally, usually with or without food, as prescribed by a healthcare professional. The tablets are swallowed whole with a glass of water; crushing or chewing is not recommended unless specifically instructed.

Serious risks include severe allergic reactions (rash, swelling, breathing difficulty), suicidal thoughts or behavior, and acute respiratory depression, especially when combined with other central nervous system depressants. Patients should seek immediate medical attention if any of these occur.

Neurontin is contraindicated in patients with known hypersensitivity to gabapentin or any excipients in the formulation. Caution is advised for individuals with severe renal impairment, uncontrolled depression, or those taking multiple CNS depressants.